Ultrastructural investigation on pseudo Chediak–Higashi abnormality in acute lymphoblastic leukemia: A case report

Early View e29541

LETTER TO THE EDITOR

Jing Liu,

Jing Liu

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Search for more papers by this authorShu-Xu Dong,

Shu-Xu Dong

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Search for more papers by this authorYing Li,

Ying Li

Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in Central Nervous System, Tianjin Medical University General Hospital, Ministry of Education, Tianjin, China

Search for more papers by this authorYi-Dan Xu,

Yi-Dan Xu

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Search for more papers by this authorYong-Xin Ru,

Corresponding Author

Yong-Xin Ru

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Correspondence

Yong-Xin Ru, Department of Electron Microscopy, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.

Email: ruyongxin@126.com

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Share on No abstract is available for this article. Filename Description pbc29541-sup-0001-figureS1.tif1.9 MB Supporting Figure S1 Flow cytometry results of the patient. (A) The total number of cells are set goal as P1. (B) The cells in (A) are divided into several segments according to the expression of CD45 and are set goals as P2, P4, P5, P6, and P7. (C) The cell numbers and corresponding proportions in different populations. (D) The cells in P10 are moderately positive for CD34, but negative for CD117. (E) The cells in P10 are moderately positive for HLA-DR and CD34. (F) The cells are moderately positive for CD34 in P10 are weakly positive for CD38 pbc29541-sup-0002-figureS2.tif2.1 MB Supporting Figure S2 Flow cytometry results of the patient. (A) The cells in P10 are moderately positive for CD13. (B) The cells in P10 are moderately positive for CD33. (C) The cells in P10 are moderately positive for CD19. (D) The cells were weakly positive for CD38 in P10 are strongly positive for CD10. (E) The cells in P10 are moderately positive for cCD79a and TDT. (F) The cells are moderately positive for cCD79a in P10 are negative for MPO pbc29541-sup-0003-figureS3.tif1.6 MB Supporting Figure S3 Flow cytometry results of the patient. (A) The target cells are set as goal C. (B) The lymphoblastic cells of patient in goal C are shown as goal D. (C) The different cell population are shown in goal D. (D) The cells in goal D are moderately positive for CD19. (E) The cells moderately positive for CD19 in goal D are negative for CD20. (F) The cells in goal D are negative for sIgM and cIgM. (G) The cells negative for cIgM in goal D are weakly positive for CD22

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