Lloyd RV, Osamura RY, Klöppel G, Rosai J, International Agency for Research on Cancer (2017) WHO classification of tumours of endocrine organs, 4th edition. International Agency for Research on Cancer, Lyon
Amin MB, American Joint Committee on Cancer, American Cancer Society (2017) AJCC cancer staging manual, Eight edition / editor-in-chief, Mahul B. Amin, MD, FCAP ; editors, Stephen B. Edge, MD, FACS [and 16 others] ; Donna M. Gress, RHIT, CTR-Technical editor ; Laura R. Meyer, CAPM-Managing editor. American Joint Committee on Cancer, Springer, Chicago IL
Werner TA, Dizdar L, Nolten I, Riemer JC, Mersch S, Schütte SC, Driemel C, Verde PE, Raba K, Topp SA, Schott M, Knoefel WT, Krieg A (2017) Survivin and XIAP - two potential biological targets in follicular thyroid carcinoma. Sci Rep 7:11383. https://doi.org/10.1038/s41598-017-11426-3
CAS Article PubMed PubMed Central Google Scholar
Wu J, Zhang Y, Cheng R, Gong W, Ding T, Zhai Q, Wang Y, Meng B, Sun B (2019) Expression of epithelial-mesenchymal transition regulators TWIST, SLUG and SNAIL in follicular thyroid tumours may relate to widely invasive, poorly differentiated and distant metastasis. Histopathology 74:780–791. https://doi.org/10.1111/his.13778
Nicolson NG, Paulsson JO, Juhlin CC, Carling T, Korah R (2020) Transcription Factor Profiling Identifies Spatially Heterogenous Mediators of Follicular Thyroid Cancer Invasion. Endocr Pathol 31:367–376. https://doi.org/10.1007/s12022-020-09651-0
CAS Article PubMed PubMed Central Google Scholar
Orlandi F, Saggiorato E, Pivano G, Puligheddu B, Termine A, Cappia S, De Giuli P, Angeli A (1998) Galectin-3 is a presurgical marker of human thyroid carcinoma. Cancer Res 58:3015–3020
Xu XC, el-Naggar AK, Lotan R (1995) Differential expression of galectin-1 and galectin-3 in thyroid tumors. Potential diagnostic implications. Am J Pathol 147:815–822
Lloyd RV, Carney JA, Ferreiro JA, Jin L, Thompson GB, Van Heerden JA, Grant CS, Wollan PC (1995) Immunohistochemical Analysis of the Cell Cycle-Associated Antigens Ki-67 and Retinoblastoma Protein in Parathyroid Carcinomas and Adenomas. Endocr Pathol 6:279–287. https://doi.org/10.1007/BF02738728
Juhlin CC, Erickson LA (2021) Genomics and Epigenomics in Parathyroid Neoplasia: from Bench to Surgical Pathology Practice. Endocr Pathol 32:17–34. https://doi.org/10.1007/s12022-020-09656-9
Pennanen M, Heiskanen I, Sane T, Remes S, Mustonen H, Haglund C, Arola J (2015) Helsinki score-a novel model for prediction of metastases in adrenocortical carcinomas. Hum Pathol 46:404–410. https://doi.org/10.1016/j.humpath.2014.11.015
Juhlin CC, Bertherat J, Giordano TJ, Hammer GD, Sasano H, Mete O (2021) What Did We Learn from the Molecular Biology of Adrenal Cortical Neoplasia? From Histopathology to Translational Genomics. Endocr Pathol 32:102–133. https://doi.org/10.1007/s12022-021-09667-0
CAS Article PubMed Google Scholar
Kimura N, Takayanagi R, Takizawa N, Itagaki E, Katabami T, Kakoi N, Rakugi H, Ikeda Y, Tanabe A, Nigawara T, Ito S, Kimura I, Naruse M, Phaeochromocytoma Study Group in Japan (2014) Pathological grading for predicting metastasis in phaeochromocytoma and paraganglioma. Endocr Relat Cancer 21:405–414. https://doi.org/10.1530/ERC-13-0494
Juhlin CC (2021) Challenges in Paragangliomas and Pheochromocytomas: from Histology to Molecular Immunohistochemistry. Endocr Pathol 32:228–244. https://doi.org/10.1007/s12022-021-09675-0
Article PubMed PubMed Central Google Scholar
Kakudo K, Wakasa T, Ohta Y, Yane K, Ito Y, Yamashita H (2015) Prognostic classification of thyroid follicular cell tumors using Ki-67 labeling index: risk stratification of thyroid follicular cell carcinomas. Endocr J 62:1–12. https://doi.org/10.1507/endocrj.EJ14-0293
Ito Y, Hirokawa M, Miyauchi A, Masuoka H, Yabuta T, Fukushima M, Kihara M, Higashiyama T, Kobayashi K, Miya A (2016) Prognostic impact of Ki-67 labeling index in minimally invasive follicular thyroid carcinoma. Endocr J 63:913–917. https://doi.org/10.1507/endocrj.EJ16-0277
CAS Article PubMed Google Scholar
Katoh R, Bray CE, Suzuki K, Komiyama A, Hemmi A, Kawaoi A, Oyama T, Sugai T, Sasou S (1995) Growth activity in hyperplastic and neoplastic human thyroid determined by an immunohistochemical staining procedure using monoclonal antibody MIB-1. Hum Pathol 26:139–146. https://doi.org/10.1016/0046-8177(95)90029-2
CAS Article PubMed Google Scholar
Erickson LA, Jin L, Wollan PC, Thompson GB, van Heerden J, Lloyd RV (1998) Expression of p27kip1 and Ki-67 in benign and malignant thyroid tumors. Mod Pathol 11:169–174
Tallini G, Garcia-Rostan G, Herrero A, Zelterman D, Viale G, Bosari S, Carcangiu ML (1999) Downregulation of p27KIP1 and Ki67/Mib1 labeling index support the classification of thyroid carcinoma into prognostically relevant categories. Am J Surg Pathol 23:678–685. https://doi.org/10.1097/00000478-199906000-00007
CAS Article PubMed Google Scholar
Rickert D, Mittermayer C, Lindenfelser R, Biesterfeld S (2000) MIB-1 immunohistometry of follicular adenoma and follicular carcinoma of the thyroid gland. Anal Quant Cytol Histol 22:229–234
Ludvíková M, Holubec L, Ryska A, Topolcan O (2005) Proliferative markers in diagnosis of thyroid tumors: a comparative study of MIB-1 and topoisomerase II-a immunostaining. Anticancer Res 25:1835–1840
Sofiadis A, Tani E, Foukakis T, Kjellman P, Skoog L, Höög A, Wallin G, Zedenius J, Larsson C (2009) Diagnostic and prognostic potential of MIB-1 proliferation index in thyroid fine needle aspiration biopsy. Int J Oncol 35:369–374
Kjellman P, Wallin G, Höög A, Auer G, Larsson C, Zedenius J (2003) MIB-1 index in thyroid tumors: a predictor of the clinical course in papillary thyroid carcinoma. Thyroid 13:371–380. https://doi.org/10.1089/105072503321669866
Lindfors H, Ihre Lundgren C, Zedenius J, Juhlin CC, Shabo I (2021) The Clinical Significance of Lymph Node Ratio and Ki-67 Expression in Papillary Thyroid Cancer. World J Surg 45:2155–2164. https://doi.org/10.1007/s00268-021-06070-y
Article PubMed PubMed Central Google Scholar
Mu N, Juhlin CC, Tani E, Sofiadis A, Reihnér E, Zedenius J, Larsson C, Nilsson I-L (2018) High Ki-67 index in fine needle aspiration cytology of follicular thyroid tumors is associated with increased risk of carcinoma. Endocrine 61:293–302. https://doi.org/10.1007/s12020-018-1627-z
CAS Article PubMed PubMed Central Google Scholar
Rindi G, Klöppel G, Alhman H, Caplin M, Couvelard A, de Herder WW, Erikssson B, Falchetti A, Falconi M, Komminoth P, Körner M, Lopes JM, McNicol A-M, Nilsson O, Perren A, Scarpa A, Scoazec J-Y, Wiedenmann B, all other Frascati Consensus Conference participants, European Neuroendocrine Tumor Society (ENETS) (2006) TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system. Virchows Arch 449:395–401. https://doi.org/10.1007/s00428-006-0250-1
Hysek M, Paulsson JO, Jatta K, Shabo I, Stenman A, Höög A, Larsson C, Zedenius J, Juhlin CC (2019) Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease. Cancers (Basel) 11. https://doi.org/10.3390/cancers11101443
Juhlin CC (2020) A Clinical Overview of Telomerase-Associated Aberrancies in Follicular Thyroid Tumors as Diagnostic and Prognostic Markers: Tert Alert! Scand J Surg 109:187–192. https://doi.org/10.1177/1457496919850434
CAS Article PubMed Google Scholar
Liu T, Wang N, Cao J, Sofiadis A, Dinets A, Zedenius J, Larsson C, Xu D (2014) The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas. Oncogene 33:4978–4984. https://doi.org/10.1038/onc.2013.446
CAS Article PubMed Google Scholar
Paulsson JO, Mu N, Shabo I, Wang N, Zedenius J, Larsson C, Juhlin CC (2018) TERT aberrancies: a screening tool for malignancy in follicular thyroid tumours. Endocr Relat Cancer 25:723–733. https://doi.org/10.1530/ERC-18-0050
CAS Article PubMed Google Scholar
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, Haugen BR, Hauger BR, Kloos RT, Lee SL, Mandel SJ, Mazzaferri EL, McIver B, Pacini F, Schlumberger M, Sherman SI, Steward DL, Tuttle RM (2009) Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 19:1167–1214. https://doi.org/10.1089/thy.2009.0110
Nicolson NG, Murtha TD, Dong W, Paulsson JO, Choi J, Barbieri AL, Brown TC, Kunstman JW, Larsson C, Prasad ML, Korah R, Lifton RP, Juhlin CC, Carling T (2018) Comprehensive Genetic Analysis of Follicular Thyroid Carcinoma Predicts Prognosis Independent of Histology. J Clin Endocrinol Metab 103:2640–2650. https://doi.org/10.1210/jc.2018-00277
Bournaud C, Descotes F, Decaussin-Petrucci M, Berthiller J, de la Fouchardière C, Giraudet A-L, Bertholon-Gregoire M, Robinson P, Lifante J-C, Lopez J, Borson-Chazot F (2019) TERT promoter mutations identify a high-risk group in metastasis-free advanced thyroid carcinoma. Eur J Cancer 108:41–49. https://doi.org/10.1016/j.ejca.2018.12.003
CAS Article PubMed Google Scholar
Landa I, Ganly I, Chan TA, Mitsutake N, Matsuse M, Ibrahimpasic T, Ghossein RA, Fagin JA (2013) Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease. J Clin Endocrinol Metab 98:E1562-1566. https://doi.org/10.1210/jc.2013-2383
CAS Article PubMed PubMed Central Google Scholar
Tanaka A, Matsuse M, Saenko V, Nakao T, Yamanouchi K, Sakimura C, Yano H, Nishihara E, Hirokawa M, Suzuki K, Miyauchi A, Eguchi S, Yoshiura K-I, Yamashita S, Nagayasu T, Mitsutake N (2019) TERT mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid Carcinomas. Thyroid 29:1105–1114. https://doi.org/10.1089/thy.2018.0695
CAS Article PubMed Google Scholar
Hellgren LS, Olsson A, Kaufeldt A, Paulsson JO, Hysek M, Stenman A, Zedenius J, Larsson C, Höög A, Juhlin CC (2021) Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool? J Clin Pathol jclinpath-2021–207631. https://doi.org/10.1136/jclinpath-2021-207631
Hysek M, Jatta K, Hellgren LS, Stenman A, Larsson C, Zedenius J, Juhlin CC (2021) Spatial Distribution Patterns of Clinically Relevant TERT Promoter Mutations in Follicular Thyroid Tumors of Uncertain Malignant Potential: Advantages of the Digital Droplet PCR Technique. J Mol Diagn 23:212–222. https://doi.org/10.1016/j.jmoldx.2020.10.016
CAS Article PubMed Google Scholar
Nikiforova MN, Wald AI, Roy S, Durso MB, Nikiforov YE (2013) Targeted next-generation sequencing panel (ThyroSeq) for detection of mutations in thyroid cancer. J Clin Endocrinol Metab 98:E1852-1860. https://doi.org/10.1210/jc.2013-2292
CAS Article PubMed PubMed Central Google Scholar
Duick DS, Klopper JP, Diggans JC, Friedman L, Kennedy GC, Lanman RB, McIver B (2012) The impact of benign gene expression classifier test results on the endocrinologist-patient decision to operate on patients with thyroid nodules with indeterminate fine-needle aspiration cytopathology. Thyroid 22:996–1001. https://doi.org/10.1089/thy.2012.0180
CAS Article PubMed PubMed Central Google Scholar
Baloch Z, Mete O, Asa SL (2018) Immunohistochemical Biomarkers in Thyroid Pathology. Endocr Pathol 29:91–112. https://doi.org/10.1007/s12022-018-9532-9
CAS Article PubMed Google Scholar
Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho Simões M, Tallini G, Mete O (2022) Overview of the 2022 WHO Classification of Thyroid Neoplasms. Endocrine Pathology. https://doi.org/10.1007/s12022-022-09707-3
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