Maris, J.M., Hogarty, M.D., Bagatell, R., & Cohn, S.L. (2007). Neuroblastoma. Lancet (London, England), 369(9579), 2106–2120. https://doi.org/10.1016/S0140-6736(07)60983-0
Thiele, C.J. (1991). Biology of pediatric peripheral neuroectodermal tumors. Cancer metastasis reviews, 10(4), 311–319. https://doi.org/10.1007/BF00554793
CAS Article PubMed Google Scholar
Pieraccioli, M., Nicolai, S., Pitolli, C., Agostini, M., Antonov, A., Malewicz, M., & Melino, G. (2018). ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America, 115(28), 7356–7361. https://doi.org/10.1073/pnas.1801435115
CAS Article PubMed PubMed Central Google Scholar
Amelio, I., Bertolo, R., Bove, P., Candi, E., Chiocchi, M., Cipriani, C., & Melino, G. (2020). Cancer predictive studies. Biology direct, 15(1), 18. https://doi.org/10.1186/s13062-020-00274-3
Nicolai, S., Pieraccioli, M., Peschiaroli, A., Melino, G., & Raschellà, G. (2015). Neuroblastoma: Oncogenic mechanisms and therapeutic exploitation of necroptosis. Cell death & disease, 6, e2010. https://doi.org/10.1038/cddis.2015.354
Molenaar, J. J., Koster, J., Zwijnenburg, D. A., van Sluis, P., Valentijn, L. J., van der Ploeg, I., & Versteeg, R. (2012). Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. Nature, 483(7391), 589–593. https://doi.org/10.1038/nature10910
CAS Article PubMed Google Scholar
Mossé, Y. P., Laudenslager, M., Longo, L., Cole, K. A., Wood, A., Attiyeh, E. F., & Maris, J. M. (2008). Identification of ALK as a major familial neuroblastoma predisposition gene. Nature, 455(7215), 930–935. https://doi.org/10.1038/nature07261
CAS Article PubMed PubMed Central Google Scholar
Cohn, S. L., Pearson, A. D. J., London, W. B., Monclair, T., Ambros, P. F., Brodeur, G. M., Task, I. N. R. G., & Force. (2009). The International Neuroblastoma Risk Group (INRG) classification system: An INRG Task Force report. Journal of clinical oncology: Official journal of the American Society of Clinical Oncology, 27(2), 289–297. https://doi.org/10.1200/JCO.2008.16.6785
Ragupathi, G., Livingston, P. O., Hood, C., Gathuru, J., Krown, S. E., Chapman, P. B., & Hwu, W.-J. (2003). Consistent antibody response against ganglioside GD2 induced in patients with melanoma by a GD2 lactone-keyhole limpet hemocyanin conjugate vaccine plus immunological adjuvant QS-21. Clinical cancer research: An official journal of the American Association for Cancer Research, 9(14), 5214–5220.
Billon, N., Terrinoni, A., Jolicoeur, C., McCarthy, A., Richardson, W. D., Melino, G., & Raff, M. (2004). Roles for p53 and p73 during oligodendrocyte development. Development (Cambridge, England), 131(6), 1211–1220. https://doi.org/10.1242/dev.01035
de Laurenzi, V., & Melino, G. (2000). Evolution of functions within the p53/p63/p73 family. Annals of the New York Academy of Sciences, 926, 90–100. https://doi.org/10.1111/j.1749-6632.2000.tb05602.x
Bellomaria, A., Barbato, G., Melino, G., Paci, M., & Melino, S. (2010). Recognition of p63 by the E3 ligase ITCH: Effect of an ectodermal dysplasia mutant. Cell cycle (Georgetown, Tex.), 9(18), 3730–9.
Candi, E., Terrinoni, A., Rufini, A., Chikh, A., Lena, A. M., Suzuki, Y., & Melino, G. (2006). p63 is upstream of IKK alpha in epidermal development. Journal of cell science, 119(Pt 22), 4617–4622. https://doi.org/10.1242/jcs.03265
CAS Article PubMed Google Scholar
Candi, E., Cipollone, R., di Val, R., Cervo, P., Gonfloni, S., Melino, G., & Knight, R. (2008). p63 in epithelial development. Cellular and molecular life sciences: CMLS, 65(20), 3126–3133. https://doi.org/10.1007/s00018-008-8119-x
CAS Article PubMed Google Scholar
Candi, E., Agostini, M., Melino, G., & Bernassola, F. (2014). How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: Regulators and effectors. Human mutation, 35(6), 702–714. https://doi.org/10.1002/humu.22523
CAS Article PubMed Google Scholar
Agostini, M., Tucci, P., Killick, R., Candi, E., Sayan, B. S., di Val, R., Cervo, P., & Melino, G. (2011). Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets. Proceedings of the National Academy of Sciences of the United States of America, 108(52), 21093–21098. https://doi.org/10.1073/pnas.1112061109
Article PubMed PubMed Central Google Scholar
Velletri, T., Romeo, F., Tucci, P., Peschiaroli, A., Annicchiarico-Petruzzelli, M., Niklison-Chirou, M. V., Agostini, M. (2013). GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation. Cell cycle (Georgetown, Tex.), 12(22), 3564–73. https://doi.org/10.4161/cc.26771
Tomasini, R., Tsuchihara, K., Tsuda, C., Lau, S. K., Wilhelm, M., Rufini, A., & Mak, T. W. (2009). TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proceedings of the National Academy of Sciences of the United States of America, 106(3), 797–802. https://doi.org/10.1073/pnas.0812096106
Article PubMed PubMed Central Google Scholar
Amelio, I., & Melino, G. (2015). The p53 family and the hypoxia-inducible factors (HIFs): Determinants of cancer progression. Trends in biochemical sciences, 40(8), 425–434. https://doi.org/10.1016/j.tibs.2015.04.007
CAS Article PubMed Google Scholar
Nepravishta, R., Sabelli, R., Iorio, E., Micheli, L., Paci, M., & Melino, S. (2012). Oxidative species and S-glutathionyl conjugates in the apoptosis induction by allyl thiosulfate. The FEBS journal, 279(1), 154–167. https://doi.org/10.1111/j.1742-4658.2011.08407.x
CAS Article PubMed Google Scholar
Mauretti, A., Neri, A., Kossover, O., Seliktar, D., di Nardo, P., & Melino, S. (2016). Design of a novel composite H2 S-releasing hydrogel for cardiac tissue repair. Macromolecular bioscience, 16(6), 847–858. https://doi.org/10.1002/mabi.201500430
CAS Article PubMed Google Scholar
Hattori, T., Takahashi, Y., Chen, L., Tang, Z., Wills, C. A., Liang, X., & Wang, H.-G. (2021). Targeting the ESCRT-III component CHMP2A for noncanonical caspase-8 activation on autophagosomal membranes. Cell death and differentiation, 28(2), 657–670. https://doi.org/10.1038/s41418-020-00610-0
CAS Article PubMed Google Scholar
Brodeur, G. M., Seeger, R. C., Schwab, M., Varmus, H. E., & Bishop, J. M. (1984). Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science (New York, N.Y.), 224(4653), 1121–4. https://doi.org/10.1126/science.6719137
Dang, C., & v, Reddy, E. P., Shokat, K. M., & Soucek, L. (2017). Drugging the “undruggable” cancer targets. Nature reviews. Cancer, 17(8), 502–508. https://doi.org/10.1038/nrc.2017.36
CAS Article PubMed PubMed Central Google Scholar
Gouw, A. M., Margulis, K., Liu, N. S., Raman, S. J., Mancuso, A., Toal, G. G., & Felsher, D. W. (2019). The MYC oncogene cooperates with sterol-regulated element-binding protein to regulate lipogenesis essential for neoplastic growth. Cell metabolism, 30(3), 556-572.e5. https://doi.org/10.1016/j.cmet.2019.07.012
CAS Article PubMed PubMed Central Google Scholar
DeBerardinis, R. J., & Chandel, N. S. (2016). Fundamentals of cancer metabolism. Science advances, 2(5), e1600200. https://doi.org/10.1126/sciadv.1600200
CAS Article PubMed Google Scholar
Lindner, A. U., Salvucci, M., McDonough, E., Cho, S., Stachtea, X., O’Connell, E. P., & Prehn, J. H. M. (2022). An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution. Cell death and differentiation, 29(4), 806–817. https://doi.org/10.1038/s41418-021-00895-9
CAS Article PubMed Google Scholar
Rosa, N., Ivanova, H., Wagner, L. E., Kale, J., la Rovere, R., Welkenhuyzen, K., & Bultynck, G. (2022). Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis. Cell death and differentiation, 29(4), 788–805. https://doi.org/10.1038/s41418-021-00894-w
CAS Article PubMed Google Scholar
Humpton, T. J., Hall, H., Kiourtis, C., Nixon, C., Clark, W., Hedley, A., & Vousden, K. H. (2022). p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4. Cell death and differentiation, 29(3), 514–526. https://doi.org/10.1038/s41418-021-00871-3
CAS Article PubMed Google Scholar
Fiorillo, M., Scatena, C., Naccarato, A. G., Sotgia, F., & Lisanti, M. P. (2021). Bedaquiline, an FDA-approved drug, inhibits mitochondrial ATP production and metastasis in vivo, by targeting the gamma subunit (ATP5F1C) of the ATP synthase. Cell death and differentiation, 28(9), 2797–2817. https://doi.org/10.1038/s41418-021-00788-x
CAS Article PubMed PubMed Central Google Scholar
Shulkin, B. L., Mitchell, D. S., Ungar, D. R., Prakash, D., Dole, M. G., Castle, V. P., & Hutchinson, R. J. (1995). Neoplasms in a pediatric population: 2-[F-18]-fluoro-2-deoxy-D-glucose PET studies. Radiology, 194(2), 495–500. https://doi.org/10.1148/radiology.194.2.7824731
CAS Article PubMed Google Scholar
Levy, A. G., Zage, P. E., Akers, L. J., Ghisoli, M. L., Chen, Z., Fang, W., & Zweidler-McKay, P. A. (2012). The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma. Investigational new drugs, 30(1), 191–199. https://doi.org/10.1007/s10637-010-9551-y
CAS Article PubMed Google Scholar
White, P. S., Thompson, P. M., Seifried, B. A., Sulman, E. P., Jensen, S. J., Guo, C., & Brodeur, G. M. (2001). Detailed molecular analysis of 1p36 in neuroblastoma. Medical and pediatric oncology, 36(1), 37–41. https://doi.org/10.1002/1096-911X(20010101)36:1%3c37::AID-MPO1010%3e3.0.CO;2-L
CAS Article PubMed Google Scholar
King, A., Selak, M. A., & Gottlieb, E. (2006). Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer. Oncogene, 25(34), 4675–4682. https://doi.org/10.1038/sj.onc.1209594
CAS Article PubMed Google Scholar
Feichtinger, R. G., Zimmermann, F., Mayr, J. A., Neureiter, D., Hauser-Kronberger, C., Schilling, F. H., & Kofler, B. (2010). Low aerobic mitochondrial energy metabolism in poorly- or undifferentiated neuroblastoma. BMC Cancer, 10, 149. https://doi.org/10.1186/1471-2407-10-149
CAS Article PubMed PubMed Central Google Scholar
Astuti, D., Morris, M., Krona, C., Abel, F., Gentle, D., Martinsson, T., & Maher, E. R. (2004). Investigation of the role of SDHB inactivation in sporadic phaeochromocytoma and neuroblastoma. British journal of cancer, 91(10), 1835–1841. https://doi.org/10.1038/sj.bjc.6602202
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