World Cancer Research Fund/American Institute for Cancer Research (2018). Body fatness and weight gain and the risk of cancer. Continuous Update Project Expert Report. Available at dietandcancerreport.org.

Lauby-Secretan, B., Scoccianti, C., Loomis, D., Grosse, Y., Bianchini, F., & Straif, K. (2016). Body fatness and cancer–Viewpoint of the IARC Working Group. New England Journal of Medicine, 375(8), 794–798. https://doi.org/10.1056/NEJMsr1606602

Article  PubMed  Google Scholar 

Kyrgiou, M., Kalliala, I., Markozannes, G., Gunter, M. J., Paraskevaidis, E., Gabra, H., et al. (2017). Adiposity and cancer at major anatomical sites: Umbrella review of the literature. BMJ, 356, j477. https://doi.org/10.1136/bmj.j477

Article  PubMed  PubMed Central  Google Scholar 

Fang, Z., Song, M., Lee, D., & Giovannucci, E. L. (2021). The role of Mendelian randomization studies in deciphering the effect of obesity on cancer. Journal of the National Cancer Institute. https://doi.org/10.1093/jnci/djab102

Article  PubMed Central  Google Scholar 

Pearson-Stuttard, J., Zhou, B., Kontis, V., Bentham, J., Gunter, M. J., & Ezzati, M. (2018). Worldwide burden of cancer attributable to diabetes and high body-mass index: A comparative risk assessment. The Lancet Diabetes and Endocrinology, 6(6), e6–e15. https://doi.org/10.1016/s2213-8587(18)30150-5

Article  PubMed  Google Scholar 

Hamman, R. F., Wing, R. R., Edelstein, S. L., Lachin, J. M., Bray, G. A., Delahanty, L., et al. (2006). Effect of weight loss with lifestyle intervention on risk of diabetes. Diabetes Care, 29(9), 2102–2107. https://doi.org/10.2337/dc06-0560

Article  PubMed  Google Scholar 

Lahouel, K., Younes, L., Danilova, L., Giardiello, F. M., Hruban, R. H., Groopman, J., et al. (2020). Revisiting the tumorigenesis timeline with a data-driven generative model. Proceedings of the National Academy of Sciences U S A, 117(2), 857–864. https://doi.org/10.1073/pnas.1914589117

CAS  Article  Google Scholar 

Giovannucci, E. (2022). Molecular biologic and epidemiologic insights for preventability of colorectal cancer. Journal of the National Cancer Institute. https://doi.org/10.1093/jnci/djab229

Article  PubMed  Google Scholar 

Ashrafian, H., Ahmed, K., Rowland, S. P., Patel, V. M., Gooderham, N. J., Holmes, E., et al. (2011). Metabolic surgery and cancer. Cancer, 117(9), 1788–1799. https://doi.org/10.1002/cncr.25738

Article  PubMed  Google Scholar 

Nguena Nguefack, H. L., Pagé, M. G., Katz, J., Choinière, M., Vanasse, A., Dorais, M., et al. (2020). Trajectory modelling techniques useful to epidemiological research: A comparative narrative review of approaches. Clinical Epidemiology, 12, 1205–1222. https://doi.org/10.2147/clep.S265287

Article  PubMed  PubMed Central  Google Scholar 

Song, M. (2019). Trajectory analysis in obesity epidemiology: A promising life course approach. Current opinion in endocrine and metabolic research, 4, 37–41.

Article  Google Scholar 

Smith, G. D., & Ebrahim, S. (2003). “Mendelian randomization”: Can genetic epidemiology contribute to understanding environmental determinants of disease? International Journal of Epidemiology, 32(1), 1–22. https://doi.org/10.1093/ije/dyg070

Article  PubMed  Google Scholar 

VanderWeele, T. J., Tchetgen Tchetgen, E. J., Cornelis, M., & Kraft, P. (2014). Methodological challenges in mendelian randomization. Epidemiology, 25(3), 427–435. https://doi.org/10.1097/ede.0000000000000081

Article  PubMed  PubMed Central  Google Scholar 

Richardson, T. G., Sanderson, E., Elsworth, B., Tilling, K., & Davey Smith, G. (2020). Use of genetic variation to separate the effects of early and later life adiposity on disease risk: Mendelian randomisation study. BMJ, 369, m1203. https://doi.org/10.1136/bmj.m1203

Article  PubMed  PubMed Central  Google Scholar 

Sanderson, E., Davey Smith, G., Windmeijer, F., & Bowden, J. (2019). An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings. International Journal of Epidemiology, 48(3), 713–727. https://doi.org/10.1093/ije/dyy262

Article  PubMed  Google Scholar 

Richardson, T. G., Mykkänen, J., Pahkala, K., Ala-Korpela, M., Bell, J. A., Taylor, K., et al. (2021). Evaluating the direct effects of childhood adiposity on adult systemic metabolism: A multivariable Mendelian randomization analysis. International Journal of Epidemiology, 50(5), 1580–1592. https://doi.org/10.1093/ije/dyab051

Article  PubMed  PubMed Central  Google Scholar 

Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J., Stergiakouli, E., Chesi, A., et al. (2016). Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Human Molecular Genetics, 25(2), 389–403. https://doi.org/10.1093/hmg/ddv472

CAS  Article  PubMed  Google Scholar 

Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., et al. (2015). Genetic studies of body mass index yield new insights for obesity biology. Nature, 518(7538), 197–206.

CAS  Article  Google Scholar 

Li, J., Eriksson, M., He, W., Hall, P., & Czene, K. (2017). Associations between childhood body size and seventeen adverse outcomes: Analysis of 65,057 European women. Science and Reports, 7(1), 16917. https://doi.org/10.1038/s41598-017-17258-5

CAS  Article  Google Scholar 

van den Brandt, P. A., Ziegler, R. G., Wang, M., Hou, T., Li, R., Adami, H. O., et al. (2021). Body size and weight change over adulthood and risk of breast cancer by menopausal and hormone receptor status: A pooled analysis of 20 prospective cohort studies. European Journal of Epidemiology, 36(1), 37–55. https://doi.org/10.1007/s10654-020-00688-3

CAS  Article  PubMed  Google Scholar 

Schoemaker, M. J., Nichols, H. B., Wright, L. B., Brook, M. N., Jones, M. E., O’Brien, K. M., et al. (2018). Association of body mass index and age with subsequent breast cancer risk in premenopausal women. JAMA Oncology, 4(11), e181771. https://doi.org/10.1001/jamaoncol.2018.1771

Article  PubMed  PubMed Central  Google Scholar 

Sanchez-Bayona, R., Sayon-Orea, C., Gardeazabal, I., Llorca, J., Gea, A., Santisteban, M., et al. (2021). Body shape trajectories and risk of breast cancer: Results from the SUN ('Seguimiento Universidad De Navarra’) Project. Public Health Nutrition, 24(3), 467–475. https://doi.org/10.1017/s1368980020004322

Article  PubMed  Google Scholar 

Fagherazzi, G., Guillas, G., Boutron-Ruault, M. C., Clavel-Chapelon, F., & Mesrine, S. (2013). Body shape throughout life and the risk for breast cancer at adulthood in the French E3N cohort. European Journal of Cancer Prevention, 22(1), 29–37. https://doi.org/10.1097/CEJ.0b013e328355ec04

Article  PubMed  Google Scholar 

Schoemaker, M. J., Nichols, H. B., Wright, L. B., Brook, M. N., Jones, M. E., O’Brien, K. M., et al. (2020). Adult weight change and premenopausal breast cancer risk: A prospective pooled analysis of data from 628,463 women. International Journal of Cancer, 147(5), 1306–1314. https://doi.org/10.1002/ijc.32892

CAS  Article  PubMed  PubMed Central  Google Scholar 

Tran, T. P. T., Luu, N. M., Bui, T. T., Han, M., Lim, M. K., & Oh, J.-K. (2022). Weight-change trajectory in relation to cancer risk: Findings from a nationwide cohort study in South Korea. Obesity, 30(7), 1507–1519. https://doi.org/10.1002/oby.23464

Article  PubMed  Google Scholar 

Feigelson, H. S., Caan, B., Weinmann, S., Leonard, A. C., Powers, J. D., Yenumula, P. R., et al. (2020). Bariatric surgery is associated with reduced risk of breast cancer in both premenopausal and postmenopausal women. Annals of Surgery, 272(6), 1053–1059. https://doi.org/10.1097/sla.0000000000003331

Article  PubMed  Google Scholar 

Guo, Y., Warren Andersen, S., Shu, X. O., Michailidou, K., Bolla, M. K., Wang, Q., et al. (2016). Genetically predicted body mass index and breast cancer risk: Mendelian randomization analyses of data from 145,000 women of European descent. PLoS Medicine, 13(8), e1002105. https://doi.org/10.1371/journal.pmed.1002105

CAS  Article  PubMed  PubMed Central  Google Scholar 

Chen, Y., Liu, L., Zhou, Q., Imam, M. U., Cai, J., Wang, Y., et al. (2017). Body mass index had different effects on premenopausal and postmenopausal breast cancer risks: A dose-response meta-analysis with 3,318,796 subjects from 31 cohort studies. BMC Public Health, 17(1), 936. https://doi.org/10.1186/s12889-017-4953-9

Article  PubMed  PubMed Central  Google Scholar 

Song, M., Willett, W. C., Hu, F. B., Spiegelman, D., Must, A., Wu, K., et al. (2016). Trajectory of body shape across the lifespan and cancer risk. International Journal of Cancer, 138(10), 2383–2395. https://doi.org/10.1002/ijc.29981

CAS  Article  PubMed  PubMed Central  Google Scholar 

Keum, N., Greenwood, D. C., Lee, D. H., Kim, R., Aune, D., Ju, W., et al. (2015). Adult weight gain and adiposity-related cancers: A dose-response meta-analysis of prospective observational studies. Journal of the National Cancer Institute, 107(2), https://doi.org/10.1093/jnci/djv088.

Teras, L. R., Patel, A. V., Wang, M., Yaun, S. S., Anderson, K., Brathwaite, R., et al. (2020). Sustained weight loss and risk of breast cancer in women 50 years and older: A pooled analysis of prospective data. Journal of the National Cancer Institute, 112(9), 929–937. https://doi.org/10.1093/jnci/djz226

Article  PubMed  Google Scholar 

Eliassen, A. H., Colditz, G. A., Rosner, B., Willett, W. C., & Hankinson, S. E. (2006). Adult weight change and risk of postmenopausal breast cancer. JAMA, 296(2), 193–201. https://doi.org/10.1001/jama.296.2.193

CAS  Article  PubMed  Google Scholar 

Zheng, R., Du, M., Zhang, B., Xin, J., Chu, H., Ni, M., et al. (2018). Body mass index (BMI) trajectories and risk of colorectal cancer in the PLCO cohort. British Journal of Cancer, 119(1), 130–132. https://doi.org/10.1038/s41416-018-0121-y

Article  PubMed  PubMed Central  Google Scholar 

Gao, C., Patel, C. J., Michailidou, K., Peters, U., Gong, J., Schildkraut, J., et al. (2016). Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer. International Journal of Epidemiology, 45(3), 896–908. https://doi.org/10.1093/ije/dyw129

Article  PubMed  PubMed Central  Google Scholar 

Hao, Y., Xiao, J., Liang, Y., Wu, X., Zhang, H., Xiao, C., et al. (2022). Reassessing the causal role of obesity in breast cancer susceptibility: A comprehensive multivariable Mendelian randomization investigating the distribution and timing of exposure. International Journal of Epidemiology. https://doi.org/10.1093/ije/dyac143

Article  PubMed  Google Scholar 

Jensen, B. W., Gamborg, M., Gögenur, I., Renehan, A. G., Sørensen, T. I. A., & Baker, J. L. (2017). Childhood body mass index and height in relation to site-specific risks of colorectal cancers in adult life. European Journal of Epidemiology, 32(12), 1097–1106. https://doi.org/10.1007/s10654-017-0289-0

CAS  Article  PubMed  Google Scholar 

Célind, J., Ohlsson, C., Bygdell, M., Nethander, M., & Kindblom, J. M. (2019). Childhood body mass index is associated with risk of adult colon cancer in men: An association modulated by pubertal change in body mass index. Cancer Epidemiology, Biomarkers & Prevention, 28(5), 974–979. https://doi.org/10.1158/1055-9965.Epi-18-1077

Article  Google Scholar 

Garcia, H., & Song, M. (2019). Early-life obesity and adulthood colorectal cancer risk: A meta-analysis. Revista Panamericana de Salud Pública, 43, e3.