Mechanisms of Blood pH Changes in Venovenous Extracorporeal Membrane Systems: Roles of Hemoglobin-Ion Binding and Donnan Equilibrium

From the Department of Pharmacology, Physiology and Neuroscience, University of South Carolina, Columbia, South Carolina.

Submitted for consideration March 2021; accepted for publication in revised form September 2021.

Disclosure: The authors have no conflicts of interest to report.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text, and links to the digital files are provided in the HTML and PDF versions of this article on the journal’s Web site (www.asaiojournal.com).

Correspondence: Matthew B. Wolf, PhD, Department of Pharmacology, Physiology and Neuroscience, University of South Carolina, 4981 Glen Cove Dr, Southport, NC. Email: [email protected]

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