Incidence of Thirty-day MACE among patients presenting to emergency department with low-risk chest pain in a tertiary care hospital.

Abstract

Background: Current guidelines for low-risk chest pain patients recommend obtaining serial ECGs and serial measurements of cardiac troponin between 6 and 12 hours. As a result, the majority of patients require prolonged assessment before safe discharge. There is a need to identify these patients promptly to help in reducing the time to provide the treatment as well as reduce the burden over the ED. Present study was done with the objective of estimating the incidence of thirty-day Major Averse Cardiac Event (MACE) in patients presenting to emergency department with low-risk chest pain, and to compare the Thrombolysis In Myocardial Infarction (TIMI), HEART and Emergency Department Assessment of Chest Pain Score (EDACS) Score in patients with low-risk chest pain. Methods: Present study was descriptive follow up study done at a tertiary care hospital (Fortis Memorial Research Institute, in Gurugram, Haryana, India. Study was conducted from Jan 2018 to Jan 2019. All the patient reporting with low-risk chest pain during study period were recruited in the study. Semi-structured interview schedule was used for the data collection. Outcome variable was MACE (Major adverse cardiac event) event in 30 days. Results: Total 156 participants were included in the study. Mean age of participants was 44.1 years. Out of 156 participants, 10 (6.4%) reported MACE in 30 days of presentation. We found that HEART and EDACS score had incidence of MACE less than 2% in their low-risk groups and TIMI score had incidence of MACE >2% in its low-risk group. Conclusion: EDACS and HEART score can be used in the Emergency department to identify the low-risk chest pain patients. This could help in early identification and save time and other resources.

Competing Interest Statement

The authors have declared no competing interest.

Funding Statement

None

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

Hospitals Ethics Committee (FMRI, Gurugram) (IEC code no.: 2018-007TH-22)

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Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

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I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.

Yes

Data Availability

Data will be made available by the corresponding author on reasonable request.

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