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There are limited data correlating symptoms with reflux episodes during pH studies after peroral endoscopic myotomy.
METHODS:Consecutive patients who underwent POEM followed up ≥6 months later by 48-hour ambulatory wireless pH testing off antisecretory therapy were identified. Reflux symptom association was defined as symptom association probability >95%.
RESULTS:The most frequent symptoms of heartburn (47.2%), cough (45.1%), and chest pain (39.6%) were associated with a positive reflux symptom association (symptom association probability >95%) in 20.9%, 17.1%, and 19.4%, respectively.
DISCUSSION:There is poor correlation between reported symptoms and esophageal acid exposure during pH testing after POEM.
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