Trabecular Bone Score in Rheumatic Disease

Consensus development conference. diagnosis, prophylaxis, and treatment of osteoporosis. Am J Med. 1993;94(6):646–50.

Article  Google Scholar 

Kanis JA, Melton LJ 3rd, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res. 1994;9(8):1137–41. https://doi.org/10.1002/jbmr.5650090802.

CAS  Article  PubMed  Google Scholar 

Compston JE, McClung MR, Leslie WD. Osteoporosis. The Lancet. 2019;393(10169):364–76. https://doi.org/10.1016/s0140-6736(18)32112-3.

CAS  Article  Google Scholar 

Silva BC, Leslie WD. Trabecular bone score. In: Bilezikian JP, editor. Primer on the metabolic bone diseases and disorders of mineral metabolism. 9th ed. Hoboken, NJ: John Wiley & Sons, Inc.; 2019. p. 277–86.

Google Scholar 

McCloskey EV, Oden A, Harvey NC, Leslie WD, Hans D, Johansson H, et al. A meta-analysis of trabecular bone score in fracture risk prediction and its relationship to FRAX. J Bone Miner Res. 2016;31(5):940–8. https://doi.org/10.1002/jbmr.2734.

Article  PubMed  PubMed Central  Google Scholar 

Hans D, Goertzen AL, Krieg MA, Leslie WD. Bone microarchitecture assessed by TBS predicts osteoporotic fractures independent of bone density: the Manitoba study. J Bone Miner Res. 2011;26(11):2762–9. https://doi.org/10.1002/jbmr.499.

Article  PubMed  Google Scholar 

McCloskey EV, Oden A, Harvey NC, Leslie WD, Hans D, Johansson H, et al. Adjusting fracture probability by trabecular bone score. Calcif Tissue Int. 2015;96(6):500–9. https://doi.org/10.1007/s00223-015-9980-x.

CAS  Article  PubMed  Google Scholar 

Martineau P, Leslie WD, Johansson H, Oden A, McCloskey EV, Hans D, et al. Clinical utility of using lumbar spine trabecular bone score to adjust fracture probability: the Manitoba BMD cohort. J Bone Miner Res. 2017;32(7):1568–74. https://doi.org/10.1002/jbmr.3124.

Article  PubMed  Google Scholar 

Kolta S, Briot K, Fechtenbaum J, Paternotte S, Armbrecht G, Felsenberg D, et al. TBS result is not affected by lumbar spine osteoarthritis. Osteoporos Int. 2014;25(6):1759–64. https://doi.org/10.1007/s00198-014-2685-6.

CAS  Article  PubMed  Google Scholar 

Mazzetti G, Berger C, Leslie WD, Hans D, Langsetmo L, Hanley DA, et al. Densitometer-specific differences in the correlation between body mass index and lumbar spine trabecular bone score. J Clin Densitom. 2017;20(2):233–8. https://doi.org/10.1016/j.jocd.2016.11.003.

Article  PubMed  Google Scholar 

Silva BC, Broy SB, Boutroy S, Schousboe JT, Shepherd JA, Leslie WD. Fracture risk prediction by non-BMD DXA measures: the 2015 ISCD Official Positions Part 2: trabecular bone score. J Clin Densitom. 2015;18(3):309–30. https://doi.org/10.1016/j.jocd.2015.06.008.

Article  PubMed  Google Scholar 

Leslie WD, Majumdar SR, Morin SN, Hans D, Lix LM. Change in trabecular bone score (TBS) with antiresorptive therapy does not predict fracture in women: the Manitoba BMD cohort. J Bone Miner Res. 2017;32(3):618–23. https://doi.org/10.1002/jbmr.3054.

CAS  Article  PubMed  Google Scholar 

Krohn K, Schwartz EN, Chung YS, Lewiecki EM. Dual-energy X-ray absorptiometry monitoring with trabecular bone score: 2019 ISCD Official Position. J Clin Densitom. 2019;22(4):501–5. https://doi.org/10.1016/j.jocd.2019.07.006.

Article  PubMed  Google Scholar 

Xue Y, Baker AL, Nader S, Orlander P, Sanchez AJ, Kellam J, et al. Lumbar spine trabecular bone score (TBS) reflects diminished bone quality in patients with diabetes mellitus and oral glucocorticoid therapy. J Clin Densitom. 2018;21(2):185–92. https://doi.org/10.1016/j.jocd.2017.09.003.

Article  PubMed  Google Scholar 

Chuang MH, Chuang TL, Koo M, Wang YF. Trabecular bone score reflects trabecular microarchitecture deterioration and fragility fracture in female adult patients receiving glucocorticoid therapy: a pre-post controlled study. Biomed Res Int. 2017;2017:4210217. https://doi.org/10.1155/2017/4210217.

Article  PubMed  PubMed Central  Google Scholar 

Martineau P, Leslie WD, Johansson H, Harvey NC, McCloskey EV, Hans D, et al. In which patients does lumbar spine trabecular bone score (TBS) have the largest effect? Bone. 2018;113:161–8. https://doi.org/10.1016/j.bone.2018.05.026. Martineau et al. identify glucocorticoid exposure as an independent risk factor for low TBS and show that patients treated with glucocorticoids may benefit more from reclassification using TBS.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Redondo L, Puigoriol E, Rodríguez JR, Peris P, Kanterewicz E. Usefulness of the trabecular bone score for assessing the risk of osteoporotic fracture. Rev Clin Esp (Barc). 2018;218(3):121–7. https://doi.org/10.1016/j.rce.2017.12.005.

CAS  Article  Google Scholar 

Florez H, Hernández-Rodríguez J, Muxi A, Carrasco JL, Prieto-González S, Cid MC, et al. Trabecular bone score improves fracture risk assessment in glucocorticoid-induced osteoporosis. Rheumatology (Oxford). 2020;59(7):1574–80. https://doi.org/10.1093/rheumatology/kez464. Florez et al. describe the association between TBS and fracture (vertebral and fragility) in a cross-sectional study of patients with autoimmune disease who have received glucocorticoids. TBS as a strong predictor of vertebral fracture and fragility fracture, with better discriminative abilities than BMD in a population with autoimmune disease is of particular importance. The high specificity of low TBS combined with low BMD for fracture is of clinical importance, and warrants further study.

CAS  Article  Google Scholar 

Leslie WD, Krieg MA, Hans D. Clinical factors associated with trabecular bone score. J Clin Densitom. 2013;16(3):374–9. https://doi.org/10.1016/j.jocd.2013.01.006.

Article  PubMed  Google Scholar 

Tavassoli S, Rajaei A, Emam MM, Farsad F. Evaluating the value-added of the trabecular bone score in patients with rheumatoid arthritis. Arch Iran Med. 2021;24(3):193–8.

Article  Google Scholar 

Buehring B, Thomas J, Wittkämper T, Baraliakos X, Braun J. Evaluation of the trabecular bone score (TBS) in routine clinical care of patients with inflammatory rheumatic and non-inflammatory diseases: correlation with conventional bone mineral density measurement and prevalence of vertebral fractures. Z Rheumatol. 2020;79(10):1067–74. https://doi.org/10.1007/s00393-020-00764-9.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Ruaro B, Casabella A, Paolino S, Pizzorni C, Ghio M, Seriolo C, et al. Dickkopf-1 (Dkk-1) serum levels in systemic sclerosis and rheumatoid arthritis patients: correlation with the trabecular bone score (TBS). Clin Rheumatol. 2018;37(11):3057–62. https://doi.org/10.1007/s10067-018-4322-9. Ruaro et al. show much lower TBS in RA patients than controls with other musculoskeletal diseases, possibly mediated by glucocorticoid exposure.

Article  PubMed  Google Scholar 

Choi YJ, Chung YS, Suh CH, Jung JY, Kim HA. Trabecular bone score as a supplementary tool for the discrimination of osteoporotic fractures in postmenopausal women with rheumatoid arthritis. Medicine (Baltimore). 2017;96(45):e8661. https://doi.org/10.1097/md.0000000000008661.

Article  Google Scholar 

Killinger Z, Gajdarova L, Kuzma M, Krajcovicova A, Brazdilova K, Jackuliak P, et al. Biologic treatment in comparison to methotrexate has positive effect on trabecular bone score in rheumatoid arthritis patients: 1-year follow-up. Acta Clin Belg. 2019;74(2):121–5. https://doi.org/10.1080/17843286.2018.1512189.

Article  PubMed  Google Scholar 

Ebina K, Hirao M, Hashimoto J, Hagihara K, Kashii M, Kitaguchi K, et al. Assessment of the effects of switching oral bisphosphonates to denosumab or daily teriparatide in patients with rheumatoid arthritis. J Bone Miner Metab. 2018;36(4):478–87. https://doi.org/10.1007/s00774-017-0861-4.

CAS  Article  PubMed  Google Scholar 

Kim D, Cho SK, Kim JY, Choi YY, Sung YK. Association between trabecular bone score and risk factors for fractures in Korean female patients with rheumatoid arthritis. Mod Rheumatol. 2016;26(4):540–5. https://doi.org/10.3109/14397595.2015.1101212.

CAS  Article  PubMed  Google Scholar 

Breban S, Briot K, Kolta S, Paternotte S, Ghazi M, Fechtenbaum J, et al. Identification of rheumatoid arthritis patients with vertebral fractures using bone mineral density and trabecular bone score. J Clin Densitom. 2012;15(3):260–6. https://doi.org/10.1016/j.jocd.2012.01.007.

Article  PubMed  Google Scholar 

Klingberg E, Lorentzon M, Göthlin J, Mellström D, Geijer M, Ohlsson C, et al. Bone microarchitecture in ankylosing spondylitis and the association with bone mineral density, fractures, and syndesmophytes. Arthritis Res Ther. 2013;15(6):R179. https://doi.org/10.1186/ar4368.

Article  PubMed  PubMed Central  Google Scholar 

Wildberger L, Boyadzhieva V, Hans D, Stoilov N, Rashkov R, Aubry-Rozier B. Impact of lumbar syndesmophyte on bone health as assessed by bone density (BMD) and bone texture (TBS) in men with axial spondyloarthritis. Joint Bone Spine. 2017;84(4):463–6. https://doi.org/10.1016/j.jbspin.2016.05.015.

Article  PubMed  Google Scholar 

Boussoualim K, Amouzougan A, Pallot-Prades B, Denarié D, Collet P, Marotte H, et al. Evaluation of bone quality with trabecular bone score in active spondyloarthritis. Joint Bone Spine. 2018;85(6):727–31. https://doi.org/10.1016/j.jbspin.2018.02.006.

Article  PubMed  Google Scholar 

Kang KY, Goo HY, Park SH, Hong YS. Trabecular bone score as an assessment tool to identify the risk of osteoporosis in axial spondyloarthritis: a case-control study. Rheumatology (Oxford). 2018;57(3):462–9. https://doi.org/10.1093/rheumatology/kex377.

CAS  Article  Google Scholar 

Kang KY, Chung MK, Kim HN, Hong YS, Ju JH, Park SH. Severity of sacroiliitis and erythrocyte sedimentation rate are associated with a low trabecular bone score in young male patients with ankylosing spondylitis. J Rheumatol. 2018;45(3):349–56. https://doi.org/10.3899/jrheum.170079.

Article  PubMed  Google Scholar 

Kang KY, Kim IJ, Park SH, Hong YS. Associations between trabecular bone score and vertebral fractures in patients with axial spondyloarthritis. Rheumatology (Oxford). 2018;57(6):1033–40. https://doi.org/10.1093/rheumatology/key027.

Article  Google Scholar 

Caparbo VF, Furlam P, Saad CGS, Alvarenga JC, Aubry-Rozier B, Hans D, et al. Assessing bone impairment in ankylosing spondylitis (AS) using the trabecular bone score (TBS) and high-resolution peripheral quantitative computed tomography (HR-pQCT). Bone. 2019;122:8–13. https://doi.org/10.1016/j.bone.2019.01.024.

Article  PubMed  Google Scholar 

Richards C, Hans D, Leslie WD. Trabecular bone score (TBS) predicts fracture in ankylosing spondylitis: the Manitoba BMD Registry. J Clin Densitom. 2020;23(4):543–8. https://doi.org/10.1016/j.jocd.2020.01.003. Richards et al. show TBS predicts incident fracture independent of FRAX in patients with ankylosing spondylitis in a longitudinal study.

Article  PubMed  Google Scholar 

Jung JY, Han SH, Hong YS, Park SH, Ju JH, Kang KY. Inflammation on spinal magnetic resonance imaging is associated with poor bone quality in patients with ankylosing spondylitis. Mod Rheumatol. 2019;29(5):829–35. https://doi.org/10.1080/14397595.2018.1510877.

Article  PubMed  Google Scholar 

Ivanova MMI, Boyadzhieva V, Stoilov R, Dimitrov N, Stoilov N, et al. Relationship between physical function, disease activity, spinal mobility and bone parameters (trabecular bone score and bone mineral density) in ankylosing spondylitis patients. Biotechnol Biotechnol Equipment. 2015;29:956–62. https://doi.org/10.1080/13102818.2015.1057525.

CAS  Article  Google Scholar 

Kang KY, Ju JH, Park SH, Hong YS. Longitudinal association between trabecular bone loss and disease activity in axial spondyloarthritis: a 4-year prospective study. J Rheumatol. 2020;47(9):1330–7. https://doi.org/10.3899/jrheum.190749. Kang et al. show an association between disease activity in a prospective study of patients with spondyloarthritis.

CAS  Article  PubMed  Google Scholar 

Kang KY, Jung JY, Lee SK, Min HK, Hong YS, Park SH, et al. Trabecular bone score value is associated with new bone formation independently of fat metaplasia on spinal magnetic resonance imaging in patients with ankylosing spondylitis. Scand J Rheumatol. 2020;49(4):292–300. https://doi.org/10.1080/03009742.2019.1704053.

CAS  Article

留言 (0)

沒有登入
gif