Safety Assessment of Keratin and Keratin-Derived Ingredients as Used in Cosmetics

1. Nikitakis, J, Lange, B. International Cosmetic Ingredient Dictionary and Handbook. 16th ed. Personal Care Products Council; 2016.
Google Scholar2. Elder, RL . Final report on the safety assessment of hydrolyzed collagen. Am Coll Toxicol. 1985;4(5):199–221.
Google Scholar | SAGE Journals3. Andersen, FA, Bergfeld, WF, Belsito, DV, et al. Final report of the safety assessment of cosmetic ingredients derived from zea mays (Corn). Int J Toxicol. 2011;30(Suppl 1):17S–39S.
Google Scholar | SAGE Journals4. Andersen, FA , ed. Annual review of cosmetic ingredient safety assessments - 2004/2005. Int J Toxicol. 2006;25(Suppl 2):1–89.
Google Scholar | Medline | ISI5. Andersen, FA , ed. Amended Final Report on the Safety Assessment of Oryza Sativa (Rice) Bran Oil, Oryza Sativa (Rice) Germ Oil, Rice Bran Acid, Oryza Sativa (Rice) Bran Wax, Hydrogenated Rice Bran Wax, Oryza Sativa (Rice) Bran Extract, Oryza Sativa (Rice) Extract, Oryza Sativa (Rice) Germ Powder, Oryza Sativa (Rice) Starch, Oryza Sativa (Rice) Bran, Hydrolyzed Rice Bran Extract, Hydrolyzed Rice Bran Protein, Hydrolyzed Rice Extract, and Hydrolyzed Rice Protein. Int J Toxicol. 2006;25(Suppl 2):91–120.
Google Scholar | Medline6. Johnson, WJ, Bergfeld, WF, Belsito, DV, et al. Safety Assessment of Silk Protein Ingredients as Used in Cosmetics. Cosmetic Ingredient Review; 2015.
Google Scholar7. Burnett, CL, Heldreth, B, Belsito, DV, et al. Safety Assessment of Soy Proteins and Peptides as Used in Cosmetics. Cosmetic Ingredient Review; 2015.
Google Scholar8. Burnett, CL, Heldreth, B, Boyer, I, et al. Safety Assessment of Hydrolyzed Wheat Protein and Hydrolyzed Wheat Gluten as Used in Cosmetics. Cosmetic Ingredient Review; 2014.
Google Scholar9. Chahal, S . Letter from Dr. Surinder Chahal concerning the CJR review of Keratin and Hydrolyzed Keratin. Unpublished data submitted by Personal Care Products Council; 2016.
Google Scholar10. Rouse, JG, Van Dyke, ME. A review of keratin-based biomaterials for biomedical applications. Materials. 2010;3(2):999–1014.
Google Scholar | Crossref | ISI11. Tonin, C, Aluigi, A, Varesano, A, Vineis, C.Keratin-Based Nanofibres. Kumar A.InTech; 2010:139–158.
Google Scholar | Crossref12. O’Neil, MJ , ed. The merck index. 15th ed. The Royal Society of Chemistry; 2013.
Google Scholar13. Hill, P, Brantley, H, Van Dyke, M.Some properties of keratin biomaterials: Kerateines. Biomaterials. 2010;31(4):585–593.
Google Scholar | Crossref | Medline | ISI14. Personal Care Products Council . Information on Hydrolyzed Keratin, Hydrolyzed Silk Protein, Hydrolyzed Elastin, Hydrolyzed Soy Protein, Hydrolyzed Milk Protein and Hydrolyzed Vegetable Protein. Unpublished data submitted by Personal Care Products Council; 7-3-2012:25.
Google Scholar15. Personal Care Products Council . Molecular Weights and Hydrolysis Method: Hydrolyzed Brazil Nut Protein, Hydrolyzed Hair Keratin, Hydrolyzed Keratin and Hydrolyzed Sweet Almond Protein. Unpublished data submitted by the Personal Care Products Council; 2012.
Google Scholar16. Personal Care Products Council . Method of Manufacture and Molecular Weights: Hydrolyzed Protein Ingredients. Unpublished data submitted by Personal Care Products Council; 5-14-2012:8.
Google Scholar17. Wortmann, FJ, Sendelbach, G, Popescu, C. Fundamental DSC investigations of α-keratinous materials as basis for the interpretation of specific effects of chemical, cosmetic treatments on human hair. J Cosmet Sci. 2007;58(4):311–317.
Google Scholar | Medline18. Vasconcelos, A, Freddi, G, Cavaco-Paulo, A. Biodegradable materials based on silk fibroin and keratin. Biomacromolecules. 2008;9(4):1299–1305.
Google Scholar | Crossref | Medline19. Chan, WW . A method for the complete S sulfonation of cysteine residues in proteins. Biochemistry. 1968;7(12):4247–4254.
Google Scholar | Crossref | Medline20. Mohd Amir, SNK, Gupta, A, Tuan Chik, SMS, Ahmad, K. Development of anti-ageing cream from chicken feathers. Res J Pharm Biol Chem Sci. 2014;5(6):389–393.
Google Scholar21. Arch Personal Care Products LP . Hydrokeratin AL-30 (Hydrolyzed Keratin) Manufacturing Procedure. Unpublished data submitted by Personal Care Products Council; 2012:8.
Google Scholar22. Personal Care Products Council . Hydrolyzed Keratin. Unpublished data submitted by Personal Care Products Council; 1-28-2016.
Google Scholar23. Active Concepts . Certificate of Origin (AC Keratin Hydrolysate SD - Powder Hydrolyzed Keratin from Sheep Wool). Unpublished data submitted by Personal Care Products Council; 2014.
Google Scholar24. Active Concepts . Certificate of Origin (AC Keratin Hydrolysate 30- Solution Hydrolyzed Keratin from Sheep Wool). Unpublished data submitted by Personal Care Products Council; 2015.
Google Scholar25. Active Concepts . Certificate of Origin (AC Cashmere Hydrolysate - solution Hydrolyzed Keratin from Goat Wool). Unpublished data submitted by Personal Care Products Council; 2015.
Google Scholar26. Anonymous . Summaries of Dermal and Ocular Irritation Tests of Hydrolyzed Protein Ingredients (Including Proteins Hydrolyzed to Amino Acids). Unpublished data submitted by Personal Care Products Council; 2012:4.
Google Scholar27. Personal Care Products Council . Soluble Keratin. Unpublished data submitted by Personal Care Products Council; 2016.
Google Scholar28. Strnad, P, Usachov, V, Debes, C, Gräter, F, Parry, DAD, Omary, MB. Unique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins. J Cell Sci. 2011;124(24):4221–4232.
Google Scholar | Crossref | Medline29. Food and Drug Administration (FDA) . Frequency of use of Cosmetic Ingredients. FDA Database. FDA; 2016.
Google Scholar30. Bremmer, HJ, Prud’homme de Lodder, LCH, Engelen, JGM. Cosmetics Fact Sheet: To assess the risks for the consumer; Updated version for ConsExpo 4. Report No. RIVM 320104001/2006; 2006:1–77.
Google Scholar31. Rothe, H, Fautz, R, Gerber, E, et al. Special aspects of cosmetic spray safety evaluations: Principles on inhalation risk assessment. Toxicol Lett. 2011;205(2):97–104.
Google Scholar | Crossref | Medline | ISI32. Rothe, H . Special Aspects of Cosmetic Spray Evalulation. Unpublished data presented at the 26 September CIR Expert Panel meeting. Washington, DC; 9-26-2011.
Google Scholar33. Johnsen, MA . The Influence of Particle Size. Spray Technology Marketing. 2004;14(11):24–27.
Google Scholar34. European Union. Regulation (EC) No . 1223/2009 of the European Parliament and of the Council of 30 November 2009 on Cosmetic Products. 2009. Internet site Accessed September 13, 2013. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2009:342:0059:0209:en:PDF
Google Scholar35. Scientific Committee on Consumer Products (SCCP) . Opinion on amino acids obtained by hydrolysis of human hair. 2005. Accessed 2-4-2016. Report No. SCCP/0894/05; http://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_o_005.pdf
Google Scholar36. Singaravelu, S, Ramanathan G Raja, MD, Barge, S, Sivagnanam, UT. Preparation and characterization of keratin-based biosheet from bovine horn waste as wound dressing material. Materi Lett. 2015;152:90–93.
Google Scholar | Crossref37. Noda, J, Imai, T, Kida, K, Otagiri, M. The physicochemical and biopharmaceutical properties of fragmented keratin as a new drug carrier. Biol Pham Bull. 1996;19(3):466–473.
Google Scholar | Crossref | Medline38. Barba, C, Mendez, S, Roddick-Lanzilotta, A, Kelly, R, Parra, JL, COderech, I. Wool peptide derivatives for hand care. J Cosmet Sci. 2007;58(2):99–107.
Google Scholar | Medline39. Consumer Product Testing Co . Primary Dermal Irritation in Rabbits; Primary Ocular Irritation in Rabbits; Acute Oral Toxicity in Rats (25% Hydrolyzed Keratin from Hoof Meal). Unpublished data submitted by the Personal Care Products Council; 1983.
Google Scholar40. Food and Drug Research Laboratories, Inc . Acute Oral Toxicity in Rats (20% Hydrolyzed Keratin from Hoof Meal). Unpublished data from the Personal Care Products Council; 1976.
Google Scholar41. Toxicol Laboratories Limited . Single dose Oral Toxicity Study in the Rat (20% Hydrolyzed Keratin from Hoof Meal). Unpublished data submitted by the Personal Care Products Council; 1986.
Google Scholar42. Fernandes, MM, Lima, CF, Loureiro, A, Gomes, AC, Cavaco-Paulo, A.Keratin-based peptide: Biological evaluation and strengthening properties on relaxed hair. Int J Cosmet Sci. 2012;34(4):338–346.
Google Scholar | Crossref | Medline43. BioReliance . Bacterial Reverse Mutation Assay Hydrolyzed Keratin (MW - 3,000 Da). BioReliance Study Number AA88DT.502.BTL. Unpublished data submitted by Personal Care Products Council; 2004:15.
Google Scholar44. Active Concepts . Bacterial Reverse Mutation Test (AC Cashmere Hydrolysate- Solution Hydrolyzed Keratin from Goat Wool). Unpublished data submitted by Personal Care Products Council; 2016.
Google Scholar45. Active Concepts . Bacterial Reverse Mutation Test (AC Keratin Hydrolysate 30 - Solution Hydrolyzed Keratin from Sheep Wool). Unpublished data submitted by Personal Care Products Council; 2016.
Google Scholar46. Active Concepts . Bacterial Reverse Mutation Test (AC Keratin Hydrolysate SD- Powder Hydrolyzed Keratin from Sheep Wool). Unpublished data submitted by Personal Care Products Council; 2016.
Google Scholar47. Anonymous . Summary of Keratin Safety Studies. Unpublished data submitted by Personal Care Products Council; 2016.
Google Scholar48. Toxicol Laboratories Limited . Primary Skin Irritation Study: Hydrolyzed Keratin (MW - 125,000 Da) Study Ref. No. 63/8601. Unpublished data submitted by Personal Care Products Council; 1986.
Google Scholar49. Active Concepts . AC Cashmere Hydrolysate Irritation Analysis (AC Cashmere Hydrolysate - solution Hydrolyzed Keratin from Goat Wool). Unpublished data submitted by Personal Care Products Council; 2007.
Google Scholar50. Active Concepts . Dermal and Ocular Irritation Tests (AC Keratin Hydrolysate 30 - Solution Hydrolyzed Keratin from Sheep Wool). Unpublished data submitted by Personal Care Products Council; 2015.
Google Scholar51. Active Concepts . Dermal and Ocular Irritation Tests (AC Keratin Hydrolysate SD - Powder Hydrolyzed Keratin from Sheep Wool). Unpublished data submitted by Personal Care Products Council; 2012.
Google Scholar52. Consumer Product Testing Co . Primary dermal irritation in rabbits; primary ocular irritation in rabbits, acute oral toxicity in rats: Hydrolyzed Keratin (MW ∼ 600 Da). Experiment Reference No: 81103-S. Unpublished data submitted by Personal Care Products Council; 1981.
Google Scholar53. Consumer Product Testing Co . Primary dermal irritation in rabbits; primary ocular irritation in rabbits; acute oral toxicity in rabbits: Hydrolyzed Keratin (MW ∼ 500 Da) Experiment Reference No. 84229 -1. Unpublished data submitted by Personal Care Products Council; 1984.
Google Scholar54. Consumer Product Testing Co . The MatTek Corporation EpiDerm™ skin model in vitro toxicity testing system: Hydrolyzed Keratin (MW ∼ 3,000 Da). Experiment Reference Number: V04-0032 -1. Unpublished data submitted by Personal Care Products Council; 2004.
Google Scholar55. Toxicol Laboratories Limited . Primary Skin Irritation Study (20% Hydrolyzed Keratin from Hoof Meal). Unpublished data submitted by the Personal Care Products Council; 1986.
Google Scholar56. Food and Drug Research Laboratories, Inc . Rabbit Eye Irritation Study (20% Hydrolyzed Keratin from Hoof Meal). Unpublished data submitted by the Personal Care Products Council; 1976.
Google Scholar57. Anonymous . Summary: Study of Primary Cutaneous Irritation of a Pharmaceutical or Cosmetic Compound in the Male Rabbit. Unpublished data submitted by Personal Care Products Council; 2001.
Google Scholar58. Food and Drug Research Laboratories, Inc . Primary Skin Irritation study with Rabbits (20% Hydrolyzed Keratin from Hoof Meal). Unpublished data submitted by the Personal Care Products Council; 1976.
Google Scholar59. Consumer Product Testing Co . The Hen’s egg test -- utilizing the chorioallantoic membrane (HET-CAM): Hydrolyzed Keratin (MW - 3,000 Da) Experiment Reference Number: V04-0033 -1. Unpublished data submitted by Personal Care Products Council; 2004.
Google Scholar60. Toxicol Laboratories Limited . Eye irritation study: Hydrolyzed Keratin (MW - 125,000 Da) Study Ref. No. 64/8601. Unpublished data submitted by Personal Care Products Council; 1986.
Google Scholar61. Toxicol Laboratories Limited . Eye irritation study (20% Hydrolyzed Keratin from hoof meal). Unpublished data submitted by the Personal Care Products Council; 1986.
Google Scholar62. Anonymous . Study of ocular irritation of a pharmaceutical or cosmetic compound in the male rabbit. Unpublished data submitted by Personal Care Products Council; 2001.
Google Scholar63. Active Concepts . OECD TO 4420: In vitro skin sensitization (AC Cashmere Hydrolysate - solution Hydrolyzed Keratin from goat wool). Unpublished data submitted by Personal Care Products Council; 2015.
Google Scholar64. Active Concepts . OECD TO 442D: In vitro skin sensitization (AC Keratin Hydrolysate SD - powder Hydrolyzed Keratin from sheep wool). Unpublished data submitted by Personal Care Products Council; 2015.
Google Scholar65. Active Concepts . OECO TG 4420: In vitro skin sensitization (AC Keratin Hydrolysate 30 - solution Hydrolyzed Keratin from sheep wool). Unpublished data submitted by Personal Care Products Council; 2015.
Google Scholar66. Consumer Product Testing Co . Repeated insult patch test: Hydrolyzed Keratin (MW ∼ 3,000 Da). Experiment Reference Number: C04-0181.01. Unpublished data submitted by Personal Care Products Council; 2004.
Google Scholar67. McFadden, JP, Rycroft, RJG, White, IR, Wakelin, SH, Basketter, DA. Hydrolyzed protein shampoo additives are not a common contact allergen. Contact Dermatitis. 2000;43(4):243–243.
Google Scholar | Medline68. Niinimaki, A, Niinimaki, M, Makinen-Kiljunen, S, Hannuksela, M. Contact urticaria from protein hydrolysates in hair conditioners. Allergy. 1998;53(11):1078–1082.
Google Scholar | Crossref | Medline69. Freeman, S, Lee, MS. Contact urticaria to hair conditioner. Contact Dermatitis. 1996;35(3):195–196.
Google Scholar | Crossref | Medline70. Active Concepts . Product specification (AC Keratin Hydrolysate SD- powder Hydrolyzed Keratin from sheep wool). Unpublished data submitted by Personal Care Products Council; 2014.
Google Scholar71. Active Concepts . Product specification (AC Keratin Hydrolysate 30- solution Hydrolyzed Keratin from sheep wool). Unpublished data submitted by Personal Care Products Council; 2015.
Google Scholar72. Active Concepts .

留言 (0)

沒有登入
gif