National diabetes statistics: center for disease control division of diabetes translation; 2020 [06/08/2021]. Available from: http://www.cdc.gov/diabetes/statistics. Accessed 6/8/21.

American DA. 14. Diabetes care in the hospital: standards of medical care in diabetes-2018. Diabetes Care. 2018;41(Suppl 1):S144–S51.

Article  Google Scholar 

van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, et al. Intensive insulin therapy in critically ill patients. N Engl J Med. 2001;345(19):1359–67.

Article  PubMed  Google Scholar 

American DA. 15. Diabetes care in the hospital: standards of medical care in diabetes-2021. Diabetes Care. 2021;44(Suppl 1):S211–S20.

Article  Google Scholar 

Clement S, Braithwaite SS, Magee MF, Ahmann A, Smith EP, Schafer RG, et al. Management of diabetes and hyperglycemia in hospitals. Diabetes Care. 2004;27(2):553–91.

Article  PubMed  Google Scholar 

Moghissi ES, Korytkowski MT, DiNardo M, Einhorn D, Hellman R, Hirsch IB, et al. American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Diabetes Care. 2009;32(6):1119–31.

PubMed Central  Article  PubMed  Google Scholar 

Bogun M, Inzucchi SE. Inpatient management of diabetes and hyperglycemia. Clin Ther. 2013;35(5):724–33.

Article  PubMed  Google Scholar 

Cardona S, Gomez PC, Vellanki P, Anzola I, Ramos C, Urrutia MA, et al. Clinical characteristics and outcomes of symptomatic and asymptomatic hypoglycemia in hospitalized patients with diabetes. BMJ Open Diabetes Res Care. 2018;6(1):e000607.

PubMed Central  Article  PubMed  Google Scholar 

Brod M, Christensen T, Thomsen TL, Bushnell DM. The impact of non-severe hypoglycemic events on work productivity and diabetes management. Value Health. 2011;14(5):665–71.

Article  PubMed  Google Scholar 

Umpierrez GE, Klonoff DC. Diabetes technology update: use of insulin pumps and continuous glucose monitoring in the hospital. Diabetes Care. 2018;41(8):1579–89.

CAS  PubMed Central  Article  PubMed  Google Scholar 

Wollersheim T, Engelhardt LJ, Pachulla J, Moergeli R, Koch S, Spies C, et al. Accuracy, reliability, feasibility and nurse acceptance of a subcutaneous continuous glucose management system in critically ill patients: a prospective clinical trial. Ann Intensive Care. 2016;6(1):70.

PubMed Central  Article  PubMed  Google Scholar 

Freestyle Libre 2 Package insert (n.d.) [Available from: https://www.freestyle.abbott/us-en/products/freestyle-libre-2.html. Accessed 6/8/21.

Freestyle Libre 14 day system package insert (n.d.) [Available from: https://www.freestyle.abbott/us-en/products/freestyle-14-day.html. Accessed 6/8/21.

Dexcom G6 Package insert (n.d.) [Available from: https://provider.dexcom.com/products/dexcom-g6-personal-cgm-system. Accessed 6/8/21.

Medtronic MiniMed Guardian Sensor package insert (n.d.) [Available from: https://www.medtronicdiabetes.com/sites/default/files/library/download-library/user-guides/Guardian-Sensor-3-user-guide.pdf. Accessed 6/8/21.

Senseonics Eversense package insert (n.d.) [Available from: https://resources.eversensediabetes.com/resources/hcp. Accessed 6/8/21.

Moghissi ES, Korytkowski MT, DiNardo M, Einhorn D, Hellman R, Hirsch IB, et al. American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Endocr Pract. 2009;15(4):353–69.

Article  PubMed  Google Scholar 

Inoue S, Egi M, Kotani J, Morita K. Accuracy of blood-glucose measurements using glucose meters and arterial blood gas analyzers in critically ill adult patients: systematic review. Crit Care. 2013;17(2):R48.

PubMed Central  Article  PubMed  Google Scholar 

Galindo RJ, Umpierrez GE, Rushakoff RJ, Basu A, Lohnes S, Nichols JH, et al. Continuous glucose monitors and automated insulin dosing systems in the hospital consensus guideline. J Diabetes Sci Technol. 2020;14(6):1035–64. This guideline includes the most up-to-date reccomendations for use of CGM in the inpatient setting

PubMed Central  Article  PubMed  Google Scholar 

Bochicchio GV, Nasraway S, Moore L, Furnary A, Nohra E, Bochicchio K. Results of a multicenter prospective pivotal trial of the first inline continuous glucose monitor in critically ill patients. J Trauma Acute Care Surg. 2017;82(6):1049–54.

Article  PubMed  Google Scholar 

Rijkenberg S, van Steen SC, DeVries JH, van der Voort PHJ. Accuracy and reliability of a subcutaneous continuous glucose monitoring device in critically ill patients. J Clin Monit Comput. 2018;32(5):953–64.

CAS  Article  PubMed  Google Scholar 

Holzinger U, Warszawska J, Kitzberger R, Wewalka M, Miehsler W, Herkner H, et al. Real-time continuous glucose monitoring in critically ill patients: a prospective randomized trial. Diabetes Care. 2010;33(3):467–72.

CAS  Article  PubMed  Google Scholar 

Boom DT, Sechterberger MK, Rijkenberg S, Kreder S, Bosman RJ, Wester JP, et al. Insulin treatment guided by subcutaneous continuous glucose monitoring compared to frequent point-of-care measurement in critically ill patients: a randomized controlled trial. Crit Care. 2014;18(4):453.

PubMed Central  Article  PubMed  Google Scholar 

De Block CE, Gios J, Verheyen N, Manuel-y-Keenoy B, Rogiers P, Jorens PG, et al. Randomized evaluation of glycemic control in the medical intensive care unit using real-time continuous glucose monitoring (REGIMEN Trial). Diabetes Technol Ther. 2015;17(12):889–98.

Article  CAS  PubMed  Google Scholar 

Krinsley JS, Bruns DE, Boyd JC. The impact of measurement frequency on the domains of glycemic control in the critically ill--a Monte Carlo simulation. J Diabetes Sci Technol. 2015;9(2):237–45.

PubMed Central  Article  PubMed  Google Scholar 

Rodriguez LM, Knight RJ, Heptulla RA. Continuous glucose monitoring in subjects after simultaneous pancreas-kidney and kidney-alone transplantation. Diabetes Technol Ther. 2010;12(5):347–51.

CAS  PubMed Central  Article  PubMed  Google Scholar 

Burt MG, Roberts GW, Aguilar-Loza NR, Stranks SN. Brief report: comparison of continuous glucose monitoring and finger-prick blood glucose levels in hospitalized patients administered basal-bolus insulin. Diabetes Technol Ther. 2013;15(3):241–5.

CAS  Article  PubMed  Google Scholar 

Schaupp L, Donsa K, Neubauer KM, Mader JK, Aberer F, Holl B, et al. Taking a closer look--continuous glucose monitoring in non-critically ill hospitalized patients with type 2 diabetes mellitus under basal-bolus insulin therapy. Diabetes Technol Ther. 2015;17(9):611–8.

CAS  Article  PubMed  Google Scholar 

Gomez AM, Umpierrez GE, Munoz OM, Herrera F, Rubio C, Aschner P, et al. Continuous glucose monitoring versus capillary point-of-care testing for inpatient glycemic control in type 2 diabetes patients hospitalized in the general ward and treated with a basal bolus insulin regimen. J Diabetes Sci Technol. 2015;10(2):325–9.

PubMed Central  Article  CAS  PubMed  Google Scholar 

Gu W, Liu Y, Chen Y, Deng W, Ran X, Chen L, et al. Multicentre randomized controlled trial with sensor-augmented pump vs multiple daily injections in hospitalized patients with type 2 diabetes in China: time to reach target glucose. Diabetes Metab. 2017;43(4):359–63.

CAS  Article  PubMed  Google Scholar 

Galindo RJ, Migdal AL, Davis GM, Urrutia MA, Albury B, Zambrano C, et al. Comparison of the freestyle libre pro flash continuous glucose monitoring (CGM) system and point-of-care capillary glucose testing in hospitalized patients with type 2 diabetes treated with basal-bolus insulin regimen. Diabetes Care. 2020;43(11):2730–5.

CAS  PubMed Central  Article  PubMed  Google Scholar 

Davis GM, Spanakis EK, Migdal AL, Singh LG, Albury B, Urrutia MA, et al. Accuracy of Dexcom G6 continuous glucose monitoring in non-critically ill hospitalized patients with diabetes. Diabetes Care. 2021;

Singh LG, Satyarengga M, Marcano I, Scott WH, Pinault LF, Feng Z, et al. Reducing Inpatient hypoglycemia in the general wards using real-time continuous glucose monitoring: the glucose telemetry system, a randomized clinical trial. Diabetes Care. 2020;43(11):2736–43.

CAS  PubMed Central  Article  PubMed  Google Scholar 

Thabit H, Hartnell S, Allen JM, Lake A, Wilinska ME, Ruan Y, et al. Closed-loop insulin delivery in inpatients with type 2 diabetes: a randomised, parallel-group trial. Lancet Diabetes Endocrinol. 2017;5(2):117–24.

CAS  Article  PubMed  Google Scholar 

Fortmann AL, Spierling Bagsic SR, Talavera L, Garcia IM, Sandoval H, Hottinger A, et al. Glucose as the fifth vital sign: a randomized controlled trial of continuous glucose monitoring in a non-ICU hospital setting. Diabetes Care. 2020;43(11):2873–7.

CAS  PubMed Central  Article  PubMed  Google Scholar 

Perez-Guzman MC, Duggan E, Gibanica S, Cardona S, Corujo-Rodriguez A, Faloye A, et al. Continuous glucose monitoring in the operating room and cardiac intensive care unit. Diabetes Care. 2021;44(3):e50–e2.

CAS  PubMed Central  Article  PubMed  Google Scholar 

Nair BG, Dellinger EP, Flum DR, Rooke GA, Hirsch IB. A pilot study of the feasibility and accuracy of inpatient continuous glucose monitoring. Diabetes Care. 2020;43(11):e168–e9.

Article  PubMed  Google Scholar 

Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City Area. JAMA. 2020;323(20):2052–9.

CAS  PubMed Central  Article  PubMed  Google Scholar 

Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708–20.

CAS  Article  PubMed  Google Scholar 

Guo W, Li M, Dong Y, Zhou H, Zhang Z, Tian C, Qin R, Wang H, Shen W, Du K, Zhao L, Fan H, Luo S, Hu D. Diabetes is a risk factor for the progression and prognosis of COVID-19. Diabetes Metab Res Rev. 2020:e3319.

• (FDA) FaDA. Enforcement policy for non-invasive remote monitoring devices used to support patient monitoring during the coronavirus disease 2019 (COVID-19) Public Health Emergency (Revised) 2020 [Available from: https://www.fda.gov/regulatory-information/search-fda-guidance-documents/enforcement-policy-non-invasive-remote-monitoring-devices-used-support-patient-monitoring-during. Accessed 6/8/21. This policy allowed for use of CGM device in the hospital as well as adjunctive monitoring during the COVID-19 pandemic.

Collaborative Open-Access VIrtual Database for COVID-19 In Diabetes 2020 [Available from: www.covidindiabetes.org. Accessed 6/8/21.

Faulds ER BA, Sumner L, Jones L, McNett M, Smetana KS, May CC, Buschur E, Exline MC, Ringel MD, Dungan K. Use of continuous glucose monitor in critically ill COVID-19 patients requiring insulin infusion: an observational study. J Clin Endocrinol Metab 2021;106(10):e4007–16. https://doi.org/10.1210/clinem/dgab409.

Davis GM, Faulds E, Walker T, Vigliotti D, Rabinovich M, Hester J, et al. Remote continuous glucose monitoring with a computerized insulin infusion protocol for critically ill patients in a COVID-19 medical ICU: proof of concept. Diabetes Care. 2021;44(4):1055–8.

CAS  PubMed Central  Article  PubMed  Google Scholar 

Faulds ER, Jones L, McNett M, Smetana KS, May CC, Sumner L, et al. Facilitators and barriers to nursing implementation of continuous glucose monitoring (CGM) in critically ill patients with COVID-19. Endocr Pract. 2021;27(4):354–61.