Neurofilament Light Chain Determination: Referee for Future Vitamin D3 Supplementation in Multiple Sclerosis?

Goischke H.-K.

Author affiliations

Internal Medicine, Rehabilitation Medicine, Social Medicine, Bad Brückenau, Germany

Log in to MyKarger to check if you already have access to this content.

Buy FullText & PDF Unlimited re-access via MyKarger Unrestricted printing, no saving restrictions for personal use
read more

CHF 38.00 *
EUR 35.00 *
USD 39.00 *

Select

KAB

Buy a Karger Article Bundle (KAB) and profit from a discount!

If you would like to redeem your KAB credit, please log in.

Save over 20% compared to the individual article price.

Learn more

Rent/Cloud Rent for 48h to view Buy Cloud Access for unlimited viewing via different devices Synchronizing in the ReadCube Cloud Printing and saving restrictions apply Rental: USD 8.50
Cloud: USD 20.00

Select

Subscribe Access to all articles of the subscribed year(s) guaranteed for 5 years Unlimited re-access via Subscriber Login or MyKarger Unrestricted printing, no saving restrictions for personal use read more

Subcription rates

Select

* The final prices may differ from the prices shown due to specifics of VAT rules.

Article / Publication Details

Received: November 21, 2021
Accepted: November 27, 2021
Published online: February 09, 2022

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1021-7401 (Print)
eISSN: 1423-0216 (Online)

For additional information: https://www.karger.com/NIM


First-Page Preview
Abstract of Letter References Yuan X, Guo L, Jiang C, Yang X, Huang J. The effect of different administration time and dosage of vitamin D supplementation in patients with multiple sclerosis: a meta-analysis of randomized controlled trials. Neuroimmunomodulation. 2021;28(3):118–28. Bittner S, Oh J, Havrdova EK, Tintore M, Zipp F. The potential of serum neurofilament as biomarker for multiple sclerosis. Brain. 2021;144(10):2954–63. Shoemaker TJ, Mowry EM. A review of vitamin D supplementation as disease-modifying therapy. Mult Scler. 2018;24(1):6–11. Sintzel MB, Rametta M, Reder AT. Vitamin D and multiple sclerosis: a comprehensive review. Neurol Ther. 2018;7(1):59–85. Ostkamp P, Salmen A, Pignolet B, Görlich D, Andlauer TFM, Schulte-Mecklenbeck A, et al. Sunligth exposure exerts immunomodulatory effects to reduce multiple sclerosis severity. Proc Natl Acad Sci U S A. 2021;118(1):e2018457118. Goischke HK. Multiple sclerosis and vitamin D supplementation- could the “non-daily” intake mode falsify the outcome of vitamin D studies? From pharmacokinetics and pathophysiology to personalized medicine”. EC Neurology RCO. 2019;01:13–7. Hartl C, Obermeier V, Gerdes LA, Brügel M, Kries R, Kümpfel T. Seasonal variations of 25-OH vitamin D serum levels are associated with clinical disease activity in multiple sclerosis patients. J Neurol Sci. 2017;375:160–4. Goischke HK. Vitamin D supplementation as add-on therapy in multiple sclerosis- balance between benefit and risk: a commentary an vitamin D supplementation in central nervous system demyelinating disease – enough is enough. Int J Mol Sci. 2019;20(6):1513. Hupperts R, Smolders J, Vieth R, Holmoy T, Marhardt K, Schluep M, et al. Randomized trial of daily high-dose vitamin D3 in patients with RRMS receiving subcutaneous interferon β-1a. Neurology. 2019;93(20):e1906–16. Sandberg L, Biström M, Salzer J, Vagberg M, Scenningsson A, Sundström P, et al. Vitamin D and axonal injury in multiple sclerosis. Mult Scler. 2016;22(8):1027–31. Cortese M, Munger KL, Martinez-Lapiscina EH, Baro Ch, Edan G, Freedman MS, et al. Vitamin D, smoking, EBV, and long-term cognitive performance in MS. Neurology. 2020;94(18):e1950–e1960. Hänninen K, Jääskeläinen O, Herukka SK, Soilu-Hänninen M. Vitamin D supplementation and serum neurofilament light chain in interferon-beta-1b-treated MS patients. Brain Behav. 2020;10(9):e01772. Hollis BW, Wagner CL. The role of the parent compound vitamin D with respect to metabolism and function: why clinical dose intervals can affect clinical outcomes. J Clin Endocrinol Metab. 2013;98(12):4619–28. Smolders J, Torkildsen Ø, Camu W, Holmøy T. An update on vitamin D and disease activity in multiple sclerosis. CNS Drugs. 2019;33(12):1187–99. Holmoy T, Rosjo E, Zetterberg H, Blennow K, Lindström JC, Steffensen LH, et al. Vitamin D supplementation and neurofilament ligth chain in multiple sclerosis. Acta Neurol Scand. 2019;139(2):172–6. Rosjo E, Lindstrom C, Holmoy T, Myhr KM, Varhaug KN, Torkildsen O. Natural variation of vitamin D and neurofilament light chain in relapsing-remitting multiple sclerosis. Front Neurol. 2020;30(11):329. Feige J, Moser T, Bieler L, Schwenker K, Hauer L, Sellner J. Vitamin D supplementation in multiple sclerosis: a critical analysis of potentials and threats. Nutrients. 2020;12(3):783. Miclea A, Bagnoud M. Chan A, Hoepner R. A brief review of the effects of vitamin D on multiple sclerosis. Front Immunol. 2020;11:781. Lee YA, Yoon S, Kim SY, Youn YC. Association of 25-hydroxyvitamin D status with brain volume changes. Food Sci Nutr. 2021;9(8):4169–4175. Bäcker-Koduah P, Bellmann-Strobl J, Scheel M, Wuerfel J, Wernecke KD, Dörr J, et al. Vitamin D and Disease Severity in Multiple Sclerosis-Baseline Data from the Randomized Controlled Trial (EVIDIMS). Front Neurol. 2020;11:129. Article / Publication Details

Received: November 21, 2021
Accepted: November 27, 2021
Published online: February 09, 2022

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1021-7401 (Print)
eISSN: 1423-0216 (Online)

For additional information: https://www.karger.com/NIM

Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

留言 (0)

沒有登入
gif