A diffusion tensor imaging MRI scan showing fractional anisotropy of the prefrontal cortex of a 7 week old pig, used to study the effect of cardiopulmonary bypass on developing brains. Increased cortical fractional anisotropy after severe injury due to cardiopulmonary bypass served as a measure of the impact on cortical maturation. See paper by Dhari and colleagues in this issue (pp. 913-926).