Combined pre- and post-capillary pulmonary hypertension in left heart disease

Hassoun PM (2021) Pulmonary arterial hypertension. N Engl J Med 385:2361–2376. https://doi.org/10.1056/NEJMra2000348

CAS  Article  PubMed  Google Scholar 

Rosenkranz S, Gibbs JSR, Wachter R et al (2016) Left ventricular heart failure and pulmonary hypertension. Eur Heart J 37:942–954. https://doi.org/10.1093/eurheartj/ehv512

Article  PubMed  Google Scholar 

Dixon DD, Trivedi A, Shah SJ (2016) Combined post- and pre-capillary pulmonary hypertension in heart failure with preserved ejection fraction. Heart Fail Rev 21:285–297. https://doi.org/10.1007/s10741-015-9523-6

Article  PubMed  Google Scholar 

Rosenkranz S, Kramer T, Gerhardt F et al (2019) Pulmonary hypertension in HFpEF and HFrEF: pathophysiology, diagnosis, treatment approaches. Herz 44(6):483–490. https://doi.org/10.1007/s00059-019-4831-6

CAS  Article  PubMed  Google Scholar 

Gorter TM, Hoendermis ES, van Veldhuisen DJ et al (2016) Right ventricular dysfunction in heart failure with preserved ejection fraction: a systematic review and meta-analysis. Eur J Heart Fail 18:1472. https://doi.org/10.1002/ejhf.630

Article  PubMed  Google Scholar 

Galiè N, Humbert M, Vachiery J-L et al (2016) 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J 37(1):67–119. https://doi.org/10.1093/eurheartj/ehv317

Article  PubMed  Google Scholar 

Maron BA, Hess E, Maddox TM et al (2016) Association of borderline pulmonary hypertension with mortality and hospitalization in a large patient cohort: insights from the veterans affair clinical assessment, reporting and tracking program. Circulation 133:1240–1248. https://doi.org/10.1161/CIRCULATIONAHA.115.020207

Article  PubMed  PubMed Central  Google Scholar 

Kolte D, Lakshmanan S, Jankowich MD, Brittain EL, Maron BA, Choudhary G (2018) Mild pulmonary hypertension is associated with increased mortality: a systematic review and meta-analysis. J Am Heart Assoc 7:e009729. https://doi.org/10.1161/JAHA.118.009729

Article  PubMed  PubMed Central  Google Scholar 

Yaghi S, Novikov A, Trandafirescu T (2020) Clinical update on pulmonary hypertension. J Investig Med 68(4):821–827. https://doi.org/10.1136/jim-2020-001291

Article  PubMed  PubMed Central  Google Scholar 

Palazzini M, Dardi F, Manes A et al (2018) Pulmonary hypertension due to left heart disease: analysis of survival according to the haemodynamic classification of the 2015 ESC/ERS guidelines and insights for future changes. Eur J Heart Fail 20:248–255. https://doi.org/10.1002/ejhf.860

Article  PubMed  Google Scholar 

Vachiéry JL, Tedford RJ, Rosenkranz S et al (2019) Pulmonary hypertension due to left heart disease. Eur Respir J. https://doi.org/10.1183/13993003.01897-2018

Article  PubMed  PubMed Central  Google Scholar 

Bradley AM, Gabor K, Anjali V et al (2020) Cardiopulmonary hemodynamics in pulmonary hypertension and heart failure: JACC review topic of the week. J Am Coll Cardiol 76(22):2671–2681. https://doi.org/10.1016/j.jacc.2020.10.007

Article  Google Scholar 

Sugimoto K, Yoshihisa A et al (2020) Significance of pulmonary vascular resistance and diastolic pressure gradient on the new definition of combined post-capillary pulmonary hypertension. Int Heart J 61:301–307. https://doi.org/10.1536/ihj.19-476

Article  PubMed  Google Scholar 

Maron BA, Kovacs G, Vaidya A et al (2020) Cardiopulmonary hemodynamics in pulmonary hypertension and heart failure. J Am Coll Cardiol 76:2671–2681. https://doi.org/10.1016/j.jacc.2020.10.007

Article  PubMed  PubMed Central  Google Scholar 

Moraes DL, Colucci WS, Givertz MM (2000) Secondary pulmonary hypertension in chronic heart failure: the role of the endothelium in pathophysiology and management. Circulation 102(14):1718–1723. https://doi.org/10.1161/01.CIR.102.14.1718

CAS  Article  PubMed  Google Scholar 

Azarbar S, Dupuis J (2014) Lung capillary injury and repair in left heart disease: a new target for therapy? Clin Sci 127(2):65–76. https://doi.org/10.1042/CS20130296]

CAS  Article  Google Scholar 

Saouti N, Westerhof N, Postmus PE, Vonk-Noordegraaf A (2010) The arterial load in pulmonary hypertension. Eur Respir Rev 19(117):197–203. https://doi.org/10.1183/09059180.00002210

CAS  Article  PubMed  Google Scholar 

Chen Y, Guo H, Xu D et al (2012) Left ventricular failure produces profound lung remodeling and pulmonary hypertension in mice: heart failure causes severe lung disease. Hypertension 59(6):1170–1178. https://doi.org/10.1161/HYPERTENSIONAHA.111.186072

CAS  Article  PubMed  Google Scholar 

Yehuda OB, Rubin LJ (2016) Pulmonary hypertension overlap syndrome, a real entity? JACC 68(4):379–81380. https://doi.org/10.1016/j.jacc2016.05.045

Article  Google Scholar 

Assad TR, Hemnes AR, Larkin EK et al (2016) Clinical and biological insights into combined post- and pre-capillary pulmonary hypertension. J Am Coll Cardiol 68(23):2525–2536. https://doi.org/10.1016/j.jacc.2016.09.942

Article  PubMed  PubMed Central  Google Scholar 

Pugh ME, Robbins IM, Rice TW, West J, Newman JH, Hemnes AR (2011) Unrecognized glucose intolerance is common in pulmonary arterial hypertension. J Hear Lung Transplant 30(8):904–911. https://doi.org/10.1016/j.healun.2011.02.016

Article  Google Scholar 

West J, Niswender KD, Johnson JA et al (2013) A potential role for insulin resistance in experimental pulmonary hypertension. Eur Respir J 41(4):861–871. https://doi.org/10.1183/09031936.00030312

CAS  Article  PubMed  Google Scholar 

Hyman L, Howard L, Hauth TA et al (1989) Endothelin produces pulmonary vasoconstriction and systemic vasodilatation. J Appl Physiol 66(2):1008–1012. https://doi.org/10.1152/jappl.1989.66.2.1008

Article  PubMed  Google Scholar 

Hassoun P, Thappa V, Landman M et al (1992) endothelin 1: mitogenic activity on pulmonary artery smooth muscle cells and release from hypoxic endothelial cells. Proc Soc Exp Biol Med 199(2):165–170. https://doi.org/10.3181/00379727-199-43342

CAS  Article  PubMed  Google Scholar 

Van Duin RWB, Stam K, Cai Z et al (2019) Transition from post capillary pulmonary hypertension to combined pre- and post-capillary pulmonary hypertension in swine: a key role for endothelin. J Physiol. https://doi.org/10.1113/JP275987

Article  PubMed  Google Scholar 

Meoli DF, Ru SuY, Brittain EV, Robbins IV et al (2018) the transpulmonary ratio of endothelin 1 is elevated in patients with preserved left ventricular ejection fraction and combined pre- and post-capillary pulmonary hypertension. Pulm Circ 8(1):1–8. https://doi.org/10.1177/2045893217745019

CAS  Article  Google Scholar 

Yang J, Li X, Morrel NW (2014) ID protein in the vasculature: from molecular biology to cardiopulmonary medicine. Cardiovasc Res 104:388–398. https://doi.org/10.1093/cvr/cvu215

CAS  Article  PubMed  Google Scholar 

Morty RE et al (2007) Dysregulated bone morphogenetic protein signalling in monocrotaline-induced pulmonary arterial hypertension. Arterioscler Thromb Vasc Biol 27:1072–1078. https://doi.org/10.1161/ATVBAHA.107.141200

CAS  Article  PubMed  Google Scholar 

Yang Y et al (2013) ID proteins are critical downstream effectors of BMP signalling in human pulmonary arterial smooth muscle cell. Am J Physiol Lung Cell Mol Physiol 305:312–321. https://doi.org/10.1152/ajplung.00054.2013

CAS  Article  Google Scholar 

Arwood MJ, Vahabi N, Lteif C et al (2019) Transcriptome-wide analysis associates ID2 expression with combined pre- and post-capillary pulmonary hypertension. Sci Rep 9(1):19572. https://doi.org/10.1038/s41598-019-55700-y

CAS  Article  PubMed  PubMed Central  Google Scholar 

Miller WL, Grill DE, Borlaug BA (2013) Clinical features, hemodynamics, and outcomes of pulmonary hypertension due to chronic heart failure with reduced ejection fraction: pulmonary hypertension and heart failure. JACC Hear Fail 1(4):290–299. https://doi.org/10.1016/j.jchf.2013.05.001

Article  Google Scholar 

Leopold JA (2016) Biological phenotyping of combined post-capillary and pre-capillary pulmonary hypertension: focus on pulmonary vascular remodeling. J Am Coll Cardiol 68(23):2537–2539. https://doi.org/10.1016/j.jacc.2016.10.013

Article  PubMed  PubMed Central  Google Scholar 

Opitz CF, Hoeper MM, Gibbs JSR et al (2016) Pre-capillary, combined, and post-capillary pulmonary hypertension: a pathophysiological continuum. J Am Coll Cardiol 68:368–378. https://doi.org/10.1016/j.jacc.2016.05.047

Article  PubMed  Google Scholar 

Ryan JJ, Rich JD, Thiruvoipati T, Swamy R, Kim GH, Rich S (2012) Current practice for determining pulmonary capillary wedge pressure predisposes to serious errors in the classification of patients with pulmonary hypertension. Am Heart J 163(4):589–594. https://doi.org/10.1016/j.ahj.2012.01.024

Article  PubMed  Google Scholar 

Robbins IM, Hemnes AR, Pugh ME et al (2014) High prevalence of occult pulmonary venous hypertension revealed by fluid challenge in pulmonary hypertension. Circ Hear Fail 7(1):116–122. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000468

Article  Google Scholar 

Fujimoto N, Borlaug BA, Lewis GD et al (2013) Hemodynamic responses to rapid saline loading: the impact of age, sex, and heart failure. Circulation 127(1):55–62. https://doi.org/10.1161/CIRCULATIONAHA.112.111302

CAS  Article  PubMed  Google Scholar 

Pellegrini P, Rossi A et al (2014) Prognostic relevance of pulmonary arterial compliance in patients with chronic heart failure. Chest J 5:1064–1070. https://doi.org/10.1378/chest.13-1510

Article  Google Scholar 

Ghio S, Schirinzi S, Pica S (2015) Pulmonary arterial compliance: how and why should we measure it? Glob Cardiol Sci Pract 2015(4):58. https://doi.org/10.5339/gcsp.2015.58

Article  PubMed  PubMed Central  Google Scholar 

Ghio S, Crimi G, Pica S et al (2017) Persistent abnormalities in pulmonary arterial compliance after heart transplantation in patients with combined post-capillary and pre-capillary pulmonary hypertension. PLoS ONE 12(11):e0188383. https://doi.org/10.1371/journal.pone.0188383

CAS  Article  PubMed  PubMed Central 

留言 (0)

沒有登入
gif