Cartilage Repair

In article number 2101127 by Lewis W. Francis, Francesca Taraballi, and co-workers, a biomimetic immune tuning scaffold is implanted in a full-thickness chondral defect in rabbits. The early inflammatory infiltrates changed in the treated animals resulting in a better cartilage homeostasis at longer timepoints. This work represents the first approach of tuning the inflammatory reaction with a bulk material to achieve a better regeneration in cartilage.