Endometrial Stromal Expression of ER, PR, and B-Catenin Toward Differentiating Hyperplasia Diagnoses

1. Sanderson, PA, Critchley, HO, Williams, AR, et al. New concepts for an old problem: the diagnosis of endometrial hyperplasia. Hum Reprod Update. 2017;23(2):232–254.
Google Scholar | Medline2. Kurman, RJ, Kaminski, PF, Norris, HJ. The behavior of endometrial hyperplasia (1985) A long term study of ‘untreated hyperplasia‘ in 170 patients. Cancer. 1985;56(2):403–412.
Google Scholar | Crossref | Medline3. Tavassoli, FA, Devilee, P, eds (2003) World Health Organization Classification of Tumours of the Breast and Female Genital Organs. IARC Press 4. Mutter, GL . Endometrial intraepithelial neoplasia (EIN): will it bring order to chaos? The endometrial collaborative group. Gynaecol Oncol. 2000;76:287–290.
Google Scholar4. Kurman, R, Carcangiu, M, Herrington, C, Young, R eds. (2004) World Health Organization Classification of Tumours of Female Reproductive Organs. (Fourth ed). IARC Press 6. Allison, KH, Reed, SD, Voigt, LF, et al. Diagnosing endometrial hyperplasia: why is it so difficult to agree? Am J Surg Pathol. 2008;32:691–698.
Google Scholar5. Kane, SE, Hecht, JL. Endometrial intraepithelial neoplasia terminology in practice: 4-year experience at a single institution. Int J Gynecol Pathol. 2012;31:160–165.
Google Scholar | Crossref | Medline6. Trimble, CL, Method, M, Leitao, M, et al. Management of endometrial precancers. Obstet Gynecol. 2012;120:1160–1175.
Google Scholar | Crossref | Medline | ISI7. Wihuthayanon, W, Hewitt, SC, Orvis, GD, et al. Uterine epithelial estrogen receptor alpha is dispensable for proliferation but essential for complete biological and biochemical responses. Proc Natl Acad Sci USA. 2010;107:19272–19277.
Google Scholar | Crossref | Medline8. Montserrat, N, Mozos, A, Llobet, D, et al. Epithelial to mesenchymal transition in early stage endometrioid endometrial carcinoma. Hum Pathol. 2012;43:632–643.
Google Scholar | Crossref | Medline | ISI9. Senol, S, Sayar, I, Ceyran A, A, et al. Stromal clues in endometrial carcinoma: loss of expression of β-catenin, epithelial-mesenchymal transition regulators, and estrogen-progesterone receptor. Int J Gynecol Pathol. 2015;35:238–248.
Google Scholar | Crossref10. Brabletz, T, Jung, A, Reu, S, et al. Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by tumor environment. Proc Natl Acad Sci USA. 2001;98:10356–10361.
Google Scholar | Crossref | Medline | ISI11. Hu, K, Zhong, G, He, F. Expression of estrogen receptors ER alpha and ER beta in endometrial hyperplasia and adenocarcinoma. Int J Gynecol Cancer. 2008;15:537–341.
Google Scholar12. Bircan, S, Ensari, A, Ozturk, S, et al. Immunohistochemical analysis of c-myc, c-jun and estrogen receptor in normal, hyperplastic and neoplastic endometrium. Pathol Oncol Res. 2005;11:32–39.
Google Scholar | Crossref | Medline13. Schmalhofer, O, Brabletz, S, Brabletz, T. E-cadherin, beta-catenin and ZEB1 in malignant progression of cancer. Cancer Metastasis Rev. 2009;28:151–166.
Google Scholar | Crossref | Medline | ISI14. Ito, K, Utsonomiya, H, Yaegashi, N, et al. Biological roles of estrogen and progesterone in human endometrial carcinoma – new developments in potential endocrine therapy for endometrial cancer. Endocr J. 2007;54:667–679.
Google Scholar | Crossref | Medline | ISI15. Ovejuela, FJ, Romondetta, LM, Smith, J, et al. Estrogen and progesterone receptors and cyclooxygenase-2 expression in endometrial carcer, endometrial hyperplasia and normal endometrium. Gynecol Oncol. 2005;97:484–491.
Google Scholar16. Romagosa, C, Simonetti, S, Lopez-Vicente, L, et al. P16 (Ink4a) overexpression in cancer: a tumor suppressor gene associated with senescence and high grade tumors. Oncogene. 2011;30:2087–2097.
Google Scholar | Crossref | Medline | ISI17. Yoon, G, Won Koh, C, Yoon, N, et al. Stromal p16 expression is significantly increased in endometrial carcinoma. Oncotarget. 2017;8:4826–4836.
Google Scholar | Crossref | Medline18. Risberg, B, Karlsson, K, Abeler, V, et al. Dissociated expression of Bcl-2 and Ki-67 in endometrial lesions: diagnostic and histogenetic implications. Int J Gynecol Pathol. 2002;21:155–160.
Google Scholar | Crossref | Medline19. Vaskivuo, TE, Stenback, T, Tapanaineu, JS. Apoptosis and apoptosis-related factors Bcl-2, Bax tumor necrosis factor-alpha and NF KappaB in human endometrial hyperplasia and carcinoma. Cancer. 2002;95:1463–1471.
Google Scholar | Crossref | Medline | ISI20. Pieszynska, B, Wojtyla, KS, Zawrocki, A, et al. Analysis of PTEN estrogen receptor and progesterone receptor expression in endometrial hyperplasia using tissue microarray. Pol J Pathol. 2011;62:133–138.
Google Scholar | Medline21. Gabreaux, L, Roux, JP, Nevelaeu, A, et al. Correlation between the DNA global methylation status and progesterone receptor expression in normal endometrium, endometrioid adenocarcinoma and precursors. Virchows Arch. 2004;445:129–134.
Google Scholar | Medline

留言 (0)

沒有登入
gif