Dietary Guidelines Advisory Committee. 2020. Scientific Report of the 2020 Dietary Guidelines Advisory Committee: Advisory Report to the Secretary of Agriculture and the Secretary of Health and Human Services. U.S. Department of Agriculture, Agricultural Research Service, Washington, DC.

Schulze MB, Martínez-González MA, Fung TT, Lichtenstein AH, Forouhi NG. Food based dietary patterns and chronic disease prevention. BMJ 2018;361:k2396.

PubMed  PubMed Central  Article  Google Scholar 

Bruins MJ, Van Dael P, Eggersdorfer M. The role of nutrients in reducing the risk for noncommunicable diseases during aging. Nutrients 2019;11:85.

CAS  PubMed Central  Article  Google Scholar 

Wang DD, Li Y, Afshin A, Springmann M, Mozaffarian D, Stampfer MJ, et al. Global improvement in dietary quality could lead to substantial reduction in premature death. J Nutr. 2019;149:1065–74.

PubMed  PubMed Central  Article  Google Scholar 

Ley SH, Pan A, Li Y, Manson JE, Willett WC, Sun Q, et al. Changes in overall diet quality and subsequent type 2 diabetes risk: Three U.S. prospective cohorts. Diabetes Care. 2016;39:2011–8.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Xu Z, Steffen LM, Selvin E, Rebholz CM. Diet quality, change in diet quality and risk of incident CVD and diabetes. Public Health Nutr. 2020;23:329–38.

PubMed  Article  Google Scholar 

Fung TT, Pan A, Hou T, Chiuve SE, Tobias DK, Mozaffarian D, et al. Long-term change in diet quality is associated with body weight change in men and women. J Nutr. 2015;145:1850–6.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Kang M, Boushey CJ, Shvetsov YB, Setiawan VW, Paik HY, Wilkens LR, et al. Changes in diet quality and body weight over 10 years: The Multiethnic Cohort Study. Br J Nutr. 2021;126:1389–97.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Sotos-Prieto M, Bhupathiraju SN, Mattei J, Fung TT, Li Y, Pan A, et al. Changes in diet quality scores and risk of cardiovascular disease among us men and women. Circulation 2015;132:2212–9.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Sotos-Prieto M, Bhupathiraju SN, Mattei J, Fung TT, Li Y, Pan A, et al. Association of changes in diet quality with total and cause-specific mortality. N. Engl J Med. 2017;377:143–53.

PubMed  PubMed Central  Article  Google Scholar 

Sofi F, Macchi C, Abbate R, Gensini GF, Casini A. Mediterranean diet and health status: an updated meta-analysis and a proposal for a literature-based adherence score. Public Health Nutr. 2014;17:2769–82.

PubMed  Article  Google Scholar 

Dinu M, Pagliai G, Casini A, Sofi F. Mediterranean diet and multiple health outcomes: an umbrella review of meta-analyses of observational studies and randomised trials. Eur J Clin Nutr. 2018;72:30–43.

CAS  PubMed  Article  Google Scholar 

Grosso G, Mistretta A, Frigiola A, Gruttadauria S, Biondi A, Basile F, et al. Mediterranean diet and cardiovascular risk factors: a systematic review. Crit Rev Food Sci Nutr. 2014;54:593–610.

CAS  PubMed  Article  Google Scholar 

Bonaccio M, Cerletti C, Iacoviello L, de Gaetano G. Mediterranean diet and low-grade subclinical inflammation: the Moli-sani study. Endocr Metab Immune Disord Drug Targets. 2015;15:18–24.

CAS  PubMed  Article  Google Scholar 

Kromhout D, Keys A, Aravanis C, Buzina R, Fidanza F, Giampaoli S, et al. Food consumption patterns in the 1960s in seven countries. Am J Clin Nutr. 1989;49:889–94.

CAS  PubMed  Article  Google Scholar 

Wang DD, Li Y, Chiuve SE, Stampfer MJ, Manson JE, Rimm EB, et al. Association of specific dietary fats with total and cause-specific mortality. JAMA Intern Med. 2016;176:1134–45.

PubMed  PubMed Central  Article  Google Scholar 

O’Sullivan TA, Hafekost K, Mitrou F, Lawrence D. Food sources of saturated fat and the association with mortality: A meta-analysis. Am J Public Health. 2013;103:e31–4.

PubMed  PubMed Central  Article  Google Scholar 

Reynolds AN, Diep Pham HT, Montez J, Mann J. Dietary fibre intake in childhood or adolescence and subsequent health outcomes: A systematic review of prospective observational studies. Diabetes Obes Metab. 2020;22:2460–7.

CAS  PubMed  PubMed Central  Article  Google Scholar 

McRae MP. Dietary fiber is beneficial for the prevention of cardiovascular disease: An umbrella review of meta-analyses. J Chiropr Med. 2017;16:289–99.

PubMed  PubMed Central  Article  Google Scholar 

Manach C, Scalbert A, Morand C, Remesy C, Jimenez L. Polyphenols: Food sources and bioavailability. Am J Clin Nutr. 2004;79:727–47.

CAS  PubMed  Article  Google Scholar 

van Dam RM, Naidoo N, Landberg R. Dietary flavonoids and the development of type 2 - diabetes and cardiovascular diseases: review of recent findings. Curr Opin Lipido. 2013;24:25–33.

Article  CAS  Google Scholar 

Del Rio D, Rodriguez-Mateos A, Spencer JP, Tognolini M, Borges G, Crozier A. Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxid Redox Signal. 2013;18:1818–92.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Grosso G, Godos J, Lamuela-Raventos R, Ray S, Micek A, Pajak A, et al. A comprehensive meta-analysis on dietary flavonoid and lignan intake and cancer risk: level of evidence and limitations. Mol Nutr Food Res. 2017;61:1600930.

Article  CAS  Google Scholar 

Mendonça RD, Carvalho NC, Martin-Moreno JM, Pimenta AM, Lopes ACS, Gea A, et al. Total polyphenol intake, polyphenol subtypes and incidence of cardiovascular disease: The SUN cohort study. Nutr Metab Cardiovasc Dis. 2019;29:69–78.

PubMed  Article  CAS  Google Scholar 

Castro-Barquero S, Tresserra-Rimbau A, Vitelli-Storelli F, Doménech M, Salas-Salvadó J, Martín-Sánchez V, et al. Dietary polyphenol intake is associated with HDL-cholesterol and a better profile of other components of the metabolic syndrome: A PREDIMED-Plus Sub-Study. Nutrients 2020;12:689.

CAS  PubMed Central  Article  Google Scholar 

Tresserra-Rimbau A, Rimm EB, Medina-Remón A, Martínez-González MA, de la Torre R, Corella D, et al. Inverse association between habitual polyphenol intake and incidence of cardiovascular events in the PREDIMED study. Nutr Metab Cardiovasc Dis. 2014;24:639–47.

CAS  PubMed  Article  Google Scholar 

Steffen Y, Gruber C, Schewe T, Sies H. Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. Arch Biochem Biophys. 2008;469:209e19.

Article  CAS  Google Scholar 

Di Castelnuovo A, Costanzo S, Persichillo M, Olivieri M, de Curtis A, Zito F, et al. Distribution of short and lifetime risks for cardiovascular disease in Italians. Eur j Prev Cardiol. 2012;19:723–30.

PubMed  Article  Google Scholar 

Pisani P, Faggiano F, Krogh V, Palli D, Vineis P, Berrino F. Relative validity and reproducibility of a food frequency dietary questionnaire for use in the Italian EPIC centres. Int J Epidemiol. 1997;26:S152–60.

PubMed  Article  Google Scholar 

Pala V, Sieri S, Palli D, Salvini S, Berrino F, Bellegotti M, et al. Diet in the Italian EPIC cohorts: presentation of data and methodological issues. Tumori. 2003;89:594–607.

PubMed  Article  Google Scholar 

Salvini S, Parpinel M, Gnagnarella P, Maissoneuve P, Turrini A. Banca dati composizione degli alimenti per studi epidemiologici in Italia. Milano: Eur Inst Oncol. 1998. Available online: http://www.bda-ieo.it/wordpress/en/(accessed June 2022).

Trichopoulou A, Costacou T, Bamia C, Trichopoulos D. Adherence to a Mediterranean diet and survival in a Greek population. N. Engl J Med. 2003;348:2599–608.

PubMed  Article  Google Scholar 

Neveu V, Perez-Jiménez J, Vos F, Crespy V, du Chaffaut L, Mennen L, et al. Phenol-Explorer: an online comprehensive database on polyphenol contents in foods. Database (Oxf). 2010;2010:bap024.

CAS  Google Scholar 

Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults-The Evidence Report. National Institutes of Health. Obes Res. 1998;6:464.

The Italian Health Examination Survey OEC/HES data. Available online: https://www.cuore.iss.it/indagini/CuoreData (accessed June 2022).

Estruch R, Ros E, Salas-Salvadó J, Covas MI, Corella D, Arós F, et al. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts. N. Engl J Med. 2018;378:e34.

CAS  PubMed  Article  Google Scholar 

de Lorgeril M, Renaud S, Mamelle N, Salen P, Martin JL, Monjaud I, et al. Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet 1994;343:1454–9.

PubMed  Article  Google Scholar 

Tosti V, Bertozzi B, Fontana L. Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms. J Gerontol A Biol Sci Med Sci. 2018;73 318–26.

CAS  PubMed  Article  Google Scholar 

Crowe FL, Key TJ, Appleby PN, Travis RC, Overvad K, Jakobsen MU, et al. Dietary fat intake and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition. Am J Clin Nutr. 2008;87:1405–13.

CAS  PubMed  Article  Google Scholar 

Guasch-Ferré M, Babio N, Martínez-González MA, Corella D, Ros E, Martín-Peláez S, et al. Dietary fat intake and risk of cardiovascular disease and all-cause mortality in a population at high risk of cardiovascular disease. Am J Clin Nutr. 2015;102:1563–73.

PubMed  Article  CAS  Google Scholar 

Guasch-Ferré M, Li Y, Willett WC, Sun Q, Sampson L, Salas-Salvadó J, et al. Consumption of Olive Oil and Risk of Total and Cause-Specific Mortality Among U.S. Adults. J Am Coll Cardiol. 2022;79:101–12.

PubMed  Article  CAS  Google Scholar 

Schwingshackl L, Hoffmann G. Monounsaturated fatty acids, olive oil and health status: a systematic review and