Cancer
Melanoma
Targeted therapy
Kinase inhibitors
Immune checkpoint inhibitors
Combination therapy
AbbreviationsADCsantibody-drug conjugates
AJCCAmerican Joint Committee on Cancer
AKTAkt serine threonine kinase
AMacral lentiginous cutaneous melanoma
BAP1BRCA1 associated protein 1
BETiBromodomain and extra-terminal motif protein inhibitors
CDK4/6icyclin-dependent kinase-4/6 inhibitors
CMcutaneous melanoma of the non-acral skin
CTLA-4cytotoxic T-lymphocyte-associated protein 4
FAKifocal adhesion kinase inhibitors
FDAU.S. Food and Drug Administration
GPCRG-protein-coupled receptor
HD-IL-2high-dose interleukin-2
HDACihistone deacetylase inhibitors
HGFhepatocyte growth factor
ICiimmune checkpoint inhibitors
IGF1insulin-like growth factor 1
LAG-3lymphocyte activation gene 3
MAPKmitogen-activated protein kinase
MHCmajor histocompatibility complex
mTORmammalian target of rapamycin
PD-1programmed death protein 1
PD-L1programmed death ligand-1
PFSprogression-free survival
PI3Kphosphoinositide 3-kinase
PROTACsproteolysis-targeting chimeras
RTKsreceptor tyrosine kinases
scRNA-seqsingle-cell RNA-sequencing
TILstumor-infiltrating lymphocytes
TIMEtumor immune microenvironment
T-VECtalimogene laherparepvec
留言 (0)