Igwaran A, Okoh AI. Human campylobacteriosis: a public health concern of global importance. Heliyon. 2019;5(11):1–14. https://doi.org/10.1016/j.heliyon.2019.e02814.

Article  Google Scholar 

Zhang Q, Sahin O. Campylobacteriosis. In: Swayne DE, editor. Diseases of Poultry. 14th ed. Hoboken, United States: John Wiley and Sons Ltd; 2020. p. 754–69. https://doi.org/10.1002/9781119371199.ch17.

Chapter  Google Scholar 

Wallace JS, Stanley KN, Jones K. The colonization of turkeys by thermophilic Campylobacters. J Appl Microbiol. 1998;85(2):224–30. https://doi.org/10.1046/j.1365-2672.1998.00470.x.

CAS  Article  PubMed  Google Scholar 

Awad WA, Hess C, Hess M. Re-thinking the chicken-Campylobacter jejuni interaction: a review. Avian Pathol. 2018;47(4):352–63. https://doi.org/10.1080/03079457.2018.1475724.

Article  PubMed  Google Scholar 

Van Deun K, Pasmans F, Van Immerseel F, Ducatelle R, Haesebrouck F. Butyrate protects Caco-2 cells from Campylobacter jejuni invasion and translocation. Br J Nutr. 2008;100(3):480–4. https://doi.org/10.1017/S0007114508921693.

CAS  Article  PubMed  Google Scholar 

Awad WA, Molnar A, Aschenbach JR, Ghareeb K, Khayal B, Hess C, Liebhart D, Dublecz K, Hess M. Campylobacter infection in chickens modulates the intestinal epithelial barrier function. J Innate Immun. 2015;21(2):151–60. https://doi.org/10.1177/1753425914521648.

CAS  Article  Google Scholar 

Pielsticker C, Glunder G, Aung YH, Rautenschlein S. Colonization pattern of C. jejuni isolates of human and avian origin and differences in the induction of immune responses in chicken. Vet Immunol Immunopathol. 2016;169:1–9. https://doi.org/10.1016/j.vetimm.2015.11.005.

CAS  Article  PubMed  Google Scholar 

Awad WA, Aschenbach JR, Ghareeb K, Khayal B, Hess C, Hess M. Campylobacter jejuni influences the expression of nutrient transporter genes in the intestine of chickens. Vet Microbiol. 2014;172(1–2):195–201. https://doi.org/10.1016/j.vetmic.2014.04.001.

CAS  Article  PubMed  Google Scholar 

Awad WA, Mann E, Dzieciol M, Hess C, Schmitz-Esser S, Wagner M, Hess M. Age-related differences in the luminal and mucosa-associated gut microbiome of broiler chickens and shifts associated with Campylobacter jejuni infection. Front Cell Infect Microbiol. 2016;6:1–17. https://doi.org/10.3389/fcimb.2016.00154.

Article  Google Scholar 

Awad WA, Dublecz F, Hess C, Dublecz K, Khayal B, Aschenbach JR, Hess M. Campylobacter jejuni colonization promotes the translocation of Escherichia coli to extra-intestinal organs and disturbs the short-chain fatty acids profiles in the chicken gut. Poult Sci. 2016;95(10):2259–65. https://doi.org/10.3382/ps/pew151.

CAS  Article  PubMed  Google Scholar 

Backert S, Boehm M, Wessler S, Tegtmeyer N. Transmigration route of Campylobacter jejuni across polarized intestinal epithelial cells: paracellular, transcellular or both? Cell Commun Signal. 2013;11:1–15. https://doi.org/10.1186/1478-811x-11-72.

Article  Google Scholar 

Humphrey S, Chaloner G, Kemmett K, Davidson N, Williams N, Kipar A, Humphrey T, Wigley P. Campylobacter jejuni is not merely a commensal in commercial broiler chickens and affects bird welfare. mBio. 2014;5(4):1–7. https://doi.org/10.1128/mBio.01364-14.

CAS  Article  Google Scholar 

Sylte MJ, Sivasankaran SK, Trachsel J, Sato Y, Wu Z, Johnson TA, Chandra LC, Zhang Q, Looft T. The acute host-response of turkeys colonized with Campylobacter coli. Front Vet Sci. 2021;8:1–11. https://doi.org/10.3389/fvets.2021.613203.

Article  Google Scholar 

de Zoete MR, Keestra AM, Roszczenko P, van Putten JPM. Activation of human and chicken toll-like receptors by Campylobacter spp. Infect Immun. 2010;78(3):1229–38. https://doi.org/10.1128/Iai.00897-09.

Article  PubMed  Google Scholar 

Sylte MJ, Johnson TA, Meyer EL, Inbody MH, Trachsel J, Looft T, Susta L, Wu Z, Zhang Q. Intestinal colonization and acute immune response in commercial turkeys following inoculation with Campylobacter jejuni constructs encoding antibiotic-resistance markers. Vet Immunol Immunopathol. 2019;210:6–14. https://doi.org/10.1016/j.vetimm.2019.02.003.

CAS  Article  PubMed  Google Scholar 

Scupham AJ. Succession in the intestinal microbiota of preadolescent turkeys. FEMS Microbiol Ecol. 2007;60(1):136–47. https://doi.org/10.1111/j.1574-6941.2006.00245.x.

CAS  Article  PubMed  Google Scholar 

Wilkinson TJ, Cowan AA, Vallin HE, Onime LA, Oyama LB, Cameron SJ, Gonot C, Moorby JM, Waddams K, Theobald VJ, Leemans D, Bowra S, Nixey C, Huws SA. Characterization of the microbiome along the gastrointestinal tract of growing turkeys. Front Microbiol. 2017;8:1–11. https://doi.org/10.3389/fmicb.2017.01089.

Article  Google Scholar 

Kubasova T, Kollarcikova M, Crhanova M, Karasova D, Cejkova D, Sebkova A, Matiasovicova J, Faldynova M, Pokorna A, Cizek A, Rychlik I. Contact with adult hen affects development of caecal microbiota in newly hatched chicks. PLoS One. 2019;14(3):1–13. https://doi.org/10.1371/journal.pone.0212446.

CAS  Article  Google Scholar 

Connerton PL, Richards PJ, Lafontaine GM, O’Kane PM, Ghaffar N, Cummings NJ, Smith DL, Fish NM, Connerton IF. The effect of the timing of exposure to Campylobacter jejuni on the gut microbiome and inflammatory responses of broiler chickens. Microbiome. 2018;6(88):1–17. https://doi.org/10.1186/s40168-018-0477-5.

Article  Google Scholar 

Dhillon AS, Shivaprasad HL, Schaberg D, Wier F, Weber S, Bandli D. Campylobacter jejuni infection in broiler chickens. Avian Dis. 2006;50(1):55–8. https://doi.org/10.1637/7411-071405r.1.

Article  PubMed  Google Scholar 

Alter T, Weber RM, Hamedy A, Glunder G. Carry-over of thermophilic Campylobacter spp. between sequential and adjacent poultry flocks. Vet Microbiol. 2011;147(1–2):90–5. https://doi.org/10.1016/j.vetmic.2010.06.005.

Article  PubMed  Google Scholar 

Aviagen Turkeys. B.U.T. 6 Performance Objectives. vol POBRB6/EN. 5th ed. Tattenhall, United Kingdom: Aviagen Turkeys Limited; 2020.

Google Scholar 

Beery JT, Hugdahl MB, Doyle MP. Colonization of gastrointestinal tracts of chicks by Campylobacter jejuni. Appl Environ Microbiol. 1988;54(10):2365–70. https://doi.org/10.1128/aem.54.10.2365-2370.1988.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Wassenaar TM, Vanderzeijst BAM, Ayling R, Newell DG. Colonization of chicks by motility mutants of Campylobacter jejuni demonstrates the importance of flagellin-a expression. J Gen Microbiol. 1993;139:1171–5. https://doi.org/10.1099/00221287-139-6-1171.

CAS  Article  PubMed  Google Scholar 

Chaloner G, Wigley P, Humphrey S, Kemmett K, Lacharme-Lora L, Humphrey T, Williams N. Dynamics of dual infection with Campylobacter jejuni strains in chickens reveals distinct strain-to-strain variation in infection ecology. Appl Environ Microbiol. 2014;80(20):6366–72. https://doi.org/10.1128/Aem.01901-14.

Article  PubMed  PubMed Central  Google Scholar 

Cox NA, Hofacre CL, Bailey JS, Buhr RJ, Wilson JL, Hiett KL, Richardson LJ, Musgrove MT, Cosby DE, Tankson JD, Vizzier YL, Cray PF, Vaughn LE, Holt PS, Bourassa DV. Presence of Campylobacter jejuni in various organs one hour, one day, and one week following oral or intracloacal inoculations of broiler chicks. Avian Dis. 2005;49(1):155–8. https://doi.org/10.1637/7234-070704r.

CAS  Article  PubMed  Google Scholar 

Backert S, Hofreuter D. Molecular methods to investigate adhesion, transmigration, invasion and intracellular survival of the foodborne pathogen Campylobacter jejuni. J Microbiol Methods. 2013;95(1):8–23. https://doi.org/10.1016/j.mimet.2013.06.031.

CAS  Article  PubMed  Google Scholar 

Kwon O, Han TS, Son MY. Intestinal morphogenesis in development, regeneration, and disease: the potential utility of intestinal organoids for studying compartmentalization of the crypt-villus structure. Front Cell Dev Biol. 2020;8:1–14. https://doi.org/10.3389/fcell.2020.593969.

Article  Google Scholar 

Powell FL, Rothwell L, Clarkson MJ, Kaiser P. The turkey, compared to the chicken, fails to mount an effective early immune response to Histomonas meleagridis in the gut. Parasite Immunol. 2009;31(6):312–27. https://doi.org/10.1111/j.1365-3024.2009.01113.x.

CAS  Article  PubMed  Google Scholar 

Garriga C, Rovira N, Moreto M, Planas JM. Expression of Na+-D-glucose cotransporter in brush-border membrane of the chicken intestine. Am J Physiol Regul Integr Comp Physiol. 1999;276(2):627–31. https://doi.org/10.1152/ajpregu.1999.276.2.R627.

Article  Google Scholar 

Awad WA, Hess C, Khayal B, Aschenbach JR, Hess M. In vitro exposure to Escherichia coli decreases ion conductance in the jejunal epithelium of broiler chickens. PLoS One. 2014;9(3):1–8. https://doi.org/10.1371/journal.pone.0092156.

CAS  Article  Google Scholar 

Riesenfeld G, Sklan D, Bar A, Eisner U, Hurwitz S. Glucose-absorption and starch digestion in the intestine of the chicken. J Nutr. 1980;110(1):117–21. https://doi.org/10.1093/jn/110.1.117.

CAS  Article  PubMed  Google Scholar 

Pinca A, Bautista N, Adiova C, Sangel P. Comparative expression analysis of small intestine nutrient transporters sodium/glucose cotransporter 1 (SGLT1) and peptide transporter 1 (PepT1) between Itik Pinas (Anas platyrhynchos L.) and commercial layer chicken (Gallus gallus domesticus). Philipp J Sci. 2019;148:433–9.

Google Scholar 

Li H, Cheng J, Yuan Y, Luo R, Zhu Z. Age-related intestinal monosaccharides transporters expression and villus surface area increase in broiler and layer chickens. J Anim Physiol Anim Nutr (Berl). 2020;104(1):144–55. https://doi.org/10.1111/jpn.13211.

CAS  Article  Google Scholar 

Thorens B. GLUT2, glucose sensing and glucose homeostasis. Diabetologia. 2015;58(2):221–32. https://doi.org/10.1007/s00125-014-3451-1.

CAS  Article  PubMed  Google Scholar 

Dharmsathaphorn K, Pandol SJ. Mechanism of chloride secretion induced by carbachol in a colonic epithelial-cell line. J Clin Invest. 1986;77(2):348–54. https://doi.org/10.1172/Jci112311.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Schwarz A, Gauly M, Abel H, Das G, Humburg J, Weiss AT, Breves G, Rautenschlein S. Pathobiology of Heterakis gallinarum mono-infection and co-infection with Histomonas meleagridis in layer chickens. Avian Pathol. 2011;40(3):277–87. https://doi.org/10.1080/03079457.2011.561280.

CAS  Article  PubMed  Google Scholar 

Moran O, Zegarra-Moran O. On the measurement of the functional properties of the CFTR. J Cyst Fibros. 2008;7(6):483–94. https://doi.org/10.1016/j.jcf.2008.05.003.

CAS  Article  PubMed  Google Scholar 

Nighot PK, Blikslager AT. ClC-2 regulates mucosal barrier function associated with structural changes to the vill