Stevia aquatic extract protects the pancreas from streptozocin (STZ) induced damage: A stereological study

Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/59642

Title: Stevia aquatic extract protects the pancreas from streptozocin (STZ) induced damage: A stereological studyAuthors: Dastghaib, Sanaz
Koohpeyma, Farhad
Khazayel, Saeed
Gholizadeh, Fatemeh
Pour, Soheila Mansoor
Mokaram, Pooneh
Noorafshan, AliKeywords: Blood glucose;Candyleaf;Diabetes mellitus;Oxidative stressIssue Date: May-2022Publisher: NIScPR-CSIR, IndiaAbstract: In recent years, among antidiabetic medicinal herbs, Stevia received a lot of attention due to its diverse therapeutic applications. Despite extensive reports on the effects of Stevia on the pancreas, its molecular mechanism is not clear yet. In this study, we investigated the protective and preventive effects of oral extracts of Stevia on the pancreas through the stereological methods in streptozocin (STZ) induced diabetic rats. Thus, 66 adult male rats were assigned to six groups (n = 11) viz., healthy control, healthy Stevia (400 mg /kg), diabetic-control, diabetic-metformin (500 mg/kg), diabetic-Stevia and pre-Stevia-diabetic group. Treatment with Stevia significantly reduced fasting blood sugar (FBS) and MDA compared to the diabetic control group (P Page(s): 299-307URI: http://nopr.niscair.res.in/handle/123456789/59642ISSN: 0975-1009 (Online); 0019-5189 (Print)Appears in Collections:IJEB Vol.60(05) [May 2022]

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