Clinical Report: Midday Removal and Reinsertion of Soft Contact Lens Cannot Prevent Post-lens Tear-film Hyperosmolarity

1Herbert Wertheim School of Optometry & Vision Science, University of California, Berkeley, Berkeley, California

2Chemical and Biomolecular Engineering Department, University of California, Berkeley, Berkeley, California

3Clinical Research Center, University of California, Berkeley, Berkeley, California

4CooperVision Inc., Pleasanton, California

[email protected]

Submitted: March 30, 2022

Accepted: July 3, 2022

Funding/Support: CooperVision Inc. (to CJR) and Roberta J. Smith Foundation (to MCL).

Conflict of Interest Disclosure: One of the authors (C-CP) is an employee of CooperVision Inc. and has financial conflicts of interest. CooperVision Inc. partially funded this research. Access, control, and ownership of the data belong to the authors and not CooperVision Inc. CooperVision Inc. did not have any decision in submitting this article for peer review.

The authors (CJR and MCL) received research funding from CooperVision Inc. but are not financially affiliated with CooperVision Inc. CJR served as a consultant for Alcon and Verily in the past, but the work is unrelated to the manuscript topic. MCL received researching funding from Johnson & Johnson Vision and Verily, but the researching funding is unrelated to the manuscript topic. YHK and TN have no financial conflict of interest.

Author Contributions: Conceptualization: YHK, CJR; Data Curation: YHK; Formal Analysis: YHK, TN, C-CP, CJR; Funding Acquisition: CJR; Investigation: YHK, TN, CJR; Methodology: YHK, C-CP, CJR; Project Administration: YHK; Resources: CJR; Software: CJR; Supervision: MCL, C-CP, CJR; Validation: YHK, TN, CJR; Visualization: C-CP, CJR; Writing – Original Draft: YHK; Writing – Review & Editing: YHK, MCL, C-CP, CJR.

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