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Formulation and In Vitro-Ex vivo Evaluation of Cannabidiol and Cannabidiol-Valine-Hemisuccinate Loaded Lipid-Based Nanoformulations for Ocular Applications
Formulation and In Vitro-Ex vivo Evaluation of Cannabidiol and Cannabidiol-Valine-Hemisuccinate Loaded Lipid-Based Nanoformulations for Ocular Applications
Cannabis sativa L. is a herbaceous plant containing psychoactive agents popular for its recreational and medicinal uses (K...
An insight in the future of healthcare: integrating digital twin for personalized medicine
An insight in the future of healthcare: integrating digital twin for personalized medicine
An increasingly popular concept in numerous fields is a digital twin, which is a virtual counterpart of an object. This te...
SEEIIST – a new research facility for tumor treatment and biomedical investigations with proton and ion beams
SEEIIST – a new research facility for tumor treatment and biomedical investigations with proton and ion beams
A project for the establishment of an international intergovernmental scientific organization in the region of South East ...
ENSEMBLE PLUS: final results of shorter ocrelizumab infusion from a randomized controlled trial
ENSEMBLE PLUS: final results of shorter ocrelizumab infusion from a randomized controlled trial
Ocrelizumab is an approved intravenously administered anti-CD20 antibody for multiple sclerosis (MS). The safety profile a...
'Armed kyphoplasty with posterior stabilization avoids corpectomy in complex thoracolumbar spine fractures: a case series
'Armed kyphoplasty with posterior stabilization avoids corpectomy in complex thoracolumbar spine fractures: a case series
WHAT IS ALREADY KNOWN ON THIS TOPICComplex thoracolumbar fractures of osteoporotic, traumatic, or neoplastic nature must b...
The digital motor output: a conceptual framework for a meaningful clinical performance metric for a motor neuroprosthesis
The digital motor output: a conceptual framework for a meaningful clinical performance metric for a motor neuroprosthesis
In recent years, the majority of the population has become increasingly reliant on continuous and independent control of s...
Mechanical thrombectomy in patients with acute ischemic stroke in the USA before and after time window expansion
Mechanical thrombectomy in patients with acute ischemic stroke in the USA before and after time window expansion
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Cleara...
Intracranial atherosclerosis update for neurointerventionalists
Intracranial atherosclerosis update for neurointerventionalists
IntroductionThe management of intracranial atherosclerotic disease (ICAD) has been evolving with advanced imaging, refinem...
Management of wide-neck aneurysms in 2024: how does one make the best treatment decision when there are so many good options?
Management of wide-neck aneurysms in 2024: how does one make the best treatment decision when there are so many good options?
A middle-aged patient walks into the office for the first time with an unruptured, medium sized, wide-neck middle cerebral...
Response to stent retriever for tandem acute revascularization technique (START): a novel technique for endovascular management of tandem occlusions
Response to stent retriever for tandem acute revascularization technique (START): a novel technique for endovascular management of tandem occlusions
We read with great interest the videographic depiction of the stent retriever for tandem acute revascularization technique...
Optimal duration of dual antiplatelet therapy for stent-assisted coiling or flow diverter placement
Optimal duration of dual antiplatelet therapy for stent-assisted coiling or flow diverter placement
IntroductionThromboembolic complications are common and cause morbidity after neuroendovascular treatment for cerebral ane...
Predictors of aneurysm occlusion after treatment with flow diverters: a systematic literature review
Predictors of aneurysm occlusion after treatment with flow diverters: a systematic literature review
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Cleara...
Intravascular ultrasound characteristics of different types of stenosis in idiopathic intracranial hypertension with venous sinus stenosis
Intravascular ultrasound characteristics of different types of stenosis in idiopathic intracranial hypertension with venous sinus stenosis
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Cleara...
Rebleeding following aneurysmal subarachnoid hemorrhage before 'endovascular first treatment: a retrospective case-control study of published scoring systems
Rebleeding following aneurysmal subarachnoid hemorrhage before 'endovascular first treatment: a retrospective case-control study of published scoring systems
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Cleara...
Crystallinity regulation induced organics degradation on Ultra-thin 2D Co3O4/SiO2 Nanosheets: the critical trigger of oxygen vacancy
As an antibiotic drug, sulfamethoxazole (SMX) is a nitrogen-containing and sulfur-containing heterocyclic compound, which ...
Correction: Nano-pelargonidin modulates p53/PARP/HSP 90/XRCC1 signaling axis to combat cypermethrin-induced genotoxicity and metabolic dysfunction in fish: a molecular docking predicted in vivo approach
Correction for ‘Nano-pelargonidin modulates p53/PARP/HSP 90/XRCC1 signaling axis to combat cypermethrin-induced genotoxici...
“Visible range curvature fiber-optic sensor with low strain-temperature dependence”
“Visible range curvature fiber-optic sensor with low strain-temperature dependence”
Curvature optical fiber sensors have emerged as a promising alternative to address the challenges in many areas, such as m...
Dual-frequency and multi-linewidth laser based on self-injection locking for optical gyroscopes
Dual-frequency and multi-linewidth laser based on self-injection locking for optical gyroscopes
The all-solid-state, zero mechanical wear, and high reliability of optical gyroscopes have contributed to their increasing...
Prognostic and predictive value of tumor deposits in advanced signet ring cell colorectal cancer: SEER database analysis and multicenter validation
Prognostic and predictive value of tumor deposits in advanced signet ring cell colorectal cancer: SEER database analysis and multicenter validation
Colorectal signet-ring cell carcinoma (SRCC) is a rare cancer with a bleak prognosis. The relationship between its clinico...
Scleroderma
Scleroderma
This fully-updated third edition of Scleroderma builds upon the well-regarded approach in the previous editions.
A 50-gene biomarker identifies estrogen receptor-modulating chemicals in a microarray compendium
A 50-gene biomarker identifies estrogen receptor-modulating chemicals in a microarray compendium
New approach methodologies (NAMs) that efficiently provide information about chemical hazards without using whole animals ...
Therapeutic targeting of thioredoxin reductase 1 causes ferroptosis while potentiating anti-PD-1 efficacy in head and neck cancer
Therapeutic targeting of thioredoxin reductase 1 causes ferroptosis while potentiating anti-PD-1 efficacy in head and neck cancer
Head and neck squamous cell carcinoma (HNSCC) is the most common type of head and neck cancer and causes significant cance...
Biochanin a ameliorates DSS-induced ulcerative colitis by improving colonic barrier function and protects against the development of spontaneous colitis in the Muc2 deficient mice
Biochanin a ameliorates DSS-induced ulcerative colitis by improving colonic barrier function and protects against the development of spontaneous colitis in the Muc2 deficient mice
Ulcerative colitis (UC) is a chronic and relapsing inflammatory bowel disease that characterized mostly by ulcers or open ...
In vitro cleavage of tumor necrosis factor α (TNFα) by Signal-Peptide-Peptidase-like 2b (SPPL2b) resembles mechanistic principles observed in the cellular context
In vitro cleavage of tumor necrosis factor α (TNFα) by Signal-Peptide-Peptidase-like 2b (SPPL2b) resembles mechanistic principles observed in the cellular context
KeywordsIntramembrane aspartyl proteolysisSignal peptide peptidase family (SPP/SPPL)In vitro cleavage assaySPL-707(Z-LL)2-...
Sex Dimorphism in Pain Threshold and Neuroinflammatory Response: The Protective Effect of Female Sexual Hormones on Behavior and Seizures in an Allergic Rhinitis Model
Sex Dimorphism in Pain Threshold and Neuroinflammatory Response: The Protective Effect of Female Sexual Hormones on Behavior and Seizures in an Allergic Rhinitis Model
Our previous research demonstrated that allergic rhinitis could impact behavior and seizure threshold in male mice. Howeve...
A COVID-19 specific multiparametric and ECG-based score for the prediction of in-hospital mortality: ELCOVID score
A COVID-19 specific multiparametric and ECG-based score for the prediction of in-hospital mortality: ELCOVID score
We aimed to develop and validate a COVID-19 specific scoring system, also including some ECG features, to predict all-caus...
Missed diagnosis—a major barrier to patient access to obesity healthcare in the primary care setting
Missed diagnosis—a major barrier to patient access to obesity healthcare in the primary care setting
To investigate whether individuals with an elevated BMI measurement, for whom a diagnosis of overweight or obesity (OW/OB)...
Bi-functional absorption performance of metamaterial structure based on metallic-square with U-shaped slot
Bi-functional absorption performance of metamaterial structure based on metallic-square with U-shaped slot
In this manuscript, a bi-functional absorption performance based on a new and simple design of metamaterial absorber is ac...
Optical coherence tomography angiography for the differentiation of diabetic nephropathy from non-diabetic renal disease
Optical coherence tomography angiography for the differentiation of diabetic nephropathy from non-diabetic renal disease
KeywordsDiabetic nephropathynon-diabetic renal diseasediabetic retinopathyoptical coherence tomography angiographyAbbrevia...
High cure rates of Mycoplasma genitalium following empiric treatment with azithromycin alongside frequent detection of macrolide resistance in Austria
High cure rates of Mycoplasma genitalium following empiric treatment with azithromycin alongside frequent detection of macrolide resistance in Austria
Mycoplasma genitalium (MG) is an emerging sexually transmitted infection, often harboring resistance-associated mutations ...
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