1Department of Medicine, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY;

2Basic, Preventive and Clinical Sciences Department, Transilvania University, Brasov, Romania; and

3Department of Cardiology, Colentina Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

*Address for correspondience: Liliana M.Rogozea, MD, PhD, Basic, Preventive and Clinical Sciences Department, Transilvania University, Eroilor 29 Boulevard, Brasov, Romania 500019. E-mail: [email protected]

P. Manu has contributed a chapter to each of the last 4 editions of Cecil Medicine (2008, 2012, 2016, and 2020). L.M. Rogozea and A. Ivanescu-Lint have nothing to disclose. G.A. Dan has received honoraria for lectures sponsored by Bayer, Boehringer Ingelheim, and Pfizer.