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mRNA therapy for a rare childhood disease
mRNA therapy for a rare childhood disease
An mRNA-based drug aims to replace a faulty enzyme and restore metabolic function in children with propionic acidemia — wi...
Nivolumab for mismatch-repair-deficient or hypermutated gynecologic cancers: a phase 2 trial with biomarker analyses
Nivolumab for mismatch-repair-deficient or hypermutated gynecologic cancers: a phase 2 trial with biomarker analyses
Programmed death-1 (PD-1) inhibitors are approved for therapy of gynecologic cancers with DNA mismatch repair deficiency (...
Triglyceride- glucose index as simple marker associated with atherosclerotic cardiovascular disease in a tertiary care hospital in Pakistan
Triglyceride- glucose index as simple marker associated with atherosclerotic cardiovascular disease in a tertiary care hospital in Pakistan
medRxiv - The Preprint Server for Health Sciences
Long-gap esophageal atresia: gastric transposition or esophageal lengthening with delayed primary anastomosis? A systematic review
Long-gap esophageal atresia: gastric transposition or esophageal lengthening with delayed primary anastomosis? A systematic review
This study aims to evaluate different surgical approaches to long-gap esophageal atresia (LGEA) with or without tracheoeso...
Impact of prosthetic rehabilitation on oral health-related quality of life of Saudi Adults: A prospective observational study with pre–post design
Impact of prosthetic rehabilitation on oral health-related quality of life of Saudi Adults: A prospective observational study with pre–post design
Available online 23 April 2024Author links open overlay panel, , , , , , AbstractThis study aimed to assess the impact of ...
No benefit of β-blockers after myocardial infarction with preserved ejection fraction
In the REDUCE-AMI trial, the use of β-blockers in patients with acute myocardial infarction (MI) who have undergone e...
Benefits of ninerafaxstat in non-obstructive hypertrophic cardiomyopathy
Benefits of ninerafaxstat in non-obstructive hypertrophic cardiomyopathy
According to data from the IMPROVE-HCM trial, ninerafaxstat is well tolerated by patients with symptomatic non-obstructive...
Heart pump increases survival in STEMI-related cardiogenic shock
Heart pump increases survival in STEMI-related cardiogenic shock
Data from the DanGer Shock trial demonstrate that implantation of a microaxial flow pump in patients with ST-segment eleva...
RNA-based therapies targeting APOC3 lower triglyceride levels in patients with hypertriglyceridaemia
RNA-based therapies targeting APOC3 lower triglyceride levels in patients with hypertriglyceridaemia
Three randomized clinical trials presented at ACC.24 demonstrate that olezarsen and plozasiran, RNA-based therapies that t...
Strategies for the delivery of sex-based equity in cardiovascular clinical trials
The under-representation of women in cardiovascular clinical trials persists across participant, clinician and research ro...
Feasibility and utility of a combined nasogastric-tube-and-string-test device for bacteriologic confirmation of pulmonary tuberculosis in young children
Feasibility and utility of a combined nasogastric-tube-and-string-test device for bacteriologic confirmation of pulmonary tuberculosis in young children
For microbiological confirmation of pediatric pulmonary tuberculosis (PTB), gastric aspirates (GA) are often operationally...
Candida albicans cDNA library screening reveals novel potential diagnostic targets for invasive candidiasis
Candida albicans cDNA library screening reveals novel potential diagnostic targets for invasive candidiasis
Volume 109, Issue 3, July 2024, 116311Author links open overlay panel, , , , , , Highlights•Candida albicans germ tube ant...
A guide to precise measurements of isotope abundance by ESI-Orbitrap MS
A guide to precise measurements of isotope abundance by ESI-Orbitrap MS
Stable isotopes of carbon, hydrogen, nitrogen, oxygen and sulfur are widespread in nature. Nevertheless, their relative ab...
The Impact of Sesame Oil on Postpartum After-Pain in Multiparous Women: A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial
The Impact of Sesame Oil on Postpartum After-Pain in Multiparous Women: A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial
The contraction and expansion of the uterus following childbirth are known to cause postpartum cramps (Dashe, Bloom et al....
Surface photovoltage microscopy for mapping charge separation on photocatalyst particles
Surface photovoltage microscopy for mapping charge separation on photocatalyst particles
Solar-driven photocatalytic reactions offer a promising route to clean and sustainable energy, and the spatial separation ...
Rosa canina and Cancer: Which Evidence?
Rosa canina and Cancer: Which Evidence?
The Rosa genus (Rosaceae family) includes more than 260 species, and almost all species are seen in the Northern hemispher...
A Novel Four-Gene Signature Based on Nonsense-Mediated RNA Decay for Predicting Prognosis in Hepatocellular Carcinoma: Bioinformatics Analysis and Functional Validation
A Novel Four-Gene Signature Based on Nonsense-Mediated RNA Decay for Predicting Prognosis in Hepatocellular Carcinoma: Bioinformatics Analysis and Functional Validation
Presenting an innovative nonsense-mediated RNA decay risk model for predicting hepatocellular carcinoma prognosis
Clinical Characteristics of Non-B and Non-C Biopsy-Proven Primary Liver Cancers in an HBV- Endemic Area: A Retrospective Study
Clinical Characteristics of Non-B and Non-C Biopsy-Proven Primary Liver Cancers in an HBV- Endemic Area: A Retrospective Study
Exploring the distribution of probable causes and clinical characteristics of non-B and non-C (NBNC) primary liver cancer ...
Dispersion-engineered metasurfaces for high-sensitivity color image sensors
Dispersion-engineered metasurfaces for high-sensitivity color image sensors
Increasing the sensitivity of image sensors is a major challenge for current imaging technology. Researchers are tackling ...
Evaluation of in silico tools for variant classification in missense variants of solid cancer with actionable genetic targets
Evaluation of in silico tools for variant classification in missense variants of solid cancer with actionable genetic targets
medRxiv - The Preprint Server for Health Sciences
Reservoir computing for a MEMS mirror-based laser beam control on FPGA
Reservoir computing for a MEMS mirror-based laser beam control on FPGA
In this paper, a small-world network-based reservoir computing (SWN-RC) is introduced to a micro-electromechanical system ...
Machine Learning-driven Histotype Diagnosis of Ovarian Carcinoma: Insights from the OCEAN AI Challenge
Machine Learning-driven Histotype Diagnosis of Ovarian Carcinoma: Insights from the OCEAN AI Challenge
medRxiv - The Preprint Server for Health Sciences
Three patterns link brain organization to genes in health and disease
Three patterns link brain organization to genes in health and disease
Gene expression in the human cortex is shown to exhibit a generalizable three-component architecture that reflects neurona...
The associations of fatty acids related dietary patterns with overweight and obesity among Chinese children
The associations of fatty acids related dietary patterns with overweight and obesity among Chinese children
Childhood overweight and obesity is becoming an emerging face of malnutrition. The aims of this study were to develop fatt...
Enhancing Genetic Association Power in Endometriosis through Unsupervised Clustering of Clinical Subtypes Identified from Electronic Health Records
Enhancing Genetic Association Power in Endometriosis through Unsupervised Clustering of Clinical Subtypes Identified from Electronic Health Records
medRxiv - The Preprint Server for Health Sciences
Spontaneous acute-onset conus medullaris or cauda equina syndrome: beware of spinal acute subdural hematoma
Spontaneous acute-onset conus medullaris or cauda equina syndrome: beware of spinal acute subdural hematoma
Hoeritzauer I, Carson A, Statham P, Panicker JN, Granitsiotis V, Eugenicos M, Summers D, Demetriades AK, Stone J (2021) Sc...
SARS and synapses
SARS and synapses
SARS-CoV-2 infection can be associated with ‘brain fog’ and persistent neurologic disease, especially in the e...
Age and sex influence antibody profiles associated with tuberculosis progression
Age and sex influence antibody profiles associated with tuberculosis progression
Antibody features vary with tuberculosis (TB) disease state. Whether clinical variables, such as age or sex, influence ass...
Imaging manifestations of papillary glioneuronal tumors
Imaging manifestations of papillary glioneuronal tumors
To analyse the imaging findings of papillary glioneuronal tumors (PGNTs), in order to improve the accuracy of preoperative...
Elevated skull fractures: an institutional experience and individual participant data meta-analysis
Elevated skull fractures: an institutional experience and individual participant data meta-analysis
Elevated skull fracture (ESF) is a rare but potentially life-threatening type of skull fracture. The literature on this to...
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