A bioinformatics analysis: ZFHX4 is associated with metastasis and poor survival in ovarian cancer

Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer Statistics, 2021. CA: Cancer J Clin. 2021;71(1):7–33.

Google Scholar 

Wang Z, Guo E, Yang B, Xiao R, Lu F, You L, Chen G. Trends and age-period-cohort effects on mortality of the three major gynecologic cancers in China from 1990 to 2019: Cervical, ovarian and uterine cancer. Gynecol Oncol. 2021;163(2):358–63.

PubMed  Article  Google Scholar 

Roberts CM, Cardenas C, Tedja R. The role of intra-tumoral heterogeneity and its clinical relevance in epithelial ovarian cancer recurrence and metastasis. Cancers (Basel). 2019;11(8):1083.

CAS  Article  Google Scholar 

Bregenzer ME, Horst EN, Mehta P, Novak CM, Repetto T, Mehta G. The role of cancer stem cells and mechanical forces in ovarian cancer metastasis. Cancers (Basel). 2019;11(7):1008.

CAS  Article  Google Scholar 

Rodriguez GC, Haisley C, Hurteau J, Moser TL, Whitaker R, Bast RC Jr, Stack MS. Regulation of invasion of epithelial ovarian cancer by transforming growth factor-beta. Gynecol Oncol. 2001;80(2):245–53.

CAS  PubMed  Article  Google Scholar 

Dhaliwal D, Shepherd TG. Molecular and cellular mechanisms controlling integrin-mediated cell adhesion and tumor progression in ovarian cancer metastasis: a review. Clin Exp Metastasis. 2022;39(2):291–301.

CAS  PubMed  Article  Google Scholar 

Yousefi M, Dehghani S, Nosrati R, Ghanei M, Salmaninejad A, Rajaie S, Hasanzadeh M, Pasdar A. Current insights into the metastasis of epithelial ovarian cancer - hopes and hurdles. Cell Oncol (Dordr). 2020;43(4):515–38.

Article  Google Scholar 

Bachman KE, Park BH. Duel nature of TGF-beta signaling: tumor suppressor vs. tumor promoter. Curr Opin Oncol. 2005;17(1):49–54.

CAS  PubMed  Article  Google Scholar 

Winer A, Adams S, Mignatti P. Matrix metalloproteinase inhibitors in cancer therapy: turning past failures into future successes. Mol Cancer Ther. 2018;17(6):1147–55.

CAS  PubMed  PubMed Central  Article  Google Scholar 

van de Vijver MJ, He YD, van’t Veer LJ, Dai H, Hart AA, Voskuil DW, Schreiber GJ, Peterse JL, Roberts C, Marton MJ, et al. A gene-expression signature as a predictor of survival in breast cancer. New England J Med. 2002;347(25):1999–2009.

Article  Google Scholar 

Sundar R, Barr Kumarakulasinghe N, Huak Chan Y, Yoshida K, Yoshikawa T, Miyagi Y, Rino Y, Masuda M, Guan J, Sakamoto J, et al. Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial. Gut. 2022;71(4):676–85.

CAS  PubMed  Article  Google Scholar 

Liu SY, Bao H, Wang Q, Mao WM, Chen Y, Tong X, Xu ST, Wu L, Wei YC, Liu YY, et al. Genomic signatures define three subtypes of EGFR-mutant stage II-III non-small-cell lung cancer with distinct adjuvant therapy outcomes. Nat Commun. 2021;12(1):6450.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Chen C, Chen H, Zhang Y, Thomas HR, Frank MH, He Y, Xia R. TBtools: an integrative toolkit developed for interactive analyses of big biological data. Mol Plant. 2020;13(8):1194–202.

CAS  PubMed  Article  Google Scholar 

Zhou Y, Zhou B, Pache L, Chang M, Khodabakhshi AH, Tanaseichuk O, Benner C, Chanda SK. Metascape provides a biologist-oriented resource for the analysis of systems-level datasets. Nat Commun. 2019;10(1):1523.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Hanzelmann S, Castelo R, Guinney J. GSVA: gene set variation analysis for microarray and RNA-seq data. BMC Bioinformatics. 2013;14:7.

PubMed  PubMed Central  Article  Google Scholar 

Sestito R, Tocci P, Roman C, Di Castro V, Bagnato A. Functional interaction between endothelin-1 and ZEB1/YAP signaling regulates cellular plasticity and metastasis in high-grade serous ovarian cancer. J Exp Clin Cancer Res. 2022;41(1):157.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Shi X, Yu X, Wang J, Bian S, Li Q, Fu F, Zou X, Zhang L, Bast RC, Jr., Lu Z et al. SIK2 promotes ovarian cancer cell motility and metastasis by phosphorylating MYLK. Mol Oncol. 2022;16(13):2558-74.

Mitra S, Tiwari K, Podicheti R, Pandhiri T, Rusch DB, Bonetto A, Zhang C, Mitra AK. Transcriptome profiling reveals matrisome alteration as a key feature of ovarian cancer progression. Cancers (Basel). 2019;11(10):1513.

CAS  Article  Google Scholar 

Winkler J, Abisoye-Ogunniyan A, Metcalf KJ, Werb Z. Concepts of extracellular matrix remodelling in tumour progression and metastasis. Nat Commun. 2020;11(1):5120.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Popova NV, Jucker M. The functional role of extracellular matrix proteins in cancer. Cancers (Basel). 2022;14(1):238.

CAS  Article  Google Scholar 

Grossen A, Smith K, Coulibaly N, Arbuckle B, Evans A, Wilhelm S, Jones K, Dunn I, Towner R, Wu D, et al. Physical forces in glioblastoma migration: a systematic review. Int J Mol Sci. 2022;23(7):4055.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Biffi G, Tuveson DA. Diversity and biology of cancer-associated fibroblasts. Physiol Rev. 2021;101(1):147–76.

CAS  PubMed  Article  Google Scholar 

Glentis A, Oertle P, Mariani P, Chikina A, El Marjou F, Attieh Y, Zaccarini F, Lae M, Loew D, Dingli F, et al. Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane. Nat Commun. 2017;8(1):924.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Setargew YFI, Wyllie K, Grant RD, Chitty JL, Cox TR. Targeting lysyl oxidase family meditated matrix cross-linking as an anti-stromal therapy in solid tumours. Cancers (Basel). 2021;13(3):491.

CAS  Article  Google Scholar 

Fang M, Yuan J, Peng C, Li Y. Collagen as a double-edged sword in tumor progression. Tumour Biol. 2014;35(4):2871–82.

CAS  PubMed  Article  Google Scholar 

Romer AMA, Thorseth ML, Madsen DH. Immune modulatory properties of collagen in cancer. Front Immunol. 2021;12:791453.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Yue H, Li W, Chen R, Wang J, Lu X, Li J. Stromal POSTN induced by TGF-beta1 facilitates the migration and invasion of ovarian cancer. Gynecol Oncol. 2021;160(2):530–8.

CAS  PubMed  Article  Google Scholar 

Steitz AM, Steffes A, Finkernagel F, Unger A, Sommerfeld L, Jansen JM, Wagner U, Graumann J, Muller R, Reinartz S. Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C. Cell Death Dis. 2020;11(4):249.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Lecker LSM, Berlato C, Maniati E, Delaine-Smith R, Pearce OMT, Heath O, Nichols SJ, Trevisan C, Novak M, McDermott J, et al. TGFBI production by macrophages contributes to an immunosuppressive microenvironment in ovarian cancer. Cancer Res. 2021;81(22):5706–19.

CAS  PubMed  Article  Google Scholar 

Parthasarathi KTS, Mandal S, Singh S, Gundimeda S, Jolly MK, Pandey A, Sharma J. In silico analysis of ion channels and their correlation with epithelial to mesenchymal transition in breast cancer. Cancers (Basel). 2022;14(6):1444.

CAS  Article  Google Scholar 

Prevarskaya N, Skryma R, Shuba Y. Ion Channels in cancer: are cancer hallmarks oncochannelopathies? Physiol Rev. 2018;98(2):559–621.

CAS  PubMed  Article  Google Scholar 

Liang X, Zhang N, Pan H, Xie J, Han W. Development of store-operated calcium entry-targeted compounds in cancer. Front Pharmacol. 2021;12:688244.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Sun J, Lu F, He H, Shen J, Messina J, Mathew R, Wang D, Sarnaik AA, Chang WC, Kim M, et al. STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion. J Cell Biol. 2014;207(4):535–48.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Tiffner A, Hopl V, Schober R, Sallinger M, Grabmayr H, Hoglinger C, Fahrner M, Lunz V, Maltan L, Frischauf I, et al. Orai1 Boosts SK3 Channel Activation. Cancers (Basel). 2021;13(24):6357.

CAS  Article  Google Scholar 

Gueguinou M, Crottes D, Chantome A, Rapetti-Mauss R, Potier-Cartereau M, Clarysse L, Girault A, Fourbon Y, Jezequel P, Guerin-Charbonnel C, et al. The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca(2+) homeostasis. Oncogene. 2017;36(25):3640–7.

CAS  PubMed  Article  Google Scholar 

James AD, Leslie TK, Kaggie JD, Wiggins L, Patten L, Murphy O'Duinn J, Langer S, Labarthe MC, Riemer F, Baxter G, et al. Sodium accumulation in breast cancer predicts malignancy and treatment response. Br J Cancer. 2022;127(2):337-49.

Brisson L, Gillet L, Calaghan S, Besson P, Le Guennec JY, Roger S, Gore J. Na(V)15 enhances breast cancer cell invasiveness by increasing NHE1-dependent H(+) efflux in caveolae. Oncogene. 2011;30(17):2070–6.

CAS  PubMed  Article  Google Scholar 

Hemmi K, Ma D, Miura Y, Kawaguchi M, Sasahara M, Hashimoto-Tamaoki T, Tamaoki T, Sakata N, Tsuchiya K. A homeodomain-zinc finger protein, ZFHX4, is expressed in neuronal differentiation manner and suppressed in muscle differentiation manner. Biol Pharm Bull. 2006;29(9):1830–5.

CAS  PubMed  Article  Google Scholar 

Fevre-Montange M, Champier J, Szathmari A, Wierinckx A, Mottolese C, Guyotat J, Figarella-Branger D, Jouvet A, Lachuer J. Microarray analysis reveals differential gene expression patterns in tumors of the pineal region. J Neuropathol Exp Neurol. 2006;65(7):675–84.

CAS  PubMed 

留言 (0)

沒有登入
gif