Dementia and Geriatric Cognitive Disorders

Honjo Y.a,b,c,d,e· Kawasaki I.e· Nagai K.e· Harada S.e· Ogawa N.e

Author affiliations

aMemory Clinic, Kyoto Kaisei Hospital, Kyoto, Japan
bMemory Clinic, Kyoto Miniren Asukai Hospital, Kyoto, Japan
cMemory Clinic, Seika-town National Health Insurance Hospital, Kyoto, Japan
dMemory Clinic, Kyoto Narabigaoka Hospital, Kyoto, Japan
eDepartment of Occupational Therapy, Faculty of Health Sciences, Kyoto Tachibana University, Kyoto, Japan

Dement Geriatr Cogn Disord

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Article / Publication Details

First-Page Preview

Received: April 11, 2022
Accepted: June 14, 2022
Published online: July 12, 2022

Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 4

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: https://www.karger.com/DEM

Abstract

Introduction: Alzheimer’s disease (AD) is the most common cognitive disease, and behavioral and psychological symptoms of dementia (BPSD) can place a heavy burden on families. The presence of these symptoms related to AD is commonly assessed using the Neuropsychiatric Inventory Questionnaire (NPI-Q). This study sought to clarify the relationship between scores on the 12-domain NPI-Q and individual factors in patients with AD. Methods: Participants were 218 new outpatients with AD at five memory clinics. Cognitive function was assessed using the Revised Hasegawa Dementia Scale (HDS-R) and Mini-Mental State Examination (MMSE). We examined which individual factors were associated with the total NPI-Q score and the number of domains. We also examined which domains were associated with the factors identified. Results: A higher total NPI score was significantly associated with lower scores on both cognitive assessments and a longer duration of education. Exhibiting symptoms on a greater number of domains was significantly associated with lower scores on both cognitive assessments, longer duration of education, and advanced age. The nighttime disturbances domain was significantly associated with lower scores on both cognitive assessments and advanced age. The delusions domain was significantly associated with lower education. Conclusions: BPSD may appear more easily with reduced quality of life and ongoing dissatisfaction. Effective individualized services are important for patients with AD, and therefore, we should account for age, cognitive function, and duration of education in the services provided.

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First-Page Preview

Received: April 11, 2022
Accepted: June 14, 2022
Published online: July 12, 2022

Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 4

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: https://www.karger.com/DEM

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