Overview of the Neonatal Research Network: History, Contributions, Challenges, and Future

BPCA, Best Pharmaceuticals for Children Act

BPD, Bronchopulmonary dysplasia

CDC, Centers for Disease Control and Prevention

CPAP, Continuous positive airway pressure

ECMO, Extra-corporeal membrane oxygenation

FDA, U.S. Food and Drug Administration

GDB, Generic Database study

HEAL, Helping to End Addiction Long-term initiative

HIE, Hypoxic-ischemic encephalopathy

iNO, Inhaled nitric oxide

ISPCTN, Idea States Pediatric Clinical Trials Network

MoCHA, Moderately Preterm Infants with Caffeine at Home for Apnea

NDI, Neurodevelopmental impairment

NEC, Necrotizing enterocolitis

NEST, Necrotizing Enterocolitis Surgery Trial

NHLBI, National Heart, Lung, and Blood Institute

NICHD, Eunice Kennedy Shriver National Institute of Child Health and Human Development

NICU, Neonatal intensive care unit

NIDA, National Institute for Drug Abuse

NIH, National Institutes of Health

NEI, National Eye Institute

NINDS, National Institute of Neurologic Disorders and Stroke

NINOS, Neonatal Inhaled Nitric Oxide Study

NRN, Neonatal Research Network

OHRP, Office for Human Research Protections

PGE1, Prostaglandin E1

RCT, Randomized controlled trial

ROP, Retinopathy of prematurity

SAVE, Randomized Trial of Minimal Ventilator Support and Early Corticosteroid Therapy to Increase Survival Without Chronic Lung Disease in Extremely-Low-Birth-Weight Infants

SIP, Spontaneous intestinal perforation

SUPPORT, Surfactant, Positive Pressure, and Oxygenation Randomized Trial

TOP, Transfusion of Prematures trial

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