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Intricate balance of dually-localized catalase modulates infectivity of Leptomonas seymouri (Kinetoplastea: Trypanosomatidae)
Intricate balance of dually-localized catalase modulates infectivity of Leptomonas seymouri (Kinetoplastea: Trypanosomatidae)
Available online 23 April 2024Author links open overlay panel, , , , , , , , , , , , , , , , , , , …Highlights•Catalase in...
Innovative insights: ITLN1 modulates renal injury in response to radiation
Innovative insights: ITLN1 modulates renal injury in response to radiation
Radiation-induced kidney injury is a common complication of radiotherapy for lower abdominal tumors, leading to significan...
Protective role of pretreatment with Anisodamine against sepsis-induced diaphragm atrophy via inhibiting JAK2/STAT3 pathway
Protective role of pretreatment with Anisodamine against sepsis-induced diaphragm atrophy via inhibiting JAK2/STAT3 pathway
There is an increasing tendency for sepsis patients to suffer from diaphragm atrophy as well as mortality. Therefore, redu...
Knockdown of KBTBD7 attenuates septic lung injury by inhibiting ferroptosis and improving mitochondrial dysfunction
Knockdown of KBTBD7 attenuates septic lung injury by inhibiting ferroptosis and improving mitochondrial dysfunction
Sepsis is a systemic infection response syndrome caused by pathogenic microorganisms entering the body and causing excessi...
RIP1 kinase inactivation protects against LPS-induced acute respiratory distress syndrome in mice
RIP1 kinase inactivation protects against LPS-induced acute respiratory distress syndrome in mice
Acute respiratory distress syndrome (ARDS), a severe form of acute lung injury (ALI), can result from various factors such...
CXCL4:NLRP3-mediated pyroptosis product that regulates cardiac fibrosis
CXCL4:NLRP3-mediated pyroptosis product that regulates cardiac fibrosis
VMC is a heart disease mainly caused by CVB3 (Coxsackie B Type 3) virus infection. In the early stages of infection, infla...
Immune targeting of filarial glutaredoxin through a multi-epitope peptide-based vaccine: A reverse vaccinology approach
Immune targeting of filarial glutaredoxin through a multi-epitope peptide-based vaccine: A reverse vaccinology approach
Deficiencies in the comprehension of immunobiological intricacies substantiate the enduring prevalence of lymphatic filari...
Mitochondrial-dependent oxidative phosphorylation is key for postnatal metabolic adaptation of alveolar macrophages in the lung
Mitochondrial-dependent oxidative phosphorylation is key for postnatal metabolic adaptation of alveolar macrophages in the lung
KeywordsAlveolar macrophagesmitochondrial transcription factor AMetabolic adaptationEndoplasmic reticulum stressAbbreviati...
Comprehensive study of the interplay between immunological and metabolic factors in hepatic steatosis
Comprehensive study of the interplay between immunological and metabolic factors in hepatic steatosis
A serious worldwide health concern is the pathophysiology of hepatic steatosis, which is defined by the build-up of extra ...
Cope with copper: From molecular mechanisms of cuproptosis to copper-related kidney diseases
Cope with copper: From molecular mechanisms of cuproptosis to copper-related kidney diseases
Cell death is a key process in both biological growth and development as well as in the progression of multiple diseases. ...
The quantity, function and anti-tumor effect of Mucosal associated invariant T cells in patients with bladder cancer
The quantity, function and anti-tumor effect of Mucosal associated invariant T cells in patients with bladder cancer
Bladder cancer (BC) ranks eleventh among all malignant tumors and stands out as one of the most common malignant tumors af...
Inpatient Cost Burdens of Treating Chronic Hepatitis B in US Hospitals: A Weighted Analysis of a National Database
Inpatient Cost Burdens of Treating Chronic Hepatitis B in US Hospitals: A Weighted Analysis of a National Database
This study evaluates the cost burdens of inpatient care for chronic hepatitis B (CHB). We aimed to stratify the patients b...
Acetyl-CoA-dependent ac4C acetylation promotes the osteogenic differentiation of LPS-stimulated BMSCs
Acetyl-CoA-dependent ac4C acetylation promotes the osteogenic differentiation of LPS-stimulated BMSCs
Bone marrow mesenchymal stem cells (BMSCs) are the progenitor cells of osteoblasts that play critical roles in mediating b...
Implications of innate lymphoid cells in oral diseases
Implications of innate lymphoid cells in oral diseases
Innate lymphoid cells (ILCs), which are independent of the regulation of recombination-activating genes and lack the expre...
ZAP facilitates NLRP3 inflammasome activation via promoting the oligomerization of NLRP3
ZAP facilitates NLRP3 inflammasome activation via promoting the oligomerization of NLRP3
The NOD-like receptor family protein 3 (NLRP3) is a member of the NLR family and an indispensable component of NLRP3 infla...
EFHD2 regulates T cell receptor signaling and modulates T helper cell activation in early sepsis
EFHD2 regulates T cell receptor signaling and modulates T helper cell activation in early sepsis
Sepsis 3.0 is defined as a dangerous organ malfunction elicited by an unregulated host reaction to infectious agents [1]. ...
Unveiling the role of FTO polymorphisms in predicting response to immune checkpoint inhibitors: A retrospective study
Unveiling the role of FTO polymorphisms in predicting response to immune checkpoint inhibitors: A retrospective study
The burgeoning ICIs have sparked an intense revolution in standard-of-antitumor practice. The cytotoxic T-lymphocyte–assoc...
Perspectives of genetic management strategy for inherited cardiovascular diseases in China
Perspectives of genetic management strategy for inherited cardiovascular diseases in China
1Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, West China Second University Ho...