Mitochondrial supplementation of Sus scrofa metaphase II oocytes alters DNA methylation and gene expression profiles of blastocysts

Purcell SH, Moley KH. The impact of obesity on egg quality. J Assist Reprod Genet. 2011;28(6):517–24.

Article  PubMed  PubMed Central  Google Scholar 

Sharpe RM, Franks S. Environment, lifestyle and infertility—an inter-generational issue. Nat Cell Biol. 2002;4(Suppl):s33-40.

Article  PubMed  Google Scholar 

Navot D, Bergh PA, Williams MA, Garrisi GJ, Guzman I, Sandler B, Grunfeld L. Poor oocyte quality rather than implantation failure as a cause of age-related decline in female fertility. Lancet. 1991;337(8754):1375–7.

CAS  Article  PubMed  Google Scholar 

de Boer KA, Jansen RPS, Leigh DA, Mortimer D. O-165 quantification of mtDNA copy number in the human secondary oocyte. Hum Reprod. 1999;14(9):2419.

Google Scholar 

Iwata H, Goto H, Tanaka H, Sakaguchi Y, Kimura K, Kuwayama T, Monji Y. Effect of maternal age on mitochondrial DNA copy number, ATP content and IVF outcome of bovine oocytes. Reprod Fertil Dev. 2011;23(3):424–32.

CAS  Article  PubMed  Google Scholar 

Kushnir VA, Ludaway T, Russ RB, Fields EJ, Koczor C, Lewis W. Reproductive aging is associated with decreased mitochondrial abundance and altered structure in murine oocytes. J Assist Reprod Genet. 2012;29(7):637–42.

Article  PubMed  PubMed Central  Google Scholar 

May-Panloup P, Chretien MF, Jacques C, Vasseur C, Malthiery Y, Reynier P. Low oocyte mitochondrial DNA content in ovarian insufficiency. Hum Reprod. 2005;20(3):593–7.

CAS  Article  PubMed  Google Scholar 

Reynier P, May-Panloup P, Chretien MF, Morgan CJ, Jean M, Savagner F, Barriere P, Malthiery Y. Mitochondrial DNA content affects the fertilizability of human oocytes. Mol Hum Reprod. 2001;7(5):425–9.

CAS  Article  PubMed  Google Scholar 

Santos TA, El Shourbagy S, St John JC. Mitochondrial content reflects oocyte variability and fertilization outcome. Fertil Steril. 2006;85(3):584–91.

CAS  Article  PubMed  Google Scholar 

Floros VI, Pyle A, Dietmann S, Wei W, Tang WCW, Irie N, Payne B, Capalbo A, Noli L, Coxhead J, et al. Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos. Nat Cell Biol. 2018;20(2):144–51.

CAS  Article  PubMed  PubMed Central  Google Scholar 

John JC. Mitochondria and female germline stem cells—a mitochondrial DNA perspective. Cells. 2019;8(8):852. https://doi.org/10.3390/cells8080852.

CAS  Article  Google Scholar 

Hance N, Ekstrand MI, Trifunovic A. Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis. Hum Mol Genet. 2005;14(13):1775–83.

CAS  Article  PubMed  Google Scholar 

Larsson NG, Wang J, Wilhelmsson H, Oldfors A, Rustin P, Lewandoski M, Barsh GS, Clayton DA. Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat Genet. 1998;18(3):231–6.

CAS  Article  PubMed  Google Scholar 

Spikings EC, Alderson J, St John JC. Regulated mitochondrial DNA replication during oocyte maturation is essential for successful porcine embryonic development. Biol Reprod. 2007;76(2):327–35.

CAS  Article  PubMed  Google Scholar 

Stigliani S, Persico L, Lagazio C, Anserini P, Venturini PL, Scaruffi P. Mitochondrial DNA in Day 3 embryo culture medium is a novel, non-invasive biomarker of blastocyst potential and implantation outcome. Mol Hum Reprod. 2014;20(12):1238–46.

CAS  Article  PubMed  Google Scholar 

Cagnone GL, Tsai TS, Makanji Y, Matthews P, Gould J, Bonkowski MS, Elgass KD, Wong AS, Wu LE, McKenzie M, et al. Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency. Sci Rep. 2016;6:23229.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Kelly RD, Mahmud A, McKenzie M, Trounce IA, St John JC. Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A. Nucleic Acids Res. 2012;40(20):10124–38.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Lee W, Johnson J, Gough DJ, Donoghue J, Cagnone GL, Vaghjiani V, Brown KA, Johns TG, St John JC. Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny. Cell Death Dis. 2015;6: e1664.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Tsai TS, Tyagi S, St John JC. The molecular characterisation of mitochondrial DNA deficient oocytes using a pig model. Hum Reprod. 2018;33(5):942–53.

CAS  Article  PubMed  Google Scholar 

St John JC, Makanji Y, Johnson JL, Tsai TS, Lagondar S, Rodda F, Sun X, Pangestu M, Chen P, Temple-Smith P. The transgenerational effects of oocyte mitochondrial supplementation. Sci Rep. 2019;9(1):6694.

Article  CAS  PubMed  PubMed Central  Google Scholar 

St John JC. Genomic balance: two genomes establishing synchrony to modulate cellular fate and function. Cells. 2019;8(11):1306. https://doi.org/10.3390/cells8111306.

CAS  Article  PubMed Central  Google Scholar 

Larsen MO, Rolin B. Use of the Gottingen minipig as a model of diabetes, with special focus on type 1 diabetes research. ILAR J. 2004;45(3):303–13.

CAS  Article  PubMed  Google Scholar 

Bode G, Clausing P, Gervais F, Loegsted J, Luft J, Nogues V, Sims J. Steering Group of the RP: the utility of the minipig as an animal model in regulatory toxicology. J Pharmacol Toxicol Methods. 2010;62(3):196–220.

CAS  Article  PubMed  Google Scholar 

Kobayashi T, Zhang H, Tang WWC, Irie N, Withey S, Klisch D, Sybirna A, Dietmann S, Contreras DA, Webb R, et al. Principles of early human development and germ cell program from conserved model systems. Nature. 2017;546(7658):416–20.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Zhu Q, Sang F, Withey S, Tang W, Dietmann S, Klisch D, Ramos-Ibeas P, Zhang H, Requena CE, Hajkova P, et al. Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage. Cell Rep. 2021;34(6): 108735.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Krueger F, Andrews SR. Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications. Bioinformatics. 2011;27(11):1571–2.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Exercises: visualising and exploring BS-Seq https://www.bioinformatics.babraham.ac.uk/training/Methylation_Course/Visualising%20and%20exploring%20Exercises.pdf. Accessed 4 Nov 2021.

Ivanova E, Canovas S, Garcia-Martinez S, Romar R, Lopes JS, Rizos D, Sanchez-Calabuig MJ, Krueger F, Andrews S, Perez-Sanz F, et al. DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes. Clin Epigenet. 2020;12(1):64.

CAS  Article  Google Scholar 

Messerschmidt DM, Knowles BB, Solter D. DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos. Genes Dev. 2014;28(8):812–28.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Seisenberger S, Peat JR, Hore TA, Santos F, Dean W, Reik W. Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers. Philos Trans R Soc Lond B Biol Sci. 2013;368(1609):20110330.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, Tonti-Filippini J, Nery JR, Lee L, Ye Z, Ngo QM, et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature. 2009;462(7271):315–22.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Zilberman D, Gehring M, Tran RK, Ballinger T, Henikoff S. Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription. Nat Genet. 2007;39(1):61–9.

CAS  Article  PubMed  Google Scholar 

Liu Y, Han Y, Zhou L, Pan X, Sun X, Liu Y, Liang M, Qin J, Lu Y, Liu P. A comprehensive evaluation of computational tools to identify differential methylation regions using RRBS data. Genomics. 2020;112(6):4567–76.

CAS  Article  PubMed  Google Scholar 

Wu H, Xu T, Feng H, Chen L, Li B, Yao B, Qin Z, Jin P, Conneely KN. Detection of differentially methylated regions from whole-genome bisulfite sequencing data without replicates. Nucleic Acids Res. 2015;43(21): e141.

PubMed  PubMed Central  Google Scholar 

Akalin A, Kormaksson M, Li S, Garrett-Bakelman FE, Figueroa ME, Melnick A, Mason CE. methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles. Genome Biol. 2012;13(10):R87.

Article  PubMed  PubMed Central  Google Scholar 

SeqnMok. https://www.bioinformatics.babraham.ac.uk/projects/seqmonk/. Accessed 4 Nov 2021.

Barlow DP, Bartolomei MS. Genomic imprinting in mammals. Cold Spring Harb Perspect Biol. 2014. https://doi.org/10.1101/cshperspect.a018382.

Article  PubMed  PubMed Central  Google Scholar 

Reik W, Walter J. Genomic imprinting: parental influence on the genome. Nat Rev Genet. 2001;2(1):21–32.

CAS  Article  PubMed  Google Scholar 

Geneimprint: imprinted gene databases. https://www.geneimprint.com/site/genes-by-species.Sus+scrofa. Accessed 4 Nov 2021.

Delaval K, Feil R. Epigenetic regulation of mammalian genomic imprinting. Curr Opin Genet Dev. 2004;14(2):188–95.

CAS  Article  PubMed 

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