The Scream: Benign Thyroid Tissue as a Lateral Neck Mass : AJSP: Reviews & Reports

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Case Reviews

Wiles, Austin MD; Sayeed, Sadia MD

Author Information

From the Virginia Commonwealth University, Richmond, VA.

Reprints: Austin Blackburn Wiles, MD, Virginia Commonwealth University, Box 980662, 1101 E. Marshall St, Richmond, VA 23298-0662. E-mail: [email protected]; [email protected].

The authors have no funding or conflicts to declare.

doi: 10.1097/PCR.0000000000000500

Metrics Abstract

Variant anatomy and cytomorphological overlap between benign and malignant conditions can coincide to produce diagnostic error. We report the case of an unusually shaped thyroid gland bearing a follicular adenoma interpreted as a metastatic papillary thyroid carcinoma. The shape of the gland had a striking resemblance to The Scream, a painting by Edvard Munch, and directly contributed to the misdiagnosis. We discuss the known embryological mechanisms of thyroid development, ultrasound radiological characteristics of thyroid examination, and the cytomorphologic interpretation of thyroid tissue. The constellation of these elements and the resultant error is eloquently illustrated by Munch’s artistic inspiration.

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