Nitric oxide synthase-2 (CCTTT)n polymorphism is associated with local gene expression and clinical manifestations in patients with chronic rhinosinusitis

1. Lundberg, JON, Farkas-Szallasi, T, Weitzberg, E, et al. High nitric oxide production in human paranasal sinuses. Nat Med 1995; 1(4): 370–373.
Google Scholar | Crossref | Medline2. Lundberg, JO, Weitzberg, E. Nasal nitric oxide in man. Thorax 1999; 54(10): 947–952.
Google Scholar | Crossref | Medline3. Maniscalco, M, Sofia, M, Pelaia, G. Nitric oxide in upper airways inflammatory diseases. Inflamm Res 2007; 56(2): 58–69.
Google Scholar | Crossref | Medline4. Jain, B, Rubinstein, I, Robbins, RA, et al. Modulation of airway epithelial cell ciliary beat frequency by nitric oxide. Biochem Biophys Res Commun 1993; 191(1): 83–88.
Google Scholar | Crossref | Medline5. Weitzberg, E, Lundberg, JO. Humming greatly increases nasal nitric oxide. Am J Respir Crit Care Med 2002; 166(2): 144–145.
Google Scholar | Crossref | Medline6. Nathan, C, Xie, QW. Nitric oxide synthases: roles, tolls, and controls. Cell 1994; 78(6): 915–918.
Google Scholar | Crossref | Medline7. Sharma, JN, Al-Omran, A, Parvathy, SS. Role of nitric oxide in inflammatory diseases. Inflammopharmacology 2007; 15(6): 252–259.
Google Scholar | Crossref | Medline8. Cinelli, MA, Do, HT, Miley, GP, et al. Inducible nitric oxide synthase: regulation, structure, and inhibition. Med Res Rev 2020; 40(1): 158–189.
Google Scholar | Crossref | Medline9. Alderton, WK, Cooper, CE, Knowles, RG. Nitric oxide synthases: structure, function and inhibition. Biochem J 2001; 357(Pt 3): 593–615.
Google Scholar | Crossref | Medline | ISI10. Kone, BC, Kuncewicz, T, Zhang, W, et al. Protein interactions with nitric oxide synthases: controlling the right time, the right place, and the right amount of nitric oxide. Am J Physiol Renal Physiol 2003; 285(2): F178–F190.
Google Scholar | Crossref | Medline11. Stuehr, DJ, Haque, MM. Nitric oxide synthase enzymology in the 20 years after the Nobel Prize. Br J Pharmacol 2019; 176(2): 177–188.
Google Scholar | Crossref | Medline12. Avila, PC, Schleimer, RP. Airway epithelium. Allergy and Allergic Diseases. 2nd ed.. Bridgewater, NJ: Wiley, 2008, pp. 366–397.
Google Scholar | Crossref13. Xu, W, Charles, IG, Liu, L, et al. Molecular cloning and structural organization of the human inducible nitric oxide synthase gene (NOS2). Biochem Biophys Res Commun 1996; 219(3): 784–788.
Google Scholar | Crossref | Medline14. Qidwai, T, Jamal, F. Inducible nitric oxide synthase (iNOS) gene polymorphism and disease prevalence. Scand J Immunol 2010; 72(5): 375–387.
Google Scholar | Crossref | Medline15. Burgner, D, Usen, S, Rockett, K, et al. Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria. Hum Genet 2003; 112(4): 379–386.
Google Scholar | Crossref | Medline16. Warpeha, KM, Xu, W, Liu, L, et al. Genotyping and functional analysis of a polymorphic (CCTTT)(n) repeat of NOS2A in diabetic retinopathy. FASEB J 1999; 13(13): 1825–1832.
Google Scholar | Crossref | Medline17. Haruna, S, Otori, N, Moriyama, H, et al. Olfactory dysfunction in sinusitis with infiltration of numerous activated eosinophils. Auris Nasus Larynx 2006; 33(1): 23–30.
Google Scholar | Crossref | Medline18. Takeno, S, Hirakawa, K, Ishino, T. Pathological mechanisms and clinical features of eosinophilic chronic rhinosinusitis in the Japanese population. Allergol Int 2010; 59(3): 247–256.
Google Scholar | Crossref | Medline19. Nakayama, T, Yoshikawa, M, Asaka, D, et al. Mucosal eosinophilia and recurrence of nasal polyps - new classification of chronic rhinosinusitis. Rhinology 2011; 49(4): 392–396.
Google Scholar | Crossref | Medline20. Fujieda, S, Imoto, Y, Kato, Y, et al. Eosinophilic chronic rhinosinusitis. Allergol Int 2019; 68(4): 403–412.
Google Scholar | Crossref | Medline21. Fokkens, WJ, Lund, VJ, Mullol, J, et al. European position paper on rhinosinusitis and nasal polyps 2012. Rhinol Suppl 2012; 23: 3 p preceding table of contents, 1-298.
Google Scholar22. Tokunaga, T, Sakashita, M, Haruna, T, et al. Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study. Allergy 2015; 70(8): 995–1003.
Google Scholar | Crossref | Medline23. Sato, S, Wang, X, Saito, J, et al. Exhaled nitric oxide and inducible nitric oxide synthase gene polymorphism in Japanese asthmatics. Allergol Int 2016; 65(3): 300–305.
Google Scholar | Crossref | Medline24. Lund, VJ, Kennedy, DW. Staging for rhinosinusitis. Otolaryngol Head Neck Surg 1997; 117(3 Pt 2): S35–S40.
Google Scholar | SAGE Journals | ISI25. Morley, AD, Sharp, HR. A review of sinonasal outcome scoring systems - which is best? Clin Otolaryngol 2006; 31(2): 103–109.
Google Scholar | Crossref | Medline26. Parasher, AK, Kidwai, SM, Konuthula, N, et al. The role of doxycycline in the management of chronic rhinosinusitis with nasal polyps. Am J Otolaryngol 2019; 40(4): 467–472.
Google Scholar | Crossref | Medline27. Pascual, M, Sanz, C, Isidoro-García, M, et al. (CCTTT)n polymorphism of NOS2A in nasal polyposis and asthma: a case-control study. J Investig Allergol Clin Immunol 2008; 18(4): 239–244.
Google Scholar | Medline28. Negi, VS, Mariaselvam, CM, Misra, DP, et al. Polymorphisms in the promoter region of iNOS predispose to rheumatoid arthritis in south Indian Tamils. Int J Immunogenet 2017; 44(3): 114–121.
Google Scholar | Crossref | Medline29. Hsu, LA, Yeh, YH, Chen, WJ, et al. Association evidence of CCTTT repeat polymorphism in the iNOS promoter and the risk of atrial fibrillation in Taiwanese. Sci Rep 2017; 7: 42388.
Google Scholar | Crossref | Medline30. Hersberger, M, Bonhoeffer, S, Rampini, SK, et al. CCTTT-repeat polymorphism of the inducible nitric oxide synthase is not associated with HIV pathogenesis. Clin Exp Immunol 2004; 137(3): 566–569.
Google Scholar | Crossref | Medline31. Konno, S, Hizawa, N, Yamaguchi, E, et al. (CCTTT)n repeat polymorphism in the NOS2 gene promoter is associated with atopy. J Allergy Clin Immunol 2001; 108(5): 810–814.
Google Scholar | Crossref | Medline32. Batra, J, Pratap Singh, T, Mabalirajan, U, et al. Association of inducible nitric oxide synthase with asthma severity, total serum immunoglobulin E and blood eosinophil levels. Thorax 2007; 62(1): 16–22.
Google Scholar | Crossref | Medline33. Hirai, K, Shirai, T, Suzuki, M, et al. Association between (CCTTT)n repeat polymorphism in NOS2 promoter and asthma exacerbations. J Allergy Clin Immunol 2018; 142(2): 663–665.e3.
Google Scholar | Crossref | Medline34. Xu, W, Humphries, S, Tomita, M, et al. Survey of the allelic frequency of a NOS2A promoter microsatellite in human populations: assessment of the NOS2A gene and predisposition to infectious disease. Nitric Oxide 2000; 4(4): 379–383.
Google Scholar | Crossref | Medline35. Society, AT, Society, ER. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med 2005; 171(8): 912–930.
Google Scholar | Crossref | Medline36. Dweik, RA, Boggs, PB, Erzurum, SC, et al. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med 2011; 184(5): 602–615.
Google Scholar | Crossref | Medline | ISI37. Takeno, S, Taruya, T, Ueda, T, et al. Increased exhaled nitric oxide and its oxidation metabolism in eosinophilic chronic rhinosinusitis. Auris Nasus Larynx 2013; 40(5): 458–464.
Google Scholar | Crossref | Medline38. Taruya, T, Takeno, S, Kubota, K, et al. Comparison of arginase isoform expression in patients with different subtypes of chronic rhinosinusitis. J Laryngol Otol 2015; 129(12): 1194–1200.
Google Scholar | Crossref | Medline39. Lundberg, JO, Maniscalco, M, Sofia, M, et al. Humming, nitric oxide, and paranasal sinus obstruction. JAMA 2003; 289(3): 302–303.
Google Scholar | Crossref | Medline40. Lindberg, S, Cervin, A, Runer, T. Nitric oxide (NO) production in the upper airways is decreased in chronic sinusitis. Acta Otolaryngol 1997; 117(1): 113–117.
Google Scholar | Crossref | Medline41. Weschta, M, Deutschle, T, Riechelmann, H. Nasal fractional exhaled nitric oxide analysis with a novel hand-held device. Rhinology 2008; 46(1): 23–27.
Google Scholar | Medline42. Ragab, SM, Lund, VJ, Saleh, HA, et al. Nasal nitric oxide in objective evaluation of chronic rhinosinusitis therapy. Allergy 2006; 61(6): 717–724.
Google Scholar | Crossref | Medline43. Noda, N, Takeno, S, Fukuiri, T, et al. Monitoring of oral and nasal exhaled nitric oxide in eosinophilic chronic rhinosinusitis: a prospective study. Am J Rhinol Allergy 2012; 26(4): 255–259.
Google Scholar | SAGE Journals44. Kidoguchi, M, Yoshida, K, Noguchi, E, et al. Association between the NOS2 pentanucleotide repeat polymorphism and risk of postoperative recurrence of chronic rhinosinusitis with nasal polyps in a Japanese population. Allergol Int 2020; 69(4): 619–621.
Google Scholar | Crossref | Medline45. Faghani, M, Keshavars, P, Sharafshah, A, et al. TNF-alpha G/A308 polymorphism association with nasal polyposis in North part of Iran. Eur Arch Otorhinolaryngol 2018; 275(9): 2253–2257.
Google Scholar | Crossref | Medline

留言 (0)

沒有登入
gif