Anxiety is associated with higher levels of global DNA methylation and altered expression of epigenetic and interleukin-6 genes

aMedical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK

bDepartment of Psychiatry, San Francisco & San Francisco VA Medical Center, University of California, USA

cDepartment of Psychiatry and Mental Health Research, Education and Research Centre, St. Vincent’s University Hospital

dThe UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, UCD School of Medicine and Medical Science, Dublin

eSchool of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's website (www.psychgenetics.com).

Correspondence to Therese M. Murphy, PhD, Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK Tel: +44 139 272 6429; e-mail: [email protected]

Received October 21, 2013

Received in revised form May 30, 2014

Accepted September 10, 2014

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