Stevia aquatic extract protects the pancreas from streptozocin (STZ) induced damage: A stereological study
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Title: Stevia aquatic extract protects the pancreas from streptozocin (STZ) induced damage: A stereological studyAuthors:
Dastghaib, SanazKoohpeyma, FarhadKhazayel, SaeedGholizadeh, FatemehPour, Soheila MansoorMokaram, PoonehNoorafshan, AliKeywords: Blood glucose;Candyleaf;Diabetes mellitus;Oxidative stressIssue Date: May-2022Publisher: NIScPR-CSIR, IndiaAbstract: In recent years, among antidiabetic medicinal herbs, Stevia received a lot of attention due to its diverse therapeutic
applications. Despite extensive reports on the effects of Stevia on the pancreas, its molecular mechanism is not clear yet. In
this study, we investigated the protective and preventive effects of oral extracts of Stevia on the pancreas through the
stereological methods in streptozocin (STZ) induced diabetic rats. Thus, 66 adult male rats were assigned to six groups
(n = 11) viz., healthy control, healthy Stevia (400 mg /kg), diabetic-control, diabetic-metformin (500 mg/kg), diabetic-Stevia
and pre-Stevia-diabetic group. Treatment with Stevia significantly reduced fasting blood sugar (FBS) and MDA compared to
the diabetic control group (P Page(s): 299-307URI:
http://nopr.niscair.res.in/handle/123456789/59642ISSN: 0975-1009 (Online); 0019-5189 (Print)Appears in Collections:
IJEB Vol.60(05) [May 2022]Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.
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