∗Department of Surgery, Division of Trauma and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, Illinois

†Driskill Graduate Program in Life Science, Northwestern University Feinberg School of Medicine, Chicago, Illinois

‡Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois

§Center for Translational Pain Research, Northwestern University Feinberg School of Medicine, Chicago, Illinois

Address reprint requests to Booker T. Davis, IV, PhD, MS, 240 E Huron Street, Chicago, Illinois 60611. E-mail: [email protected]

Received 29 September, 2021

Revised 19 October, 2021

Accepted 15 March, 2022

NIH Grant 1R01GM130662 and NIH Grant 1R01GM130662 - S1.

Ethical Approval and Consent to participate: This article does not contain any studies with human participants. All applicable international, national, and/or institutional guidelines for the care and use of animals were followed. Animals were treated and cared for in accordance with the National Institutes of Health Guidelines for the Use of Laboratory Animals. The Northwestern University Institutional Animal Care and Use Committee approved the experimental protocol.

Consent for publication: All authors of the manuscript have read and agreed to its content and are accountable for all aspects of the accuracy and integrity of the manuscript in accordance with ICMJE criteria. This article is original, has not already been published in a journal, and is not currently under consideration by another journal

The authors report no conflict(s) of interest.

The data that support the findings in this manuscript are available from the corresponding author upon request. The 16S rRNA gene data have been deposited to the Illumina Basespace data repository with the following dataset identifier: “Project MINI667_Steve-Schwulst_Brooker-Davis_38696”.

Reviewer link: https://basespace.illumina.com/projects/286888607

he data that support the findings in this manuscript are available from the corresponding author upon request. The 16S rRNA gene data have been deposited to the Illumina Basespace data repository with the following dataset identifier: “Project MINI667_Steve-Schwulst_Brooker-Davis_38696”.

Reviewer link: https://basespace.illumina.com/projects/286888607

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