Bussolino F, Mantovani A, Persico G (1997) Molecular mechanisms of blood vessel formation. Trends Biochem Sci 22:251–256
CAS PubMed Article Google Scholar
Korn C, Augustin HG (2015) Mechanisms of vessel pruning and regression. Dev Cell 34:5–17
CAS PubMed Article Google Scholar
Avraamides CJ, Garmy-Susini B, Varner JA (2008) Integrins in angiogenesis and lymphangiogenesis. Nat Rev Cancer 8:604–617
CAS PubMed PubMed Central Article Google Scholar
Weis SM, Cheresh DA (2011) Tumor angiogenesis: molecular pathways and therapeutic targets. Nat Med 17:1359–1370
CAS PubMed Article Google Scholar
Mana G, Valdembri D, Serini G (2020) Conformationally active integrin endocytosis and traffic: why, where, when and how? Biochem Soc Trans 48:83–93
CAS PubMed PubMed Central Article Google Scholar
Moreno-Layseca P, Icha J, Hamidi H, Ivaska J (2019) Integrin trafficking in cells and tissues. Nat Cell Biol 21:122–132
CAS PubMed PubMed Central Article Google Scholar
Parton RG (2018) Caveolae: structure, function, and relationship to disease. Annu Rev Cell Dev Biol 34:111–136
CAS PubMed Article Google Scholar
Hayer A, Stoeber M, Bissig C, Helenius A (2010) Biogenesis of caveolae: stepwise assembly of large caveolin and cavin complexes. Traffic 11:361–382
CAS PubMed Article Google Scholar
Tagawa A, Mezzacasa A, Hayer A, Longatti A, Pelkmans L, Helenius A (2005) Assembly and trafficking of caveolar domains in the cell: caveolae as stable, cargo-triggered, vesicular transporters. J Cell Biol 170:769–779
CAS PubMed PubMed Central Article Google Scholar
Rothberg KG, Heuser JE, Donzell WC, Ying YS, Glenney JR, Anderson RG (1992) Caveolin, a protein component of caveolae membrane coats. Cell 68:673–682
CAS PubMed Article Google Scholar
Shi F, Sottile J (2008) Caveolin-1-dependent beta1 integrin endocytosis is a critical regulator of fibronectin turnover. J Cell Sci 121:2360–2371
CAS PubMed Article Google Scholar
Filippini A, Sica G, D’Alessio A (2018) The caveolar membrane system in endothelium: From cell signaling to vascular pathology. J Cell Biochem 119:5060–5071
CAS PubMed Article Google Scholar
Sowa G (2012) Caveolae, caveolins, cavins, and endothelial cell function: new insights. Front Physiol 2:120
PubMed PubMed Central Article CAS Google Scholar
Norman LL, Oetama RJ, Dembo M, Byfield F, Hammer DA, Levitan I, Aranda-Espinoza H (2010) Modification of cellular cholesterol content affects traction force, adhesion and cell spreading. Cell Mol Bioeng 3:151–162
CAS PubMed Article Google Scholar
Ao M, Wu L, Zhou X, Chen Y (2016) Methyl-β-cyclodextrin impairs the monocyte-adhering ability of endothelial cells by down-regulating adhesion molecules and caveolae and reorganizing the actin cytoskeleton. Biol Pharm Bull 39:1029–1034
CAS PubMed Article Google Scholar
Haq R, Fisher DE (2011) Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer. J Clin Oncol 29:3474–3482
CAS PubMed Article Google Scholar
Medina DL, Fraldi A, Bouche V, Annunziata F, Mansueto G, Spampanato C, Puri C, Pignata A, Martina JA, Sardiello M, Palmieri M, Polishchuk R, Puertollano R, Ballabio A (2011) Transcriptional activation of lysosomal exocytosis promotes cellular clearance. Dev Cell 21:421–430
CAS PubMed PubMed Central Article Google Scholar
Napolitano G, Ballabio A (2016) TFEB at a glance. J Cell Sci 129:2475–2481
CAS PubMed PubMed Central Google Scholar
Palmieri M, Impey S, Kang H, di Ronza A, Pelz C, Sardiello M, Ballabio A (2011) Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways. Hum Mol Genet 20:3852–3866
CAS PubMed Article Google Scholar
Sardiello M, Palmieri M, di Ronza A, Medina DL, Valenza M, Gennarino VA, Di Malta C, Donaudy F, Embrione V, Polishchuk RS, Banfi S, Parenti G, Cattaneo E, Ballabio A (2009) A gene network regulating lysosomal biogenesis and function. Science 325:473–477
CAS PubMed Article Google Scholar
Astanina E, Bussolino F, Doronzo G (2020) Multifaceted activities of transcription factor eb in cancer onset and progression. Mol Oncol 15:327–346
PubMed PubMed Central Article CAS Google Scholar
Corà D, Bussolino F, Doronzo G (2021) TFEB signalling-related MicroRNAs and autophagy. Biomolecules 11:985
PubMed PubMed Central Article CAS Google Scholar
Nnah IC, Wang B, Saqcena C, Weber GF, Bonder EM, Bagley D, De Cegli R, Napolitano G, Medina DL, Ballabio A, Dobrowolski R (2019) TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy. Autophagy 15:151–164
CAS PubMed Article Google Scholar
Raben N, Puertollano R (2016) TFEB and TFE3: linking lysosomes to cellular adaptation to stress. Annu Rev Cell Dev Biol 32:255–278
CAS PubMed PubMed Central Article Google Scholar
Doronzo G, Astanina E, Corà D, Chiabotto G, Comunanza V, Noghero A, Neri F, Puliafito A, Primo L, Spampanato C, Settembre C, Ballabio A, Camussi G, Oliviero S, Bussolino F (2019) TFEB controls vascular development by regulating the proliferation of endothelial cells. EMBO J 38:e98250
PubMed Article CAS Google Scholar
Lu H, Fan Y, Qiao C, Liang W, Hu W, Zhu T, Zhang J, Chen YE (2017) TFEB inhibits endothelial cell inflammation and reduces atherosclerosis. Sci Signal 10:eaah4214
PubMed Article CAS Google Scholar
Fan Y, Lu H, Liang W, Garcia-Barrio MT, Guo Y, Zhang J, Zhu T, Hao Y, Chen YE (2018) Endothelial TFEB (transcription factor EB) positively regulates postischemic angiogenesis. Circ Res 122:945–957
CAS PubMed PubMed Central Article Google Scholar
Emanuel R, Sergin I, Bhattacharya S, Turner J, Epelman S, Settembre C, Diwan A, Ballabio A, Razani B (2014) Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae. Arterioscler Thromb Vasc Biol 34:1942–1952
CAS PubMed PubMed Central Article Google Scholar
Steingrímsson E, Tessarollo L, Reid SW, Jenkins NA, Copeland NG (1998) The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. Development 125:4607–4616
Cho CH, Lee CS, Chang M, Jang IH, Kim SJ, Hwang I, Ryu SH, Lee CO, Koh GY (2004) Localization of VEGFR-2 and PLD2 in endothelial caveolae is involved in VEGF-induced phosphorylation of MEK and ERK. Am J Physiol Heart Circ Physiol 286:H1881-1888
CAS PubMed Article Google Scholar
Labrecque L, Royal I, Surprenant DS, Patterson C, Gingras D, Béliveau R (2003) Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol. Mol Biol Cell 14:334–347
CAS PubMed PubMed Central Article Google Scholar
Mettouchi A (2012) The role of extracellular matrix in vascular branching morphogenesis. Cell Adh Migr 6:528–534
PubMed PubMed Central Article Google Scholar
Shapiro SD (1998) Matrix metalloproteinase degradation of extracellular matrix: biological consequences. Curr Opin Cell Biol 10:602–608
CAS PubMed Article Google Scholar
Schwarzbauer JE, DeSimone DW (2011) Fibronectins, their fibrillogenesis, and in vivo functions. Cold Spring Harb Perspect Biol 3:a005041
PubMed PubMed Central Article CAS Google Scholar
Clapero F, Tortarolo D, Valdembri D, Serini G (2021) Quantifying polarized extracellular matrix secretion in cultured endothelial cells. Methods Mol Biol 2217:301–311
CAS PubMed Article Google Scholar
Mana G, Clapero F, Panieri E, Panero V, Böttcher RT, Tseng HY, Saltarin F, Astanina E, Wolanska KI, Morgan MR, Humphries MJ, Santoro MM, Serini G, Valdembri D (2016) PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nat Commun 7:13546
CAS PubMed PubMed Central Article Google Scholar
Valdembri D, Caswell PT, Anderson KI, Schwarz JP, Konig I, Astanina E, Caccavari F, Norman JC, Humphries MJ, Bussolino F, Serini G (2009) Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biol 7:e25
留言 (0)