Identification of a Preliminary Plasma Metabolome-based Biomarker for Circadian Phase in Humans

Alfred, LJ, Wehr, TA, Goodwin, FK, Newsome, DA, Markey, SP (1980) Light suppresses melatonin secretion in humans. Science 210:1267-1269.
Google Scholar | Crossref | Medline Ang, JE, Revell, V, Mann, A, Mantele, S, Otway, DT, Johnston, JD, Thumser, AE, Skene, DJ, Raynaud, F (2012) Identification of human plasma metabolites exhibiting time-of-day variation using an untargeted liquid chromatography-mass spectrometry metabolomic approach. Chronobiol Int 29:868-881.
Google Scholar | Crossref | Medline Baron, KG, Reid, KJ (2014) Circadian misalignment and health. Int Rev Psychiatry 26:139-154.
Google Scholar | Crossref | Medline | ISI Benloucif, S, Burgess, HJ, Klerman, EB, Lewy, AJ, Middleton, B, Murphy, PJ, Parry, BL, Revell, VL (2008) Measuring melatonin in humans. J Clin Sleep Med 4:66-69.
Google Scholar | Crossref | Medline | ISI Boulesteix, AL, Strimmer, K (2007) Partial least squares: A versatile tool for the analysis of high-dimensional genomic data. Brief Bioinform 8:32-44.
Google Scholar | Crossref | Medline | ISI Braun, R, Kath, WL, Iwanaszko, M, Kula-Eversole, E, Abbott, SM, Reid, KJ, Zee, PC, Allada, R (2018) Universal method for robust detection of circadian state from gene expression. Proc Natl Acad Sci U S A 115:E9247-E9256.
Google Scholar | Crossref | Medline Braun, R, Kath, WL, Iwanaszko, M, Kula-Eversole, E, Abbott, SM, Reid, KJ, Zee, PC, Allada, R (2019) Reply to Laing et al.: accurate prediction of circadian time across platforms. Proc Natl Acad Sci U S A 116:5206-5208.
Google Scholar | Crossref Broussard, JL, Reynolds, AC, Depner, CM, Ferguson, SA, Dawson, D, Wright, KP (2017) Circadian rhythms versus daily patterns in human physiology and behavior. In: Kumar, V , editor. Biological timekeeping: clocks, rhythms and behavior. New Delhi (India): Springer. p. 279-295.
Google Scholar | Crossref Buijs, RM, Wortel, J, Van Heerikhuize, JJ, Feenstra, MG, Ter Horst, GJ, Romijn, HJ, Kalsbeek, A (1999) Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway. Eur J Neurosci 11:1535-1544.
Google Scholar | Crossref | Medline | ISI Cheng, P, Walch, O, Huang, Y, Mayer, C, Sagong, C, Cuamatzi Castelan, A, Burgess, HJ, Roth, T, Forger, DB, Drake, CL (2021) Predicting circadian misalignment with wearable technology: validation of wrist-worn actigraphy and photometry in night shift workers. Sleep 44:zsaa180.
Google Scholar | Crossref Chong, J, Soufan, O, Li, C, Caraus, I, Li, S, Bourque, G, Wishart, DS, Xia, J (2018) MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis. Nucleic Acids Res 46:W486-W494.
Google Scholar | Crossref | Medline Chua, EC, Shui, G, Cazenave-Gassiot, A, Wenk, MR, Gooley, JJ (2015) Changes in plasma lipids during exposure to total sleep deprivation. Sleep 38:1683-1691.
Google Scholar | Crossref | Medline Chua, EC, Shui, G, Lee, IT, Lau, P, Tan, LC, Yeo, SC, Lam, BD, Bulchand, S, Summers, SA, Puvanendran, K, et al. (2013) Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans. Proc Natl Acad Sci U S A 110:14468-14473.
Google Scholar | Crossref | Medline | ISI Cruickshank-Quinn, C, Quinn, KD, Powell, R, Yang, Y, Armstrong, M, Mahaffey, S, Reisdorph, R, Reisdorph, N (2014) Multi-step preparation technique to recover multiple metabolite compound classes for in-depth and informative metabolomic analysis. J Vis Exp 89:51670.
Google Scholar Dallmann, R, Viola, AU, Tarokh, L, Cajochen, C, Brown, SA (2012) The human circadian metabolome. Proc Natl Acad Sci U S A 109:2625-2629.
Google Scholar | Crossref | Medline | ISI Depner, C, Cheng, PC, Devine, JK, Khosla, S, de Zambotti, M, Robillard, R, Vakulin, A, Drummond, SPA (2020) Wearable technologies for developing sleep and circadian biomarkers: a summary of workshop discussions. Sleep 43:zsz254.
Google Scholar Depner, C, Cogswell, DT, Bisesi, PJ, Markwald, RR, Cruickshank-Quinn, C, Quinn, KD, Melanson, EL, Reisdorph, N, Wright, KP (2020) Developing preliminary blood metabolomics-based biomarkers of insufficient sleep in humans. Sleep 43:zsz321.
Google Scholar | Crossref Depner, C, Melanson, EL, McHill, AW, Wright, KP (2018) Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome. Proc Natl Acad Sci U S A 115:E5390-E5399.
Google Scholar | Crossref | Medline Dijk, DJ, Duffy, JF (2020) Novel approaches for assessing circadian rhythmicity in humans: a review. J Biol Rhythms 35:421-438.
Google Scholar | SAGE Journals | ISI Drake, CL, Wright, KP (2017) Shift work, shift-work disorder, and jet lag. In: Kryger, MH, Roth, T, Dement, WC, editors. Principles and practice of sleep medicine, 6th Edition. p. 784-798.
Google Scholar | Crossref Duffy, JF, Abbott, SM, Burgess, HJ, Crowley, SJ, Emens, JS, Epstein, LJ, Gamble, KL, Hasler, BP, Kristo, DA, Malkani, RG, et al. (2021) Workshop report. Circadian rhythm sleep-wake disorders: gaps and opportunities. Sleep 44:zsaa281.
Google Scholar | Crossref Duffy, JF, Dijk, DJ (2002) Getting through to circadian oscillators: why use constant routines? J Biol Rhythms 17:4-13.
Google Scholar | SAGE Journals | ISI Duffy, JF, Cain, SW, Chang, AM, Phillips, AJ, Münch, MY, Gronfier, C, Wyatt, JK, Dijk, DJ, Wright, KP, Czeisler, CA (2011) Sex difference in the near-24-hour intrinsic period of the human circadian timing system. Proc Natl Acad Sci U S A 108:15602-15608.
Google Scholar | Crossref | Medline | ISI Eckel, RH, Depner, CM, Perreault, L, Markwald, RR, Smith, MR, McHill, AW, Higgins, J, Melanson, EL, Wright, KP (2015) Morning circadian misalignment during short sleep duration impacts insulin sensitivity. Curr Biol 25:3004-3010.
Google Scholar | Crossref | Medline | ISI Eggink, HM, Oosterman, JE, de Goede, P, de Vries, EM, Foppen, E, Koehorst, M, Groen, AK, Boelen, A, Romijn, JA, la Fleur, SE, et al. (2017) Complex interaction between circadian rhythm and diet on bile acid homeostasis in male rats. Chronobiol Int 34:1339-1353.
Google Scholar | Crossref | Medline Funai, K, Lodhi, IJ, Spears, LD, Yin, L, Song, H, Klein, S, Semenkovich, CF (2016) Skeletal muscle phospholipid metabolism regulates insulin sensitivity and contractile function. Diabetes 65:358-370.
Google Scholar | Crossref | Medline Gil, EA, Aubert, XL, Most, EI, Beersma, DG (2013) Human circadian phase estimation from signals collected in ambulatory conditions using an autoregressive model. J Biol Rhythms 28:152-163.
Google Scholar | SAGE Journals | ISI Gooley, JJ, Chua, EC (2014) Diurnal regulation of lipid metabolism and applications of circadian lipidomics. J Genet Genomics 41:231-250.
Google Scholar | Crossref | Medline Hermida, RC, Crespo, JJ, Domínguez-Sardiña, M, Otero, A, Moyá, A, Ríos, MT, Sineiro, E, Castiñeira, MC, Callejas, PA, Pousa, L, et al. (2020) Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial. Eur Heart J 41:4565-4576.
Google Scholar | Crossref | Medline Hoyle, NP, Seinkmane, E, Putker, M, Feeney, KA, Krogager, TP, Chesham, JE, Bray, LK, Thomas, JM, Dunn, K, Blaikley, J, et al. (2017) Circadian actin dynamics drive rhythmic fibroblast mobilization during wound healing. Sci Transl Med 9:eaal2774.
Google Scholar | Crossref | Medline Hrushesky, WJM (1985) Circadian timing of cancer chemotherapy. Science 228:73-75.
Google Scholar | Crossref | Medline | ISI Hughes, G, Cruickshank-Quinn, C, Reisdorph, R, Lutz, S, Petrache, I, Reisdorph, N, Bowler, R, Kechris, K (2014) MSPrep—summarization, normalization and diagnostics for processing of mass spectrometry-based metabolomic data. Bioinformatics 30:133-134.
Google Scholar | Crossref | Medline Hughey, JJ (2017) Machine learning identifies a compact gene set for monitoring the circadian clock in human blood. Genome Med 9:19.
Google Scholar | Crossref | Medline | ISI Innominato, PF, Giacchetti, S, Bjarnason, GA, Focan, C, Garufi, C, Coudert, B, Iacobelli, S, Tampellini, M, Durando, X, Mormont, MC, et al. (2012) Prediction of overall survival through circadian rest-activity monitoring during chemotherapy for metastatic colorectal cancer. Int J Cancer 131:2684-2692.
Google Scholar | Crossref | Medline Isherwood, CM, Van der Veen, DR, Johnston, JD, Skene, DJ (2017) Twenty-four-hour rhythmicity of circulating metabolites: effect of body mass and type 2 diabetes. Faseb J 31:5557-5567.
Google Scholar | Crossref | Medline Jewison, T, Su, Y, Disfany, FM, Liang, Y, Knox, C, Maciejewski, A, Poelzer, J, Huynh, J, Zhou, Y, Arndt, D, et al. (2014) SMPDB 2.0: big improvements to the small molecule pathway database. Nucleic Acids Res 42:D478-D484.
Google Scholar | Crossref | Medline Johnson, WE, Li, C, Rabinovic, A (2007) Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics 8:118-127.
Google Scholar | Crossref | Medline | ISI Kanehisa, M, Goto, S (2000) KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28:27-30.
Google Scholar | Crossref | Medline | ISI Kasukawa, T, Sugimoto, M, Hida, A, Minami, Y, Mori, M, Honma, S, Honma, K, Mishima, K, Soga, T, Ueda, HR (2012) Human blood metabolite timetable indicates internal body time. Proc Natl Acad Sci U S A 109:15036-15041.
Google Scholar | Crossref | Medline | ISI Keppel, G (1991) Design and analysis: a researcher’s handbook. Englewood Cliffs (NJ): Prentice Hall.
Google Scholar Kervezee, L, Cermakian, N, Boivin, DB (2019) Individual metabolomic signatures of circadian misalignment during simulated night shifts in humans. PLoS Biol 17:e3000303.
Google Scholar | Crossref | Medline Kervezee, L, Cuesta, M, Cermakian, N, Boivin, DB (2019) The phase-shifting effect of bright light exposure on circadian rhythmicity in the human transcriptome. J Biol Rhythms 34:84-97.
Google Scholar | SAGE Journals | ISI Klerman, EB, Gershengorn, HB, Duffy, JF, Kronauer, RE (2002) Comparisons of the variability of three markers of the human circadian pacemaker. J Biol Rhythms 17:181-193.
Google Scholar | SAGE Journals | ISI Kuhn, M (2008) Building predictive models in R using the caret package. J Stat Softw 28(5):1-26.
Google Scholar Labrecque, G, Belanger, PM (1992) Biological rhythms in the absorption distribution, metabolism, and excretion of drugs. Pharmacol Ther 52:95-107.
Google Scholar | Crossref Lagace, TA, Ridgway, ND (2013) The role of phospholipids in the biological activity and structure of the endoplasmic reticulum. Biochim Biophys Acta 1833:2499-2510.
Google Scholar | Crossref | Medline | ISI Laing, EE, Moller-Levet, CS, Archer, SN, Dijk, DJ (2019) Universal and robust assessment of circadian time? Proc Natl Acad Sci U S A 116:5205.
Google Scholar | Crossref | Medline Laing, EE, Moller-Levet, CS, Poh, N, Santhi, N, Archer, SN, Dijk, DJ (2017) Blood transcriptome based biomarkers for human circadian phase. eLife 6:e20214.
Google Scholar | Crossref | Medline | ISI Lemmer, B, Scheidel, B, Behne, S (1992) Chronopharmacokinetics and chronopharmacodynamics of cardiovascular active drugs: propranolol, organic nitrates, nifedipine. Ann N Y Acad Sci 618:166-181.

留言 (0)

沒有登入
gif