Identification of Centromere-Specific Repeats in the Zebra Finch Genome

Cytogenetic and Genome Research

Takki O.a· Komissarov A.b· Kulak M.a· Galkina S.a

Author affiliations

aDepartment of Genetics and Biotechnology, Saint Petersburg State University, Saint Petersburg, Russian Federation
bApplied Genomics Laboratory, SCAMT Institute, ITMO University, Saint Petersburg, Russian Federation

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Article / Publication Details

First-Page Preview

Abstract of Original Article

Received: September 13, 2021
Accepted: December 25, 2021
Published online: March 11, 2022

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: https://www.karger.com/CGR

Abstract

Tandem repetitive sequences represent a significant part of many genomes but remain poorly characterized due to various methodological difficulties. Here, we describe the tandem repeat composition in the genome of zebra finch, Taeniopygia guttata, a species that has long served as an animal model, primarily in neurobiology and comparative genomics. Using available genome sequencing raw read datasets, we bioinformatically reconstructed consensus sequences of several tandem repeats and proved that the most abundant ones, Tgut191A and Tgut716A, are centromere-associated in chromosomes. Each centromeric region can have a different number of copies of each repeat, with Tgut716A enrichment in almost all microchromosomes and sex chromosomes. Sequences similar to Tgut191A and Tgut716A found in other Estrildidae and Viduidae species can be considered as candidate centromeric sequences, but this requires further cytogenetic verification.

© 2022 S. Karger AG, Basel

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First-Page Preview

Abstract of Original Article

Received: September 13, 2021
Accepted: December 25, 2021
Published online: March 11, 2022

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 0

ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)

For additional information: https://www.karger.com/CGR

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