Silvia Marino Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, United Kingdom Corresponding author: s.marinoqmul.ac.uk Abstract

Here I discuss the study in this issue of Genes & Development by Youn et al. (pp. 737–751), which describes defined and diverse roles of primary cilia in molecularly distinct medulloblastoma subgroups, highlighting once again the importance of designing subgroup-specific therapeutic approaches for this tumor.