aIntensive Care Unit, Jikei University Hospital, Tokyo, Japan

bAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia

cDepartment of Health Promotion and Human Behaviour, School of Public Health, Kyoto University Graduate School of Medicine, Kyoto, Japan

dDepartment of Critical Care, University of Melbourne

ePreclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, Melbourne

fIntensive Care Unit, Austin Hospital, Heidelberg, Victoria, Australia

Correspondence to Rinaldo Bellomo, AO, Heidelberg, Australia. Tel: +61 3 9496 5992; fax: +61 3 9496 3932; e-mail: [email protected]