Neonatal Infections: Insights from a Multicenter Longitudinal Research Collaborative

Elsevier

Available online 10 June 2022, 151637

Seminars in PerinatologyAbstract

For more than 30 years, the Neonatal Research Network (NRN) has conducted studies addressing the epidemiology of neonatal infections, including incidence, microbiology, maternal and neonatal risk factors, associated clinical findings, and outcomes. These studies have provided clinicians and policymakers critical data needed to inform national guidance for infection risk assessment and support daily practice. Further, NRN studies have prompted research into optimal approaches to infection diagnosis, treatment, and antimicrobial stewardship. In this article, we summarize the key findings of NRN infection-related studies, with an emphasis on those published in 2000 or later.

AbbreviationsBPD

Bronchopulmonary dysplasia

CDC

Centers for Disease Control and Prevention

CoNS

Coagulase-negative staphylococci

ELBW

Extremely low birth weight

MRSA

Methicillin-resistant Staphylococcus aureus

MSSA

Methicillin-susceptible Staphylococcus aureus

NDI

Neurodevelopmental impairment

NEC

Necrotizing enterocolitis

NICHD

Eunice Kennedy Shriver National Institute of Child Health and Human Development

NRN

Neonatal Research Network

VLBW

Very low birth weight

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