The Role of Oral Microbiota in Chronic Obstructive Pulmonary Disease

Wen S.a,b· Zhang Z.a,b· Ouyang Y.a,b· Liu J.a,b· Liang Z.a,b· Pi Y.a,b· Su Z.a,b· Chen D.a,b· Guo L.a,b· Jiang Q.a,b· Yang L.a,b· Wang Y.a,c

Author affiliations

aGuangzhou Medical University, Guangzhou, China
bDepartment of Endodontics, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou, China
cGuangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Diseases, Guangzhou, China

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Article / Publication Details

First-Page Preview

Abstract of Review

Received: January 21, 2022
Accepted: June 02, 2022
Published online: July 05, 2022

Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 0

ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)

For additional information: https://www.karger.com/RES

Abstract

Studies have shown that oral microbiota dysbiosis affects patients’ lung function, promoting the development and acute exacerbation of chronic obstructive pulmonary disease (COPD). In this paper, we review the mechanisms potentially linking COPD with periodontitis. Oral microbiota enters the respiratory system through clinical microaspiration to aggravate lung microbiota dysbiosis and induce lung injury by entering the respiratory tract directly. Appropriate interventions for dysbiosis such as periodontal therapy or oral microbial transplantation may prevent the progression of COPD.

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First-Page Preview

Abstract of Review

Received: January 21, 2022
Accepted: June 02, 2022
Published online: July 05, 2022

Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 0

ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)

For additional information: https://www.karger.com/RES

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