Neutrophil extracellular traps are associated with altered human pulmonary artery endothelial barrier function

1. Lorraine, BW, Matthay, MA. The acute respiratory distress syndrome. New Engl J Med 2000; 342: 1334–1349.
Google Scholar | Crossref | Medline2. Bellani, G, Lafey, JG, Pham, T, et al. Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA 2016; 315: 788–800.
Google Scholar | Crossref | Medline | ISI3. Papazian, L, Aubron, C, Brochard, L, et al. Formal guidelines: management of acute respiratory distress syndrome. Ann Intensive Care 2019; 9: 69.
Google Scholar | Crossref | Medline4. Brinkmann, V, Reichard, U, Goosmann, C, et al. Neutrophil extracellular traps kill bacteria. Science 2004; 303: 1532–1535.
Google Scholar | Crossref | Medline | ISI5. O'Brien, XM, Biron, BM, Reichner, JS. Consequences of extracellular trap formation in sepsis. Curr Opin Hematol 2017; 24: 66–71.
Google Scholar | Crossref | Medline6. Maruchi, Y, Tsuda, M, Mori, H, et al. Plasma myeloperoxidase-conjugated DNA level predicts outcomes and organ dysfunction in patients with septic shock. Crit Care 2018; 22: 176.
Google Scholar | Crossref | Medline7. Deng, Q, Pan, B, Alam, HB, et al. Citrullinated Histone H3 as a therapeutic target for endotoxic shock in mice. Front Immunol 2020; 10: 2957.
Google Scholar | Crossref | Medline8. tMcDonald, B, Davis, RP, Kim, SJ, et al. Platelets and neutrophil extracellular traps collaborate to promote intravascular coagulation during sepsis in mice. Blood 2017; 129: 1357–1367.
Google Scholar | Crossref | Medline9. Folco, EJ, Mawson, TL, Vromman, A, et al. Neutrophil extracellular traps induce endothelial cell activation and tissue factor production through interleukin-1α and cathepsin G. Arteriosclerosis, Thromb Vasc Biol 2018; 38: 1901–1912.
Google Scholar | Crossref | Medline10. Wang, H, Sha, LL, Ma, TT, et al. Circulating level of neutrophil extracellular traps is not a useful biomarker for assessing disease activity in antineutrophil cytoplasmic antibody-associated vasculitis. PLoS ONE 2016; 11: e0148197.
Google Scholar | Medline11. Middleton, EA, He, XY, Denorme, F, et al. Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome. Blood 2020; 136: 1169–1179.
Google Scholar | Crossref | Medline12. Zucoloto, AZ, Jenne, CN. Platelet-neutrophil interplay: insights into neutrophil extracellular trap (NET)-driven coagulation in infection. Front Cardiovasc Med 2019; 6: 85.
Google Scholar | Crossref | Medline13. Zhou, P, Li, T, Jin, J, et al. Interactions between neutrophil extracellular traps and activated platelets enhance procoagulant activity in acute stroke patients with ICA occlusion. EBioMedicine 2020; 53: 102671.
Google Scholar | Crossref | Medline14. Lefrançais, E, Mallavia, B, Zhuo, H, et al. Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury. JCI Insight 2018; 3: e98178.
Google Scholar | Crossref | Medline15. Twaddell, SH, Baines, KJ, Grainge, C, et al. The emerging role of neutrophil extracellular traps in respiratory disease. Chest 2019; 156: 4774–4782.
Google Scholar | Crossref16. Narasaraju, T, Yang, E, Samy, RP, et al. Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis. Am J Pathol 2011; 179: 199–210.
Google Scholar | Crossref | Medline | ISI17. Brinkmann, V, Laube, B, Abed, UA, et al. Neutrophil extracellular traps: how to generate and visualize them. J Visualized Experiments 2010; 36: 1724.
Google Scholar18. Hashiba, M, Huq, MA, Tomino, A, et al. Neutrophil extracellular traps in patients with sepsis. J Surg Res 2015; 194: 248–254.
Google Scholar | Crossref | Medline19. Kano, H, Huq, MA, Tsuda, M, et al. Sandwich ELISA for circulating myeloperoxidase- and neutrophil elastase-DNA complexes released from neutrophil extracellular traps. Adv Tech Biol Med 2016; 5: 1–7.
Google Scholar20. Breslin, JW, Sun, H, Xu, W, et al. Involvement of ROCK-mediated endothelial tension development in neutrophil-stimulated microvascular leakage. Am J Physiol Heart Circulatory Physiol 2006; 290: H741–H750.
Google Scholar | Crossref | Medline21. Lum, H, Malik, AB. Regulation of vascular endothelial barrier function. Am J Physiol 1994; 267: L223–L241.
Google Scholar | Medline | ISI22. Saffarzadeh, M, Juenemann, C, Queisser, MA, et al. Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones. PLoS One 2012; 7: e32366.
Google Scholar | Crossref | Medline | ISI23. Crocetti, L, Schepetkin, IA, Cilibrizzi, A, et al. Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase. J Med Chem 2013; 56: 6259–6272.
Google Scholar | Crossref | Medline24. Braster, Q, Roig, CS, Hartwig, H, et al. Inhibition of NET release fails to reduce adipose tissue inflammation in mice. PLoS One 2016; 11: e0163922.
Google Scholar | Crossref | Medline25. Lee, WL, Downey, GP. Neutrophil activation and acute lung injury. Curr Opin Crit Care 2001; 7: 1–7.
Google Scholar | Crossref | Medline26. Herold, S, Gabrielli, NM, Vadász, I. Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction. Am J Physiol Lung Cell Mol Physiol 2013; 305: L665–L681.
Google Scholar | Crossref | Medline | ISI27. Mikacenic, C, Moore, R, Dmyterko, V, et al. Neutrophil extracellular traps (NETs) are increased in the alveolar spaces of patients with ventilator-associated pneumonia. Crit Care 2018; 22: 358.
Google Scholar | Crossref | Medline28. Benatti, MN, Fabro, AT, Miranda, CH. Endothelial glycocalyx shedding in the acute respiratory distress syndrome after flu syndrome. J Intensive Care 2020; 8: 72.
Google Scholar | Crossref | Medline29. Schmidt, EP, Yang, Y, Janssen, WJ, et al. The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. Nat Med 2012; 18:1217–1223.
Google Scholar | Crossref | Medline | ISI30. Szabó, C, Ischiropoulos, H, Radi, R. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat Rev Drug Discov 2007; 6: 662–680.
Google Scholar | Crossref | Medline | ISI31. Lv, D, Xu, Y, Cheng, H, et al. A novel cell-based assay for dynamically detecting neutrophil extracellular traps-induced lung epithelial injuries. Exp Cell Res 2020; 394: 112101.
Google Scholar | Crossref | Medline32. Liu, S, Su, X, Pan, P, et al. Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury. Scientific Rep 2016; 6: 37252.
Google Scholar | Crossref | Medline33. Li, H, Zhou, X, Tan, H, et al. Neutrophil extracellular traps contribute to the pathogenesis of acid-aspiration-induced ALI/ARDS. Oncotarget 2017; 9: 1772–1784.
Google Scholar | Crossref | Medline34. Czaikoski, PG, Mota, JM, Nascimento, DC, et al. Neutrophil extracellular traps induce organ damage during experimental and clinical sepsis. PLoS One 2016; 11: e0148142.
Google Scholar | Crossref | Medline35. Veras, FP, Pontelli, MC, Silva, CM, et al. SARS-CoV-2-triggered neutrophil extracellular traps mediate COVID-19 pathology. J Exp Med 2020; 217: e20201129.
Google Scholar | Crossref | Medline36. Weber, AG, Chau, AS, Egeblad, M, et al. Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series. Mol Med 2020; 26: 91.
Google Scholar | Crossref | Medline37. Majewski, P, Majchrzak-Gorecka, M, Grygier, B, et al. Inhibitors of serine proteases in regulating the production and function of neutrophil extracellular traps. Front Immunol 2016; 7: 261.
Google Scholar | Crossref | Medline38. Knight, JS, Subramanian, V, O’Dell, AA, et al. Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus prone MRL/lpr mice. Ann Rheum Dis 2015; 74: 2199–2206.
Google Scholar | Crossref | Medline | ISI39. Lewis, HD, Liddle, J, Coote, JE, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol 2015; 11: 189–191.
Google Scholar | Crossref | Medline40. Wang, Y, Li, M, Stadler, S, et al. Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol 2009; 184: 205–213.
Google Scholar | Crossref | Medline | ISI41. Thiam, HR, Wong, SL, Qiu, R, et al. NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture. Proc Natl Acad Sci United States America 2020; 117: 7326–7337.
Google Scholar | Crossref | Medline42. Martinod, K, Fuchs, TA, Zitomersky, NL, et al. PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock. Blood 2015; 125: 1948–1956.
Google Scholar | Crossref | Medline43. Biron, BM, Chung, CS, Chen, Y, et al. PAD4 deficiency leads to decreased organ dysfunction and improved survival in a dual insult model of hemorrhagic shock and sepsis. J Immunol 2018; 200: 1817–1828.
Google Scholar | Medline44. Harris, ES, Nelson, WJ. VE-cadherin: at the front, center, and sides of endothelial cell organization and function. Curr Opin Cell Biol 2010; 22: 651–658.
Google Scholar | Crossref | Medline | ISI45. Wallez, Y, Huber, P. Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis. Biochim Biophys Acta 2008; 1778: 794–809.
Google Scholar | Crossref | Medline46. Cerutti, C, Ridley, AJ. Endothelial cell-cell adhesion and signaling. Exp Cell Res 2017; 358: 31–38.
Google Scholar | Crossref | Medline47. Amado-Azevedo, J, Valent, ET, Amerongen, GPVN. Regulation of the endothelial barrier function: a filum granum of cellular forces, Rho-GTPase signaling and microenvironment. Cell Tissue Res 2014; 355: 557–576.
Google Scholar | Crossref | Medline48. Lechuga, S, Ivanov, AI. Actin cytoskeleton dynamics during mucosal inflammation: a view from broken epithelial barriers. Curr Opin Physiol 2021; 19: 10–16.
Google Scholar | Crossref | Medline49. Xu, J, Zhang, X, Monestier, M, et al. Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury. J Immunol 2011; 187: 2626–2631. DOI: 10.4049/jimmunol.1003930.
Google Scholar | Crossref | Medline | ISI50. Von Brühl, ML, Stark, K, Steinhart, A,

留言 (0)

沒有登入
gif