Clown Nose: A Rare Hypopharyngeal Cancer Metastasis

1. Krathen, RA, Orengo, IF, Rosen, T. Cutaneous metastasis: a meta-analysis of data. South Med J. 2003;96(2):164-167. doi:10.1097/01.SMJ.0000053676.73249.E5.
Google Scholar | Crossref | Medline2. Soyer, HP, Cerroni, L, Smolle, J, Kerl, H. “Clown-Nase”–hautmetastase eines mammakarzinoms [“clown nose”–skin metastasis of breast cancer]. Z Hautkr. 1990;65(10):929-931.
Google Scholar | Medline3. Amin, M, Edge, S, Greene, F, et al. AJCC Cancer Staging Manual. 8th ed. New York: Springer International Publishing: American Joint Commission on Cancer; 2017.
Google Scholar | Crossref4. Duprez, F, Berwouts, D, De Neve, W, et al. Distant metastases in head and neck cancer. Head Neck. 2017;39(9):1733-1743. doi:10.1002/hed.24687.
Google Scholar | Crossref | Medline5. Pitman, KT, Johnson, JT. Skin metastases from head and neck squamous cell carcinoma: Incidence and impact. Head Neck. 1999;21(6):560-565. doi:10.1002/(sici)1097-0347(199909)21:6<560::aid-hed10>3.0.co;2-q.
Google Scholar | Crossref | Medline6. Spector, JG, Sessions, DG, Haughey, BH, et al. Delayed regional metastases, distant metastases, and second primary malignancies in squamous cell carcinomas of the larynx and hypopharynx. Laryngoscope. 2001;111(6):1079-1087. doi:10.1097/00005537-200106000-00028.
Google Scholar | Crossref | Medline7. Gault, D, Subbuswamy, S. Metastatic tumours of the nasal tip. Br J Plast Surg. 1985;38(4):570-574. doi:10.1016/0007-1226(85)90023-2.
Google Scholar | Crossref | Medline8. De Simoni, I, Iacovelli, P, Lunghi, F, Peris, K, Chimenti, S. “Clown nose” as a first manifestation of lung carcinoma. Acta Derm Venereol. 1997;77(5):406-407. doi:10.2340/0001555577406407.
Google Scholar | Crossref | Medline9. Gal, TJ, Kerschner, JE. Pulmonary metastasis to the nasal tip. Otolaryngol Head Neck Surg. 1997;117(1):139. doi:10.1016/S0194-5998(97)70226-2.
Google Scholar | Crossref | Medline10. Vieira Mota, A, Correia, O, Resende, C, Azevedo, F, Mesquita Guimarães, J. Nasal tip metastasis revealing a Pancoast tumour. Br J Dermatol. 1998;138(3):559-560. doi:10.1046/j.1365-2133.1998.02156.x.
Google Scholar | Crossref | Medline11. Camarasa Escrig, A, Chiner Vives, E, Sancho Chust, JN. “Nariz de payaso” como manifestación inicial de un carcinoma epidermoide de pulmón. Arch Bronconeumol. 2009;45(1):60-61. doi:10.1016/j.arbres.2008.02.003.
Google Scholar | Crossref | Medline12. Marcoval, J, Martínez-Molina, L, Bonfill-Ortí, M, Valentí-Medina, F. “Clown nose” as first manifestation of squamous cell carcinoma of the lung. J Dermatol Case Rep. 2017;11(1):9-11. doi:10.3315/jdcr.2017.1241.
Google Scholar | Crossref | Medline13. Fu, Z, Liu, M, Zhang, J, Li, Z, Li, Q. Nasal-tip metastasis on 18F-FDG PET/CT scan in a patient with squamous lung carcinoma. Clin Nucl Med. 2017;42(6):478-479. doi:10.1097/RLU.0000000000001597.
Google Scholar | Crossref | Medline14. Zhu, X, Chen, J, Yang, F, Tang, C. Multiple sites of soft-tissue metastases secondary to lung cancer: a case report. Medicine (Baltimore). 2019;98(49):e18162. doi:10.1097/MD.0000000000018162.
Google Scholar | Crossref | Medline15. Bolewska, A, Słowińska, M, Błońska, A, et al. Tumor of the nose – a rare manifestation of a metastatic lung cancer. Clin Cosmet Invest Dermatol. 2021;14(May):1311-1318. doi:10.2147/ccid.s318748.
Google Scholar | Crossref | Medline16. Fiorio, LM, Diniz, LM, Lucas, EA. Cutaneous metastasis on the nasal tip: first clinical sign of pulmonary carcinoid tumor. An Bras Dermatol. 2021;96(5):578-580. doi:10.1016/j.abd.2021.03.002.
Google Scholar | Crossref | Medline17. Chau, C, Siu, W, Li, M. Nasal tip metastasis from esophageal carcinoma. Can J Surg. 2002;45(3):224-225.
Google Scholar | Medline18. Yathiraj, P, Patil, A, Ghosh-Laskar, S. Nasal mucosal metastasis in a case of carcinoma esophagus: case report and review of literature. J Cancer Res Therapeut. 2015;11(3):655. doi:10.4103/0973-1482.139393.
Google Scholar | Crossref | Medline19. Ledderose, GJ, Englhard, AS. Isolated nasal tip metastasis from esophageal squamous cell carcinoma: case report and literature review. Case Rep Otolaryngol. 2015;2015:1-4. doi:10.1155/2015/246094.
Google Scholar | Crossref20. Dong, A, Zuo, C, Wang, Y, Zhai, Z, Wen, W. Isolated nasal tip metastasis from esophageal squamous cell carcinoma. Clin Nucl Med. 2015;40(1):65-67. doi:10.1097/RLU.0000000000000387.
Google Scholar | Crossref | Medline21. Friederich, H, Lüders, G. Basaliomartige hämatogene Fernmetastase der Nasenspitze als Frühzeichen allgemeiner Metastasierung bei Mammacarcinom [Basalioma-like hematogenic dital metastasis of the nose tip as an early sign of generalized metastazing in breast carcinoma]. Z Haut-Geschlechtskr. 1968;43(1):1-8.
Google Scholar | Medline22. Kohli, PS, Soni, NK. Nasal tip metastasis: an unusual site and mode of spread in anaplastic thyroid carcinoma. Indian J Otolaryngol Head Neck Surg. 2008;60(3):269-270. doi:10.1007/s12070-008-0039-4.
Google Scholar | Crossref | Medline23. Yao, S, Lee, C, Chiu, C, Fan, Y, Huang, W. Follicular thyroid cancer with nose-tip metastasis and 131I uptake. Clin Nucl Med. 2020;45(10):441-442.
Google Scholar | Crossref24. Itin, PH, Heitzmann, F, Stamm, B. Metastasis to the nasal tip from a cervical carcinoma. Dermatology. 1999;199(2):171-173. doi:10.1159/000018231.
Google Scholar | Crossref | Medline25. Lee, G, Lorenz, H, Mohan, S. A rare case of mistaken identity: metastatic hepatocellular carcinoma to the nose. J Surg Case Reports. 2010;2010(4):3. doi:10.1093/jscr/2010.4.3.
Google Scholar | Crossref26. Mukherjee, D . Choriocarcinoma of the nose. Ann Otol Rhinol Laryngol. 1978;87(2 Pt 1):257-259.
Google Scholar | SAGE Journals27. Cesinaro, A, Maiorana, A, Annessi, G, Collina, G. Cutaneous metastasis of chordoma. Am J Dermatopathol. 1995;17(6):603-605. doi:10.1097/00000372-199512000-00014.
Google Scholar | Crossref | Medline28. Kocak, Z, Uygun, K, Uzal, M, Cicin, I, Yalcin, O. Unusual metastatic site in a case of carcinoma of the hypopharynx: nasal tip. J Otolaryngol. 2005;34(4):250-252. doi:10.2310/7070.2005.34409.
Google Scholar | Crossref | Medline29. Shindo, M, Yoshida, Y, Tominaga, K, Yamamoto, O. Skin metastasis of hypopharyngeal carcinoma to the nasal tip. Yonago Acta Med. 2013;56(2):57-58.
Google Scholar | Medline30. Shvili, Y, Talmi, YP, Gal, R, Kessler, E, Kolkov, Z, Zohar, Y. Basaloid-squamous carcinoma of larynx metastatic to the skin of the nasal tip. J Cranio-Maxillofacial Surg. 1990;18(7):322-324. doi:10.1016/S1010-5182(05)80541-4.
Google Scholar | Crossref | Medline31. Koutis, EV, Assimakopoulos, DA, Doukas, MG, Zinovieva, I. A rare nasal tip skin metastasis of a basaloid squamous cell carcinoma of the larynx. Am J Med. 2008;121(9):e3-e4. doi:10.1016/j.amjmed.2008.04.029.
Google Scholar | Crossref | Medline32. Aneiros-Fernandez, J, Arias-Santiago, S, Garcia-Lopez, C, O’Valle, F. Disfiguring basal cell carcinoma of the nose (“clown nose”). Ear Nose Throat J. 2012;91(1):26-27. doi:10.1177/014556131209100121.
Google Scholar | SAGE Journals33. Colletti, G, Allevi, F, Moneghini, L, Palvarini, M. Clown nose: a case of disfiguring nodular squamous cell carcinoma of the face. BMJ Case Rep. 2014;2014:bcr2013200471. doi:10.1136/bcr-2013-200471.
Google Scholar | Crossref | Medline34. Zhao, B, Chen, L, Liao, J, Xie, Z, Lei, X, Shen, Z. Update of clown nose-like Lesion, a underrecognized manifestation of metastatic malignancies and genetic cancer predisposition syndromes. Front Med. 2021;8(May):1-9. doi:10.3389/fmed.2021.673336.
Google Scholar | Crossref

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