Preoperative Risk Factors and Prognostic Impact of Postoperative Complications Associated with Total Gastrectomy

Nakazawa N. · Sohda M. · Yamaguchi A. · Watanabe T. · Saito H. · Ubukata Y. · Kuriyama K. · Sano A. · Sakai M. · Ogawa H. · Shirabe K. · Saeki H.

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Department of General Surgical Science, Gunma University Graduate School of Medicine, Maebashi, Japan

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Article / Publication Details

First-Page Preview

Abstract of Research Article

Received: March 01, 2022
Accepted: May 19, 2022
Published online: June 20, 2022

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 4

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: https://www.karger.com/DIG

Abstract

Introduction: We evaluated the risk factors for patients with gastric cancer (GC) undergoing total gastrectomy (TG) that predict postoperative complications, including anastomotic leakage, postoperative pneumonia, and heart disease. Methods: We collected 106 patients who received TG for GC between May 2009 and May 2017 at Gunma University Graduate School of Medicine, including clinicopathologic, surgical, postoperative complication, laboratory test, and physiologic test data. Results: Of 106 patients, 92 (86.8%) had no complications, and 14 (13.2%) had complications. Univariate analyses revealed that a high American Society of Anaesthesiologists physical status (ASA-PS) and neutrophil-lymphocyte ratio (NLR) of ≥3.5 significantly correlated with postoperative complications. Multivariate analyses showed that high ASA-PS was an independent prognostic factor of postoperative complications. The cancer recurrence rate was 34.8% in the noncomplication group and 71.4% in the complication group. Conclusion: Patients with postoperative complications are prone to recurrence and poor prognosis. For patients with high-risk GC with poor ASA-PS and high NLR, more thorough perioperative management is essential.

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First-Page Preview

Abstract of Research Article

Received: March 01, 2022
Accepted: May 19, 2022
Published online: June 20, 2022

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 4

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: https://www.karger.com/DIG

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