Pediatric Intestinal Transplantation

Elsevier

Available online 20 May 2022, 151181

Seminars in Pediatric SurgeryAbstract

Advancements in donor management, organ preservation and operative techniques, as well as immunosuppressive therapies, have provided children with intestinal failure and its complications a chance not only for enteral autonomy but also long-term survival through intestinal transplantation (ITx). First described in the 1960’s, experience has grown in managing these complex patients both pre- and post-transplant. The goals of this review are to provide a brief history of intestinal transplantation and intestinal rehabilitation in pediatric patients, followed by focused discussions of the indications for ITx, induction and maintenance immunosuppression therapies, common post-operative complications, and outcomes/quality of life post-transplant.

Keywords

Intestinal transplant

intestinal failure

immunosuppression

post-transplant outcomes

infection

post-transplant lymphoproliferative disease

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© 2022 Published by Elsevier Inc.

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