Graves LM, Duncan JS, Whittle MC, Johnson GL. The dynamic nature of the kinome. Biochem J. 2013;450:1–8.

CAS  Article  Google Scholar 

Bayer KU, Schulman H. CaM kinase: still inspiring at 40. Neuron. 2019;103:380–94.

CAS  Article  Google Scholar 

Kawasaki A, Okada M, Tamada A, Okuda S, Nozumi M, Ito Y, Kobayashi D, Yamasaki T, Yokoyama R, Shibata T, Nishina H, Yoshida Y, Fujii Y, Takeuchi K, Igarashi M. Growth cone phosphoproteomics reveals that GAP-43 phosphorylated by JNK is a marker of axon growth and regeneration. iScience. 2018;4:190–203.

CAS  Article  Google Scholar 

Dzamko N, Zhou J, Huang Y, Halliday GM. Parkinson’s disease-implicated kinases in the brain; insights into disease pathogenesis. Front Mol Neurosci. 2014;7:57.

CAS  Article  Google Scholar 

Zhang CX, Engqvist-Goldstein AE, Carreno S, Owen DJ, Smythe E, Drubin DG. Multiple roles for cyclin G-associated kinase in clathrin-mediated sorting events. Traffic. 2005;6:1103–13.

CAS  Article  Google Scholar 

Lee DW, Zhao X, Yim YI, Eisenberg E, Greene LE. Essential role of cyclin-G-associated kinase (Auxilin-2) in developing and mature mice. Mol Biol Cell. 2008;19:2766–76.

CAS  Article  Google Scholar 

Asquith CRM, Berger BT, Wan J, Bennett JM, Capuzzi SJ, Crona DJ, Drewry DH, East MP, Elkins JM, Fedorov O, et al. SGC-GAK-1: a chemical probe for Cyclin G Associated Kinase (GAK). J Med Chem. 2019;62:2830–6.

CAS  Article  Google Scholar 

Cohen P, Cross D, Jänne PA. Kinase drug discovery 20 years after imatinib: progress and future directions. Nat Rev Drug Discov. 2021;20:551–69.

CAS  Article  Google Scholar 

Asquith CRM, Bennett JM, Su L, Laitinen T, Elkins JM, Pickett JE, Wells CI, Li Z, Willson TM, Zuercher WJ. Towards the development of an in vivo chemical probe for Cyclin G associated kinase (GAK). Molecules. 2019;24:4016.

CAS  Article  Google Scholar 

Asquith CRM, Naegeli KM, East MP, Laitinen T, Havener TM, Wells CI, Johnson GL, Drewry DH, Zuercher WJ, Morris DC. Design of a Cyclin G associated kinase (GAK)/epidermal growth factor receptor (EGFR) inhibitor set to interrogate the relationship of EGFR and GAK in Chordoma. J Med Chem. 2019;62:4772–8.

CAS  Article  Google Scholar 

Asquith CRM, Treiber DK, Zuercher WJ. Utilizing comprehensive and mini-kinome panels to optimize the selectivity of quinoline inhibitors for cyclin G associated kinase (GAK). Bioorg Med Chem Lett. 2019;29:1727–31.

CAS  Article  Google Scholar 

Asquith CRM, Laitinen T, Bennett JM, Wells CI, Elkins JM, Zuercher WJ, Tizzard GJ, Poso A. Design and analysis of the 4-anilinoquin(az)oline kinase inhibition profiles of GAK/SLK/STK10 using quantitative structure-activity relationship. ChemMedChem. 2020;15:26–49.

CAS  Article  Google Scholar 

Addeo R, Zappavigna S, Parlato C, Caraglia M. Erlotinib: early clinical development in brain cancer. Expert Opin Investig Drugs. 2014;23:1027–37.

CAS  Article  Google Scholar 

Li X, Zou H, Brown WT. Genes associated with autism spectrum disorder. Brain Res Bull. 2012;88:543–52.

CAS  Article  Google Scholar 

Boksha IS, Prokhorova TA, Tereshkina EB, Savushkina OK, Burbaeva GS. Protein phosphorylation signaling cascades in autism: the role of mTOR pathway. Biochem Mosc. 2021;86:577–96.

CAS  Article  Google Scholar 

Beilina A, Rudenko IN, Kaganovich A, Civiero L, Chau H, Kalia SK, Kalia LV, Lobbestael E, Chia R, Ndukwe K, Ding J, Nalls MA, International Parkinson’s Disease Genomics Consortium, North American Brain Expression Consortium, Olszewski M, Hauser DN, Kumaran R, Lozano AM, Baekelandt V, Greene LE, Taymans JM, Greggio E, Cookson MR. Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease. Proc Natl Acad Sci USA. 2014;111:2626–31.

CAS  Article  Google Scholar 

Dumitriu A, Pacheco CD, Wilk JB, Strathearn KE, Latourelle JC, Goldwurm S, Pezzoli G, Rochet JC, Lindquist S, Myers RH. Cyclin-G-associated kinase modifies alpha-synuclein expression levels and toxicity in Parkinson’s disease: results from the Gene PD Study. Hum Mol Genet. 2011;20:1478–87.

CAS  Article  Google Scholar 

Umeda A, Meyerholz A, Ungewickell E. Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation. Eur J Cell Biol. 2000;79:336–42.

CAS  Article  Google Scholar