Hu H, Cui Y, Yang Y. Circuits and functions of the lateral habenula in health and in disease. Nat Rev Neurosci. 2020;21(5):277–95.

CAS  Article  Google Scholar 

Metzger M, Souza R, Lima LB, Bueno D, Gonçalves L, Sego C, et al. Habenular connections with the dopaminergic and serotonergic system and their role in stress-related psychiatric disorders. Eur J Neurosci. 2021;53(1):65–88.

Article  Google Scholar 

Sartorius A, Henn FA. Deep brain stimulation of the lateral habenula in treatment resistant major depression. Med Hypotheses. 2007;69(6):1305–8.

Article  Google Scholar 

Zanos P, Gould TD. Mechanisms of ketamine action as an antidepressant. Mol Psychiatry. 2018;23(4):801–11.

CAS  Article  Google Scholar 

Qiao D, Zhang A, Sun N, Yang C, Li J, Zhao T, et al. Altered static and dynamic functional connectivity of habenula associated with suicidal ideation in first-episode, drug-naïve patients with major depressive disorder. Front Psychiatry. 2020;11:608197.

Article  Google Scholar 

Han S, Yang SH, Kim JY, Mo S, Yang E, Song KM, et al. Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior. Sci Rep. 2017;7(1):900.

Article  Google Scholar 

Gutiérrez-Sacristán A, Grosdidier S, Valverde O, Torrens M, Bravo À, Piñero J, et al. PsyGeNET: a knowledge platform on psychiatric disorders and their genes. Bioinformatics. 2015;31(18):3075–7.

Article  Google Scholar 

Hashikawa Y, Hashikawa K, Rossi MA, Basiri ML, Liu Y, Johnston NL, et al. Transcriptional and spatial resolution of cell types in the mammalian habenula. Neuron. 2020;106(5):743-758.e5.

CAS  Article  Google Scholar 

Munji RN, Soung AL, Weiner GA, Sohet F, Semple BD, Trivedi A, et al. Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood–brain barrier dysfunction module. Nat Neurosci. 2019;22(11):1892–902.

CAS  Article  Google Scholar 

Lilly AJ, Lacaud G, Kouskoff V. SOXF transcription factors in cardiovascular development. Semin Cell Dev Biol. 2017;63:50–7.

CAS  Article  Google Scholar 

Corada M, Orsenigo F, Bhat GP, Conze LL, Breviario F, Cunha SI, et al. Fine-tuning of Sox17 and canonical Wnt coordinates the permeability properties of the blood–brain barrier. Circ Res. 2019;124(4):511–25.

CAS  Article  Google Scholar 

Chavez JC, Baranova O, Lin J, Pichiule P. The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes. J Neurosci. 2006;26(37):9471–81.

CAS  Article  Google Scholar 

Empana JP, Boutouyrie P, Lemogne C, Jouven X, van Sloten TT. Microvascular contribution to late-onset depression: mechanisms, current evidence, association with other brain diseases, and therapeutic perspectives. Biol Psychiatry. 2021;90(4):214–25.

Article  Google Scholar 

Zeng D, He S, Ma C, Wen Y, Song W, Xu Q, et al. Network-based approach to identify molecular signatures in the brains of depressed suicides. Psychiatry Res. 2020;294: 113513.

CAS  Article  Google Scholar 

Le Foll B, French L. Transcriptomic characterization of the human habenula highlights drug metabolism and the neuroimmune system. Front Neurosci. 2018;12:742.

Article  Google Scholar