Innovative therapeutics in acromegaly

Elsevier

Available online 27 May 2022, 101679

Best Practice & Research Clinical Endocrinology & MetabolismAbstract

Acromegaly is a systemic disease associated with increased morbidity and mortality that can be prevented with adequate disease control. Three modalities of treatment (surgery, medical treatment, and radiotherapy) are available; however, a significant proportion of patients still maintain disease activity despite treatment. Therefore, there is a need for innovations in the treatment of acromegaly that include changes in the current trial and error approach and the development of new drugs. In this review, we summarize the recent innovations in the treatment of acromegaly and address the future perspectives in this field.

Keywords

acromegaly

novel treatments

medical treatment

somatostatin receptor ligands

precision medicine

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