Dendrimer nanoplatforms for veterinary medicine applications: a concise overview

Elsevier

Available online 6 January 2022

Drug Discovery TodayHighlights•

The sick animal is indeed a threat to man.

Dendrimer nanoplatforms can be used for veterinary medicine applications.

Foot and mouth disease, swine fever, HCA, rabies, and H9N2 avian influenza virus.

Intramuscular, subcutaneous, intravenous, and intraperitoneal routes of administrations are used.

Abstract

Within the nanoparticle (NP) space, dendrimers are becoming increasingly important in the field of nanomedicine, not only to treat human diseases, but also in veterinary medicine, which represents a new therapeutic approach. Major applications include using dendrimers to tackle highly contagious foot-and-mouth disease virus (FMDV) and swine fever virus (SFV) in pigs, FMDV in cattle, hypothermic circulatory arrest (HCA) in dogs, rabies, and H9N2 avian influenza virus in chickens. As we review here, intramuscular (im) subcutaneous (sc), intravenous (iv), and intraperitoneal (ip) routes of administration can be used for the successful application of dendrimers in animals.

Teaser. We discuss opportunities to develop dendrimer nanoplatforms for veterinary medicine applications.

Keywords

nanomedicine

dendrimers

veterinary medicine

foot and mouth disease

swine fever

hypothermic circulatory arrest

H9N2 avian influenza

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