Fridman, N.V., Lin’kova, N.S., Boiko, L.V., and Kakheli, M.A., Effects of peptide bioregulators on structural and functional peculiarities of facial skin in elderly women, Mol. Med., 2021, no. 4, pp. 42–46.

Cavinato, M., Koziel, R., Romani, N., et al., UVB-induced senescence of human dermal fibroblasts involves impairment of proteasome and enhanced autophagic activity, J. Gerontol. A Biol. Sci. Med. Sci., 2017, vol. 72, no. 5, pp. 632–639.

CAS  PubMed  Google Scholar 

Choi, J.W., Lee, J., and Park, Y.I., 7,8-Dihydroxyflavone attenuates TNF-α-induced skin aging in Hs68 human dermal fibroblast cells via down-regulation of the MAPKs/Akt signaling pathways, Biomed. Pharmacother., 2017, vol. 95, pp. 1580–1587.

CAS  Article  Google Scholar 

De Tollenaere, M., Meunier, M., Scandolera, A., et al., Well-aging: a new strategy for skin homeostasis under multi-stressed conditions, J. Cosmet. Dermatol., 2020, vol. 19, no. 2, pp. 444–455.

Article  Google Scholar 

Gęgotek, A., Ambrożewicz, E., Jastrząb, A., et al., Rutin and ascorbic acid cooperation in antioxidant and antiapoptotic effect on human skin keratinocytes and fibroblasts exposed to UVA and UVB radiation, Arch. Dermatol. Res., 2019, vol. 311, no. 3, pp. 203–219.

Article  Google Scholar 

Gravitz, L., Skin, Nature, 2018, vol. 563, no. 7732, p. 83. https://doi.org/10.1038/d41586-018-07428-4

Gromkowska-Kępka, K.J., PuścionJakubik, A., Markiewicz-Żukowska, R., and Socha, K., The impact of ultraviolet radiation on skin photoaging—review of in vitro studies, J. Cosmet. Dermatol., 2021. https://doi.org/10.1111/jocd.14033

Gu, Y., Han, J., Jiang, C., and Zhang, Y., Biomarkers, oxidative stress and autophagy in skin aging, Ageing Res. Rev., 2020, vol. 59, p. 101036. https://doi.org/10.1016/j.arr.2020.101036

CAS  Article  Google Scholar 

Il’ina, T.N., Vinogradova, I.A., Iliukha, V.A., et al., The influences of geroprotectors on age-related changes of antioxidant system in rats liver under different light condition, Adv. Gerontol., 2008, vol. 21, no. 3, pp. 386–393.

PubMed  Google Scholar 

Ivko, O.M., Linkova, N.S., Ilina, A.R., et al., AEDG peptide regulates human circadian rhythms genes expression during pineal gland accelerated aging, Adv. Gerontol., 2020, vol. 33, no. 3, pp. 429–435.

CAS  PubMed  Google Scholar 

Kammeyer, A. and Luiten, R.M., Oxidation events and skin aging, Ageing Res. Rev., 2015, vol. 21, pp. 16–29.

CAS  Article  Google Scholar 

Khavinson, V.Kh., Bondarev, I.E., and Butyugov, A.A., Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells, Bull. Exp. Biol. Med., 2003, vol. 135, no. 6, pp. 590–592.

CAS  Article  Google Scholar 

Khavinson, V.Kh., Lezhava, T.A., Monaselidze, J.R., et al., Peptide epitalon activates chromatin at the old age, Neuro Endocrinol. Lett., 2003, vol. 24, no. 5, pp. 329–333.

CAS  PubMed  Google Scholar 

Khavinson, V.Kh., Linkova, N.S., and Tarnovskaya, S.I., Short peptides regulate gene expression, Bull. Exp. Biol. Med., 2016, vol. 162, no. 2, pp. 288–292.

CAS  Article  Google Scholar 

Khavinson, V.Kh., Pendina, A.A., Efimova, O.A., et al., Effect of peptide AEDG on telomere length and mitotic index of PHA-stimulated human blood lymphocytes, Bull. Exp. Biol. Med., 2019, vol. 168, no. 1, pp. 141–144.

CAS  Article  Google Scholar 

Khavinson, V., Diomede, F., Mironova, E., et al., AEDG peptide (epitalon) stimulates gene expression and protein synthesis during neurogenesis: possible epigenetic mechanism, Molecules, 2020, vol. 25, no. 3, p. 609. https://doi.org/10.3390/molecules25030609

CAS  Article  Google Scholar 

Kim, J., Toda, T., Watanabe, K., et al., Syringaresinol reverses age-related skin atrophy by suppressing FoxO3a-mediated matrix metalloproteinase-2 activation in copper/zinc superoxide dismutase-deficient mice, J. Invest. Dermatol., 2019, vol. 139, no. 3, pp. 648–655.

CAS  Article  Google Scholar 

Kozina, L.S., Arutjunyan, A.V., and Khavinson, V.Kh., Antioxidant properties of geroprotective peptides of the pineal gland, Arch. Gerontol. Geriatr., 2007, vol. 44, suppl. 1, pp. 213–216.

Lephart, E.D., Skin aging and oxidative stress: equol’s anti-aging effects via biochemical and molecular mechanisms, Ageing Res. Rev., 2016, vol. 31, pp. 36–54.

CAS  Article  Google Scholar 

Letsiou, S., Bakea, A., Goff, G.L., et al., Marine fungus Aspergillus chevalieri TM2-S6 extract protects skin fibroblasts from oxidative stress, Mar. Drugs, 2020, vol. 18, no. 9, p. 460. https://doi.org/10.3390/md18090460

CAS  Article  Google Scholar 

Li, Z., Galli, U., Becker, L.E., et al., Sulforaphane protects hearts from early injury after experimental transplantation, Ann. Transplant., 2013, vol. 18, pp. 558–566.

CAS  Article  Google Scholar 

Lone, A.N., Malik, A.T., Naikoo, H.S., Raghu, R.S., and Tasduq, S.A., Trigonelline, a naturally occurring alkaloidal agent protects ultraviolet-B (UV-B) irradiation induced apoptotic cell death in human skin fibroblasts via attenuation of oxidative stress, restoration of cellular calcium homeostasis and prevention of endoplasmic reticulum (ER) stress, J. Photochem. Photobiol., vol. 202, p. 111720. https://doi.org/10.1016/j.jphotobiol.2019.111720

Qian, X., Asad, S.B., Li, J., et al., Link between cardiac function and the antioxidative defense mechanism in aged rats, Biochem. Biophys. Res. Commun., 2019, vol. 513, no. 4, pp. 1100–1105.

CAS  Article  Google Scholar 

Sannasimuthu, A., Kumaresan, V., Anilkumar, S., et al., Design and characterization of a novel Arthrospira platensis glutathione oxido-reductase-derived antioxidant peptide GM15 and its potent anti-cancer activity via caspase-9 mediated apoptosis in oral cancer cells, Free Radical Biol. Med., 2019, vol. 135, pp. 198–209.

CAS  Article  Google Scholar 

Shin, M.H., Lee, S.R., Kim, M.K., et al., Activation of peroxisome proliferator-activated receptor alpha improves aged and UV-irradiated skin by catalase induction, PLoS One, 2016, vol. 11, no. 9. e0162628. https://doi.org/10.1371/journal.pone.0162628

Toshihiro, F., Teruyuki, D., Zeshaan, N.M., et al., Age-associated intracellular superoxide dismutase deficiency potentiates dermal fibroblast dysfunction during wound healing, Exp. Dermatol., 2019, vol. 28, no. 4, pp. 485–492.

Article  Google Scholar 

Xie, L., Pandey, R., Xu, B., et al., Genomic and proteomic profiling of oxidative stress response in human diploid fibroblasts, Biogerontology, 2009, vol. 10, no. 2, pp. 125–151.

CAS  Article  Google Scholar 

Zhang, J.A., Yin, Z., Ma, L.W., et al., The protective effect of baicalin against UVB irradiation induced photoaging: an in vitro and in vivo study, PLoS One, 2014, vol. 9, no. 6. e99703. https://doi.org/10.1371/journal.pone.0099703

Zhong, G., He, Y., Wan, F., et al., Effects of long-term exposure to copper on the KEAP1/NRF2 signaling pathway and MSR-related redox status in the kidneys of rats, Biol. Trace Elem. Res., 2021. https://doi.org/10.1007/s12011-020-02557-2