aNeuroscience Institute, Section of Cagliari, National Research Council of Italy, Monserrato

bCagliari Pharmacological Research, Cagliari, Italy

*Current affiliation: Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA

Received 7 October 2021 Accepted as revised 7 December 2021

Correspondence to Dr. Giancarlo Colombo, Neuroscience Institute, Section of Cagliari, National Research Council of Italy, S.S. 554, km. 4,500, I-09042 Monserrato (CA), Italy, E-mail: [email protected]