Vaccination remains the most effective means out of the COVID-19 pandemic. Data from randomised clinical trials demonstrated that COVID-19 vaccines, reduce severe COVID infections and prevent deaths1. However, there was initially an unexpectedly high rate of suspected allergic reactions to COVID-19 vaccines (for anaphylaxis 2.5-11.1 cases/million doses for the mRNA vaccines) compared with non-COVID-19 vaccines (1.3 cases/million doses) which caused considerable alarm,2,3, placing significant pressure on allergy centres. It also perpetuated fears circulating in the media about COVID-19 vaccines resulting in vaccine scepticism and hesitancy. Allergic reactions following vaccination may be due to any of the excipients (adjuvants, preservatives, emulsifiers, stabilizers etc.) 3. Polyethylene glycol (PEG) in mRNA COVID-19 vaccines (Pfizer-BioNTech, Moderna) remains the only likely IgE mediated allergenic suspect, but investigation has so far confirmed this in only one case4.